Gene Expression Literature Summary

• Symbol: Arc
• Name: activity regulated cytoskeletal-associated protein
• ID: MGI:88067

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8.5	E11.5	E13.5	E14.5	E15.5	E16	E17.5	E18	E18.5	P
Immunohistochemistry (section)						1							3
In situ RNA (section)					2	1	2	2	1	1	1	1	6
In situ RNA (whole mount)	1	1	1	1
Western blot						1							4
RT-PCR													2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Arc  activity regulated cytoskeletal-associated protein   (Synonyms: Arc3.1, arg 3.1)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
2	J:351708 Bjorklund GR, Rees KP, Balasubramanian K, Hewitt LT, Nishimura K, Newbern JM, Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning. Dis Model Mech. 2024 Jun 1;17(6)
1	J:319637 Cole JD, Sarabia Del Castillo J, Gut G, Gonzalez-Bohorquez D, Pelkmans L, Jessberger S, Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging. Elife. 2022 Jan 28;11:e68000
1	J:268552 Denaxa M, Neves G, Rabinowitz A, Kemlo S, Liodis P, Burrone J, Pachnis V, Modulation of Apoptosis Controls Inhibitory Interneuron Number in the Cortex. Cell Rep. 2018 Feb 13;22(7):1710-1721
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*	J:226892 Hammond VE, Gunnersen JM, Goh CP, Low LH, Hyakumura T, Tang MM, Britto JM, Putz U, Howitt JA, Tan SS, Ndfip1 is required for the development of pyramidal neuron dendrites and spines in the neocortex. Cereb Cortex. 2014 Dec;24(12):3289-300
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:209602 Li CL, Sathyamurthy A, Oldenborg A, Tank D, Ramanan N, SRF phosphorylation by glycogen synthase kinase-3 promotes axon growth in hippocampal neurons. J Neurosci. 2014 Mar 12;34(11):4027-42
1	J:352712 Lin CW, Cheng YC, Yang CH, Huang HS, Light activates Ube3a, an Angelman syndrome-associated gene, by mediating the chromatin structures during postnatal development of mouse retina. J Neurochem. 2023 Dec;167(6):766-777
4*	J:61449 Liu D, Bei D, Parmar H, Matus A, Activity-regulated, cytoskeleton-associated protein (Arc) is essential for visceral endoderm organization during early embryogenesis. Mech Dev. 2000 Apr;92(2):207-15
2	J:253948 Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD, Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016 Aug;97:1-14
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2*	J:221453 Matsunaga E, Nambu S, Oka M, Iriki A, Comparative analysis of developmentally regulated expressions of Gadd45a, Gadd45b, and Gadd45g in the mouse and marmoset cerebral cortex. Neuroscience. 2015 Jan 22;284:566-80
1*	J:209428 Ragancokova D, Rocca E, Oonk AM, Schulz H, Rohde E, Bednarsch J, Feenstra I, Pennings RJ, Wende H, Garratt AN, TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. J Clin Invest. 2014 Mar 3;124(3):1214-27
1	J:148808 Sawallisch C, Berhorster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ, The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem. 2009 Apr 3;284(14):9225-36
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:352085 Wang DC, Santos-Valencia F, Song JH, Franks KM, Luo L, Embryonically active piriform cortex neurons promote intracortical recurrent connectivity during development. Neuron. 2024 Jun 27;
1	J:230714 Xing L, Larsen RS, Bjorklund GR, Li X, Wu Y, Philpot BD, Snider WD, Newbern JM, Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex. Elife. 2016;5:e11123
1	J:326577 Zheng J, Suo L, Zhou Y, Jia L, Li J, Kuang Y, Cui D, Zhang X, Wu Q, Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner. J Mol Cell Biol. 2022 Jan 21;13(11):808-821