Gene Expression Literature Summary

• Symbol: Apela
• Name: apelin receptor early endogenous ligand
• ID: MGI:3642370

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E17.5	P
Immunohistochemistry (section)									1
In situ RNA (section)		1	2	3	1	1		1	1	1						2
Immunohistochemistry (whole mount)	1	1	1	1			1							1
In situ RNA (whole mount)			1	2	2	2	1	1	1
In situ reporter (knock in)			1
RT-PCR	1		2		1		2		1	3	1	1	2	1	1	1
cDNA clones					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Apela  apelin receptor early endogenous ligand   (Synonyms: Ela, Elabela, Ende, Gm10664)
Results	Reference
1	J:332240 Feng W, Bais A, He H, Rios C, Jiang S, Xu J, Chang C, Kostka D, Li G, Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages. Nat Commun. 2022 Dec 27;13(1):7960
13	J:243623 Freyer L, Hsu CW, Nowotschin S, Pauli A, Ishida J, Kuba K, Fukamizu A, Schier AF, Hoodless PA, Dickinson ME, Hadjantonakis AK, Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell Rep. 2017 Aug 29;20(9):2116-2130
22*	J:158268 Hassan AS, Hou J, Wei W, Hoodless PA, Expression of two novel transcripts in the mouse definitive endoderm. Gene Expr Patterns. 2010 Feb 12;10(2-3):127-34
5	J:244834 Ho L, van Dijk M, Chye STJ, Messerschmidt DM, Chng SC, Ong S, Yi LK, Boussata S, Goh GH, Afink GB, Lim CY, Dunn NR, Solter D, Knowles BB, Reversade B, ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice. Science. 2017 Aug 18;357(6352):707-713
4	J:316080 Jackson M, Fidanza A, Taylor AH, Rybtsov S, Axton R, Kydonaki M, Meek S, Burdon T, Medvinsky A, Forrester LM, Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System. Stem Cell Reports. 2021 Apr 13;16(4):727-740
1	J:283357 Nowotschin S, Setty M, Kuo YY, Liu V, Garg V, Sharma R, Simon CS, Saiz N, Gardner R, Boutet SC, Church DM, Hoodless PA, Hadjantonakis AK, Pe'er D, The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature. 2019 May;569(7756):361-367
1	J:286013 Outhwaite JE, Patel J, Simmons DG, Secondary Placental Defects in Cxadr Mutant Mice. Front Physiol. 2019;10:622
1	J:245878 Sharma B, Ho L, Ford GH, Chen HI, Goldstone AB, Woo YJ, Quertermous T, Reversade B, Red-Horse K, Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. Dev Cell. 2017 Sep 25;42(6):655-666.e3
1*	J:143778 Tamplin OJ, Cox BJ, Rossant J, Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Dev Biol. 2011 Dec 15;360(2):415-25