Gene Expression Literature Summary

• Symbol: Abl1
• Name: c-abl oncogene 1, non-receptor tyrosine kinase
• ID: MGI:87859

27 matching records from 27 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E8.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)			1		2																	2
In situ RNA (section)			1		1		1				1	1	2		1	1			1	1		3
Immunohistochemistry (whole mount)	1																					1
Northern blot																						1
Western blot			1	2		1		1		1		1		3		2	1		1	1	1	4
RT-PCR		2			1	1		1	1		1		1					1			1	4
cDNA clones		2									1				1			1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Abl1  c-abl oncogene 1, non-receptor tyrosine kinase   (Synonyms: c-Abl, E430008G22Rik)
Results	Reference
1	J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331
1	J:125289 Backer S, Hidalgo-Sanchez M, Offner N, Portales-Casamar E, Debant A, Fort P, Gauthier-Rouviere C, Bloch-Gallego E, Trio controls the mature organization of neuronal clusters in the hindbrain. J Neurosci. 2007 Sep 26;27(39):10323-32
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
4*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1	J:198786 Chislock EM, Ring C, Pendergast AM, Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12432-7
9*	J:72871 Courtney KD, Grove M, Vandongen H, Vandongen A, LaMantia AS, Pendergast AM, Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system. Mol Cell Neurosci. 2000 Sep;16(3):244-57
4	J:287553 Kim JY, Cho B, Moon C, Timely Inhibitory Circuit Formation Controlled by Abl1 Regulates Innate Olfactory Behaviors in Mouse. Cell Rep. 2020 Jan 7;30(1):187-201.e4
4*	J:51887 Koleske AJ, Gifford AM, Scott ML, Nee M, Bronson RT, Miczek KA, Baltimore D, Essential roles for the Abl and Arg tyrosine kinases in neurulation. Neuron. 1998 Dec;21(6):1259-72
1	J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
6	J:57954 Lay JM, Gillespie PJ, Samuelson LC, Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells. Dev Dyn. 1999 Oct;216(2):190-200
1	J:308052 Liang F, Wang B, Geng J, You G, Fa J, Zhang M, Sun H, Chen H, Fu Q, Zhang X, Zhang Z, SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients. Elife. 2021 Jun 8;10:e67481
2	J:315975 Mutluay D, Oner H, The Abelson tyrosine kinase (c-Abl) localization in preimplantation mouse development. Rom J Morphol Embryol. 2017;58(4):1385-1391
3	J:156743 Qiu Z, Cang Y, Goff SP, c-Abl tyrosine kinase regulates cardiac growth and development. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1136-41
1	J:166211 Qiu Z, Cang Y, Goff SP, Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum. J Neurosci. 2010 Oct 27;30(43):14430-9
1	J:28731 Reith AD, Isolation and chromosomal location of Nsk1, a novel murine putative receptor tyrosine kinase. Mamm Genome. 1995 Sep;6(9):689
1	J:22208 Ruiz JC, Conlon FL, Robertson EJ, Identification of novel protein kinases expressed in the myocardium of the developing mouse heart. Mech Dev. 1994 Dec;48(3):153-64
1*	J:178219 Shackleford GM, Varmus HE, Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos. Cell. 1987 Jul 3;50(1):89-95
1	J:27414 Sommers CL, Huang K, Shores EW, Grinberg A, Charlick DA, Kozak CA, Love PE, Murine txk: a protein tyrosine kinase gene regulated by T cell activation. Oncogene. 1995 Jul 20;11(2):245-51
2*	J:261957 Svandova EB, Vesela B, Lesot H, Poliard A, Matalova E, Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination. Histochem Cell Biol. 2017 Apr;147(4):497-510
1	J:102097 Tay J, Richter JD, Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev Cell. 2001 Aug;1(2):201-13
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
3	J:91730 Verma-Kurvari S, Parada LF, Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Dev Dyn. 2004 Aug;230(4):660-5
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:348704 Vong KI, Lee S, Au KS, Crowley TB, Capra V, Martino J, Haller M, Araujo C, Machado HR, George R, Gerding B, James KN, Stanley V, Jiang N, Alu K, Meave N, Nidhiry AS, Jiwani F, Tang I, Nisal A, Jhamb I, Patel A, Patel A, McEvoy-Venneri J, Barrows C, Shen C, Ha YJ, Howarth R, Strain M, Ashley-Koch AE, Azam M, Mumtaz S, Bot GM, Finnell RH, Kibar Z, Marwan AI, Melikishvili G, Meltzer HS, Mutchinick OM, Stevenson DA, Mroczkowski HJ, Ostrander B, Schindewolf E, Moldenhauer J, Zackai EH, Emanuel BS, Garcia-Minaur S, Nowakowska BA, Stevenson RE, Zaki MS, Northrup H, McNamara HK, Aldinger KA, Phelps IG, Deng M, Glass IA, Morrow B, McDonald-McGinn DM, Sanna-Cherchi S, Lamb DJ, Gleeson JG, Risk of meningomyelocele mediated by the common 22q11.2 deletion. Science. 2024 May 3;384(6695):584-590
1	J:205485 Yu C, Zhang YL, Pan WW, Li XM, Wang ZW, Ge ZJ, Zhou JJ, Cang Y, Tong C, Sun QY, Fan HY, CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21
3	J:97579 Zhao R, Watt AJ, Li J, Luebke-Wheeler J, Morrisey EE, Duncan SA, GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol. 2005 Apr;25(7):2622-31
2	J:63117 Zukerberg LR, Patrick GN, Nikolic M, Humbert S, Wu CL, Lanier LM, Gertler FB, Vidal M, Van Etten RA, Tsai LH, Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron. 2000 Jun;26(3):633-46