Gene Expression Literature Summary

• Symbol: Mir503
• Name: microRNA 503
• ID: MGI:3619428

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16.5	E18.5	P
In situ RNA (section)						2
In situ reporter (knock in)		1
Northern blot	1	1	1							1	1
RT-PCR	2	1	1	3	2	1	1	1	1	2	3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mir503  microRNA 503   (Synonyms: mir 503, Mirn503, mmu-mir-503)
Results	Reference
1	J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
6*	J:336590 Huang R, Liu J, Chen X, Zhi Y, Ding S, Ming J, Li Y, Wang Y, Na J, A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions. Protein Cell. 2023 Mar 16;14(2):153-157
1*	J:338912 Jones BT, Han J, Zhang H, Hammer RE, Evers BM, Rakheja D, Acharya A, Mendell JT, Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Genes Dev. 2023 Aug 8;
1	J:350800 Liang R, Shen X, Wang F, Wang X, DesJarlais A, Syed A, Saba R, Tan Z, Yu F, Ji X, Shrestha S, Ren Y, Yang J, Park Y, Schwartz RJ, Soibam B, McConnell BK, Stewart MD, Kumar A, Liu Y, H19X-encoded miR-322(424)/miR-503 regulates muscle mass by targeting translation initiation factors. J Cachexia Sarcopenia Muscle. 2021 Dec;12(6):2174-2186
3*	J:151446 Liu B, Cunha GR, Baskin LS, Differential expression of microRNAs in mouse embryonic bladder. Biochem Biophys Res Commun. 2009 Aug 7;385(4):528-33
1*	J:132315 Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS, MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 2007 Dec;56(12):2938-45
3*	J:108513 Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K, Mirochnitchenko O, Inouye M, Kato I, The expression profile of microRNAs in mouse embryos. Nucleic Acids Res. 2006;34(6):1765-71
4	J:315740 Prevot PP, Augereau C, Simion A, Van den Steen G, Dauguet N, Lemaigre FP, Jacquemin P, Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6. Gastroenterology. 2013 Sep;145(3):668-78.e3
1*	J:235603 Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, Liu Y, miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9551-6
1	J:308530 Shen X, Xu F, Li M, Wu S, Zhang J, Wang A, Xu L, Liu Y, Zhu G, miR-322/-503 rescues myoblast defects in myotonic dystrophy type 1 cell model by targeting CUG repeats. Cell Death Dis. 2020 Oct 22;11(10):891
3	J:344870 Zhou Y, Liu K, Tang W, Zhang Y, Sun Y, Wu Y, Shi Y, Yao Z, Li Y, Bai R, Liang R, Sun P, Chang X, Wang S, Zhu Y, Han X, beta-Cell miRNA-503-5p Induced by Hypomethylation and Inflammation Promotes Insulin Resistance and beta-Cell Decompensation. Diabetes. 2024 Jan 1;73(1):57-74