Symbol Name ID |
Shank1
SH3 and multiple ankyrin repeat domains 1 MGI:3613677 |
Age | E10.5 | E12 | E13 | E14 | E15 | E17.5 | E18.5 | P |
Immunohistochemistry (section) | 4 | |||||||
In situ RNA (section) | 1 | 2 | ||||||
Western blot | 1 | 2 | ||||||
RT-PCR | 1 | 1 | 1 | 2 | 3 | |||
cDNA clones | 1 | 1 | 1 |
Shank1 SH3 and multiple ankyrin repeat domains 1 | |
Results | Reference |
4* | J:266512 Berkel S, Eltokhi A, Frohlich H, Porras-Gonzalez D, Rafiullah R, Sprengel R, Rappold GA, Sex Hormones Regulate SHANK Expression. Front Mol Neurosci. 2018;11:337 |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
1 | J:306456 Farini D, Cesari E, Weatheritt RJ, La Sala G, Naro C, Pagliarini V, Bonvissuto D, Medici V, Guerra M, Di Pietro C, Rizzo FR, Musella A, Carola V, Centonze D, Blencowe BJ, Marazziti D, Sette C, A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum. Cell Rep. 2020 Jun 2;31(9):107703 |
1 | J:191194 Huang LC, Barclay M, Lee K, Peter S, Housley GD, Thorne PR, Montgomery JM, Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea. Neural Dev. 2012;7:38 |
1 | J:227951 Mendus D, Sundaresan S, Grillet N, Wangsawihardja F, Leu R, Muller U, Jones SM, Mustapha M, Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear. Eur J Neurosci. 2014 Apr;39(8):1256-67 |
1* | J:249252 Quesnel-Vallieres M, Dargaei Z, Irimia M, Gonatopoulos-Pournatzis T, Ip JY, Wu M, Sterne-Weiler T, Nakagawa S, Woodin MA, Blencowe BJ, Cordes SP, Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders. Mol Cell. 2016 Dec 15;64(6):1023-1034 |
1 | J:221584 Quesnel-Vallieres M, Irimia M, Cordes SP, Blencowe BJ, Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59 |
1 | J:148808 Sawallisch C, Berhorster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ, The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem. 2009 Apr 3;284(14):9225-36 |
5 | J:107647 Thuret S, Bhatt L, O'Leary DD, Simon HH, Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta. Mol Cell Neurosci. 2004 Mar;25(3):394-405 |
3* | J:108736 Uchino S, Wada H, Honda S, Nakamura Y, Ondo Y, Uchiyama T, Tsutsumi M, Suzuki E, Hirasawa T, Kohsaka S, Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor. J Neurochem. 2006 May;97(4):1203-14 |
1 | J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020 |
1 | J:255264 Zhang J, Weinrich JAP, Russ JB, Comer JD, Bommareddy PK, DiCasoli RJ, Wright CVE, Li Y, van Roessel PJ, Kaltschmidt JA, A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry. Cell Rep. 2017 Oct 17;21(3):666-678 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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