Symbol Name ID |
Piezo1
piezo-type mechanosensitive ion channel component 1 MGI:3603204 |
Age | E9 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 2 | 1 | 1 | 2 | ||||||||
In situ RNA (section) | 1 | 1 | 1 | 2 | 1 | ||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | |||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | 1 | ||||||||||
Western blot | 2 | ||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 4 |
Piezo1 piezo-type mechanosensitive ion channel component 1 (Synonyms: Fam38a, Piezo1) | |
Results | Reference |
6* | J:197533 Andolfo I, Alper SL, De Franceschi L, Auriemma C, Russo R, De Falco L, Vallefuoco F, Esposito MR, Vandorpe DH, Shmukler BE, Narayan R, Montanaro D, D'Armiento M, Vetro A, Limongelli I, Zuffardi O, Glader BE, Schrier SL, Brugnara C, Stewart GW, Delaunay J, Iolascon A, Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1. Blood. 2013 May 9;121(19):3925-35, S1-12 |
1 | J:348695 David L, Martinez L, Xi Q, Kooshesh KA, Zhang Y, Shah JV, Maas RL, Wu H, Piezo mechanosensory channels regulate centrosome integrity and mitotic entry. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213846120 |
4* | J:347773 Kim HY, Kang B, Lee PR, Kim K, Hong GS, Expression patterns of Piezo1 in the developing mouse forebrain. Brain Struct Funct. 2024 Apr;229(3):759-773 |
2 | J:217082 Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow MJ, Sedo A, Hyman AJ, McKeown L, Young RS, Yuldasheva NY, Majeed Y, Wilson LA, Rode B, Bailey MA, Kim HR, Fu Z, Carter DA, Bilton J, Imrie H, Ajuh P, Dear TN, Cubbon RM, Kearney MT, Prasad KR, Evans PC, Ainscough JF, Beech DJ, Piezo1 integration of vascular architecture with physiological force. Nature. 2014 Nov 13;515(7526):279-82 |
1 | J:347984 Naillat F, Deshar G, Hankkila A, Rak-Raszewska A, Sharma A, Prunskaite-Hyyrylainen R, Railo A, Shan J, Vainio SJ, Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167180 |
5 | J:348078 Nie X, Abbasi Y, Chung MK, Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386 |
1* | J:333869 Nourse JL, Leung VM, Abuwarda H, Evans EL, Izquierdo-Ortiz E, Ly AT, Truong N, Smith S, Bhavsar H, Bertaccini G, Monuki ES, Panicker MM, Pathak MM, Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development. J Gen Physiol. 2022 Oct 3;154(10) |
4 | J:334608 Pokharel E, Aryal YP, Kim TY, Kim A, Kim JY, Yamamoto H, Cho SW, Sohn WJ, Kim JY, Jung JK, Developmental function of Piezo1 in mouse submandibular gland morphogenesis. Histochem Cell Biol. 2023 Feb 22; |
6* | J:212179 Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A, Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52 |
6 | J:292430 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y, Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Elife. 2020 Mar 18;9:e52779 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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