Symbol Name ID |
Mir92-2
microRNA 92-2 MGI:3619438 |
Age | E0.5 | E1 | E2 | E2.5 | E6.5 | E7.5 | E8.5 | E10 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15.5 | E16.5 | E18 | E18.5 | P |
In situ RNA (section) | 1 | 2 | 2 | 1 | ||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | |||||||||||||||||
Northern blot | 1 | 1 | 2 | |||||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 5 |
Mir92-2 microRNA 92-2 (Synonyms: mir 92-2, Mirn92-2, mmu-mir-92-2, mmu-mir-92a-2) | |
Results | Reference |
4 | J:269810 Bian S, Hong J, Li Q, Schebelle L, Pollock A, Knauss JL, Garg V, Sun T, MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex. Cell Rep. 2013 May 30;3(5):1398-1406 |
2 | J:263996 Cao H, Yu W, Li X, Wang J, Gao S, Holton NE, Eliason S, Sharp T, Amendt BA, A new plasmid-based microRNA inhibitor system that inhibits microRNA families in transgenic mice and cells: a potential new therapeutic reagent. Gene Ther. 2016 Jun;23(6):527-42 |
1* | J:279273 Chen G, Yao Y, Xu G, Zhang X, Regional difference in microRNA regulation in the skull vault. Dev Dyn. 2019 Oct;248(10):1009-1019 |
1 | J:213298 Chen J, Huang ZP, Seok HY, Ding J, Kataoka M, Zhang Z, Hu X, Wang G, Lin Z, Wang S, Pu WT, Liao R, Wang DZ, mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ Res. 2013 Jun 7;112(12):1557-66 |
1 | J:186203 Chen Z, Wu J, Yang C, Fan P, Balazs L, Jiao Y, Lu M, Gu W, Li C, Pfeffer LM, Tigyi G, Yue J, DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice. J Biol Chem. 2012 Jun 1;287(23):19018-28 |
1 | J:188762 de Pontual L, Yao E, Callier P, Faivre L, Drouin V, Cariou S, Van Haeringen A, Genevieve D, Goldenberg A, Oufadem M, Manouvrier S, Munnich A, Vidigal JA, Vekemans M, Lyonnet S, Henrion-Caude A, Ventura A, Amiel J, Germline deletion of the miR-17 approximately 92 cluster causes skeletal and growth defects in humans. Nat Genet. 2011 Oct;43(10):1026-30 |
2 | J:111626 Deo M, Yu JY, Chung KH, Tippens M, Turner DL, Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn. 2006 May 30;235(9):2538-2548 |
1 | J:208305 Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ, Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure. Nat Cell Biol. 2013 Nov;15(11):1282-93 |
4* | J:186286 Li L, Shi JY, Zhu GQ, Shi B, MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFB pathway in mouse palatal mesenchymal cells. J Cell Biochem. 2012 Apr;113(4):1235-44 |
1 | J:172088 Pan Y, Balazs L, Tigyi G, Yue J, Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality. Biochem Biophys Res Commun. 2011 May 13;408(3):369-74 |
3 | J:213695 Pernaute B, Spruce T, Smith KM, Sanchez-Nieto JM, Manzanares M, Cobb B, Rodriguez TA, MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM. Genes Dev. 2014 Sep 1;28(17):1873-8 |
3 | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
2 | J:163670 Spruce T, Pernaute B, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M, Rodriguez TA, An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo. Dev Cell. 2010 Aug 17;19(2):207-19 |
5 | J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8 |
1 | J:287165 Wang J, Lee JE, Riemondy K, Yu Y, Marquez SM, Lai EC, Yi R, XPO5 promotes primary miRNA processing independently of RanGTP. Nat Commun. 2020 Apr 15;11(1):1845 |
4* | J:124661 Xu S, Witmer PD, Lumayag S, Kovacs B, Valle D, MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster. J Biol Chem. 2007 Aug 24;282(34):25053-66 |
1 | J:170443 Yi R, Poy MN, Stoffel M, Fuchs E, A skin microRNA promotes differentiation by repressing 'stemness'. Nature. 2008 Mar 13;452(7184):225-9 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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