Gene Expression Literature Summary

• Symbol: Apob
• Name: apolipoprotein B
• ID: MGI:88052

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8.5	E9	E9.5	E10.5	E11	E12	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	E19	E	P
Immunohistochemistry (section)			1	1																		3
In situ RNA (section)					1							1
Northern blot																						1
Western blot						1	1											1				4
RT-PCR	1	1	3	2		4	2	1	2	1	2	1	1	1	1	1	1	1	3	1	1	8
cDNA clones																						1
RNase protection			1								1								1			1
Primer Extension																						1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Apob  apolipoprotein B   (Synonyms: apob-100, apob-48)
Results	Reference
1	J:178985 Alvarez JI, Dodelet-Devillers A, Kebir H, Ifergan I, Fabre PJ, Terouz S, Sabbagh M, Wosik K, Bourbonniere L, Bernard M, van Horssen J, de Vries HE, Charron F, Prat A, The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science. 2011 Dec 23;334(6063):1727-31
2	J:114732 Blanc V, Henderson JO, Newberry EP, Kennedy S, Luo J, Davidson NO, Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality. Mol Cell Biol. 2005 Aug;25(16):7260-9
1	J:106993 Briancon N, Weiss MC, In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J. 2006 Mar 22;25(6):1253-62
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:64984 Duncan SA, Transcriptional regulation of liver development. Dev Dyn. 2000 Oct;219(2):131-42
1	J:202649 Evangelisti C, Bianco F, Pradella LM, Puliti A, Goldoni A, Sbrana I, Rossi M, Vargiolu M, Seri M, Romeo G, Stanghellini V, de Giorgio R, Bonora E, Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways. Neurogastroenterol Motil. 2012 Oct;24(10):e497-508
7*	J:84977 Farese RV Jr, Cases S, Ruland SL, Kayden HJ, Wong JS, Young SG, Hamilton RL, A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice. J Lipid Res. 1996 Feb;37(2):347-60
1*	J:23315 Farese RV Jr, Ruland SL, Flynn LM, Stokowski RP, Young SG, Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1774-8
2*	J:217130 Fossat N, Tourle K, Radziewic T, Barratt K, Liebhold D, Studdert JB, Power M, Jones V, Loebel DA, Tam PP, C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47. EMBO Rep. 2014 Aug;15(8):903-10
1	J:343810 Guo CG, Sun R, Wang X, Yuan Y, Xu Y, Li S, Sun X, Wang J, Hu X, Guo T, Chen XW, Xiao RP, Zhang X, Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion. Mol Metab. 2023 Nov 30;79:101847
1	J:338938 Kobayashi K, Iwasa K, Azuma-Suzuki R, Kawauchi T, Nabeshima YI, Feto-maternal cholesterol transport regulated by beta-Klotho-FGF15 axis is essential for fetal growth. Life Sci Alliance. 2023 Oct;6(10)
4	J:307827 Lindegaard ML, Nielsen LB, Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart. Metabolism. 2008 Jun;57(6):766-73
2	J:98265 Makita T, Duncan SA, Sucov HM, Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation. Dev Biol. 2005 Apr 1;280(1):59-72
1	J:175781 Makki N, Capecchi MR, Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development. Dev Biol. 2011 Sep 15;357(2):295-304
5*	J:92354 Mesli S, Javorschi S, Berard AM, Landry M, Priddle H, Kivlichan D, Smith AJ, Yen FT, Bihain BE, Darmon M, Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation. Eur J Biochem. 2004 Aug;271(15):3103-14
1*	J:280741 Morishita H, Zhao YG, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, Okazaki M, Li D, Mizushima N, A critical role of VMP1 in lipoprotein secretion. Elife. 2019 Sep 17;8:e48834
10	J:338187 Nargis T, Lin X, Giordano E, Ijaz L, Suhail S, Gurzenda EM, Kiefer D, Quadro L, Hanna N, Hussain MM, Characterization of lipoproteins in human placenta and fetal circulation as well as gestational changes in lipoprotein assembly and secretion in human and mouse placentas. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Jun 12;1868(9):159357
1	J:301025 Seelan RS, Mukhopadhyay P, Philipose J, Greene RM, Pisano MM, Gestational folate deficiency alters embryonic gene expression and cell function. Differentiation. 2020 Nov 27;117:1-15
2	J:138818 Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS 2nd, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I, Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. Mol Cell. 2008 Aug 22;31(4):531-43
7*	J:58384 Terasawa Y, Cases SJ, Wong JS, Jamil H, Jothi S, Traber MG, Packer L, Gordon DA, Hamilton RL, Farese RV Jr, Apolipoprotein B-related gene expression and ultrastructural characteristics of lipoprotein secretion in mouse yolk sac during embryonic development. J Lipid Res. 1999 Nov;40(11):1967-77
2*	J:130260 Van Dyck F, Braem CV, Chen Z, Declercq J, Deckers R, Kim BM, Ito S, Wu MK, Cohen DE, Dewerchin M, Derua R, Waelkens E, Fiette L, Roebroek A, Schuit F, Van de Ven WJ, Shivdasani RA, Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. Cell Metab. 2007 Nov;6(5):406-13
2	J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67
1	J:103454 Woda JM, Calzonetti T, Hilditch-Maguire P, Duyao MP, Conlon RA, MacDonald ME, Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo. BMC Dev Biol. 2005 Aug 18;5:17
1*	J:215393 Yamamoto S, Yamazaki T, Komazaki S, Yamashita T, Osaki M, Matsubayashi M, Kidoya H, Takakura N, Yamazaki D, Kakizawa S, Contribution of calumin to embryogenesis through participation in the endoplasmic reticulum-associated degradation activity. Dev Biol. 2014 Sep 1;393(1):33-43
2	J:334334 Zhang M, Salbaum JM, Jones S, Burk D, Kappen C, Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity. Front Cell Dev Biol. 2023;11:1073807