Symbol Name ID |
Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1 MGI:88283 |
Age | E2.5 | E3 | E3.5 | E4.5 | E8.5 | E9.5 | E10.5 | E11 | E11.5 | E12.5 | E13.5 | E14.5 | E15.5 | E16.5 | E17.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 3 | 2 | 2 | 1 | 3 | 3 | ||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 7 | 1 | 4 | 2 | 1 | 2 | |||||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | |||||||||||||
Western blot | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 3 | 2 | ||||||||||
RT-PCR | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | ||||||
cDNA clones | 1 |
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 (Synonyms: Cbp1, Cbp2, colligin, gp46, Hsp47, J6, Serpinh2) | |
Results | Reference |
3 | J:326354 Allegre N, Chauveau S, Dennis C, Renaud Y, Meistermann D, Estrella LV, Pouchin P, Cohen-Tannoudji M, David L, Chazaud C, NANOG initiates epiblast fate through the coordination of pluripotency genes expression. Nat Commun. 2022 Jun 21;13(1):3550 |
3* | J:51222 Bachner D, Ahrens M, Schroder D, Hoffmann A, Lauber J, Betat N, Steinert P, Flohe L, Gross G, Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn. 1998 Dec;213(4):398-411 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
1 | J:213432 Burns TA, Dours-Zimmermann MT, Zimmermann DR, Krug EL, Comte-Walters S, Reyes L, Davis MA, Schey KL, Schwacke JH, Kern CB, Mjaatvedt CH, Imbalanced expression of Vcan mRNA splice form proteins alters heart morphology and cellular protein profiles. PLoS One. 2014;9(2):e89133 |
1 | J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89 |
1* | J:89882 Hansen TV, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, Nielsen FC, Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice. Mol Cell Biol. 2004 May;24(10):4448-64 |
3* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
3* | J:307832 Kaji DA, Montero AM, Patel R, Huang AH, Transcriptional profiling of mESC-derived tendon and fibrocartilage cell fate switch. Nat Commun. 2021 Jul 9;12(1):4208 |
2* | J:358139 Kot A, Chun C, Martin JH, Wachtell D, Hudson D, Weis M, Marks H, Srivastava S, Eyre DR, Duran I, Zieba J, Krakow D, Loss of the long form of Plod2 phenocopies contractures of Bruck syndrome-osteogenesis imperfecta. J Bone Miner Res. 2024 Sep 2;39(9):1240-1252 |
1* | J:52895 Loones MT, Morange M, Hsp and chaperone distribution during endochondral bone development in mouse embryo. Cell Stress Chaperones. 1998 Dec;3(4):237-44 |
3* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
5 | J:93842 Marutani T, Yamamoto A, Nagai N, Kubota H, Nagata K, Accumulation of type IV collagen in dilated ER leads to apoptosis in Hsp47-knockout mouse embryos via induction of CHOP. J Cell Sci. 2004 Nov 15;117(Pt 24):5913-22 |
2 | J:197791 Masago Y, Hosoya A, Kawasaki K, Kawano S, Nasu A, Toguchida J, Fujita K, Nakamura H, Kondoh G, Nagata K, The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation. J Cell Sci. 2012 Mar 1;125(Pt 5):1118-28 |
12* | J:52896 Masuda H, Hosokawa N, Nagata K, Expression and localization of collagen-binding stress protein Hsp47 in mouse embryo development: comparison with types I and II collagen. Cell Stress Chaperones. 1998 Dec;3(4):256-64 |
2 | J:320375 Mirigian LS, Makareeva E, Mertz EL, Omari S, Roberts-Pilgrim AM, Oestreich AK, Phillips CL, Leikin S, Osteoblast Malfunction Caused by Cell Stress Response to Procollagen Misfolding in alpha2(I)-G610C Mouse Model of Osteogenesis Imperfecta. J Bone Miner Res. 2016 Aug;31(8):1608-1616 |
3 | J:64899 Nagai N, Hosokawa M, Itohara S, Adachi E, Matsushita T, Hosokawa N, Nagata K, Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J Cell Biol. 2000 Sep 18;150(6):1499-506 |
1* | J:198109 Oeschger FM, Wang WZ, Lee S, Garcia-Moreno F, Goffinet AM, Arbones ML, Rakic S, Molnar Z, Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59 |
2 | J:208289 Ohnishi Y, Huber W, Tsumura A, Kang M, Xenopoulos P, Kurimoto K, Oles AK, Arauzo-Bravo MJ, Saitou M, Hadjantonakis AK, Hiiragi T, Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages. Nat Cell Biol. 2014 Jan;16(1):27-37 |
1* | J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
22* | J:36919 Tanaka Y, Kobayashi K, Kita M, Masuda H, Kinoshita S, Nagata K, Imanishi J, Expression of 47 kDa heat shock protein (HSP47) during development of mouse cornea. Exp Eye Res. 1996 Oct;63(4):383-93 |
4* | J:83730 Wang G, Zhang J, Moskophidis D, Mivechi NF, Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis. 2003 May;36(1):48-61 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1 | J:150452 Zhou B, Ma Q, Kong SW, Hu Y, Campbell PH, McGowan FX, Ackerman KG, Wu B, Zhou B, Tevosian SG, Pu WT, Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart. J Clin Invest. 2009 Jun;119(6):1462-76 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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