Gene Expression Literature Summary

• Symbol: Cftr
• Name: cystic fibrosis transmembrane conductance regulator
• ID: MGI:88388

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5.5	E9.5	E10.5	E11.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E19	E20	P
Immunohistochemistry (section)	1				1	1	1		1		1	1	1		1	1	1	4
In situ RNA (section)								2	1			1		1				3
Immunohistochemistry (whole mount)																		1
Northern blot					1				1				1					1
Western blot																		1
RT-PCR		1	1	1	1				2	1	1	1	1					5
cDNA clones																		2
RNase protection											1							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cftr  cystic fibrosis transmembrane conductance regulator   (Synonyms: Abcc7)
Results	Reference
2*	J:38383 Bellusci S, Furuta Y, Rush MG, Henderson R, Winnier G, Hogan BL, Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development. 1997 Jan;124(1):53-63
2*	J:223752 Cai T, Yang L, Cai W, Guo S, Yu P, Li J, Hu X, Yan M, Shao Q, Jin Y, Sun ZS, Luo ZJ, Dysplastic spondylolysis is caused by mutations in the diastrophic dysplasia sulfate transporter gene. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8064-9
1	J:30592 Chianale J, Vollrath V, Wielandt AM, Miranda S, Gonzalez R, Fresno AM, Quintana C, Gonzalez S, Andrade L, Guzman S, Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine. Biochim Biophys Acta. 1995 Dec 27;1264(3):369-76
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:306246 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY, Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085
2	J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851
3*	J:63366 Kadison AS, Maldonado TS, Crisera CA, Longaker MT, Gittes GK, In vitro validation of duct differentiation in developing embryonic mouse pancreas. J Surg Res. 2000 May 15;90(2):126-30
8*	J:906 Kelley KA, Stamm S, Kozak CA, Expression and chromosome localization of the murine cystic fibrosis transmembrane conductance regulator. Genomics. 1992 Jun;13(2):381-8
1	J:306396 Kim YS, Fan R, Kremer L, Kuempel-Rink N, Mildner K, Zeuschner D, Hekking L, Stehling M, Bedzhov I, Deciphering epiblast lumenogenesis reveals proamniotic cavity control of embryo growth and patterning. Sci Adv. 2021 Mar;7(11)
1	J:338821 Li R, Wang T, Marquardt RM, Lydon JP, Wu SP, DeMayo FJ, TRIM28 modulates nuclear receptor signaling to regulate uterine function. Nat Commun. 2023 Aug 1;14(1):4605
1*	J:171626 Li S, Xiang M, Foxn4 influences alveologenesis during lung development. Dev Dyn. 2011 Jun;240(6):1512-7
10	J:175556 Merigo F, Mucignat-Caretta C, Cristofoletti M, Zancanaro C, Epithelial membrane transporters expression in the developing to adult mouse vomeronasal organ and olfactory mucosa. Dev Neurobiol. 2011 Oct;71(10):854-69
1	J:342643 Oh Y, Kasu M, Bottoms CJ, Douglas JC, Sekulovski N, Hayashi K, MacLean Ii JA, Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice. Biol Reprod. 2023 Oct 13;109(4):520-532
3	J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005
1	J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41
3	J:216308 Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S, CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway. J Cell Sci. 2014 Oct 15;127(Pt 20):4396-408
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
4	J:46368 White NL, Higgins CF, Trezise AE, Tissue-specific in vivo transcription start sites of the human and murine cystic fibrosis genes. Hum Mol Genet. 1998 Mar;7(3):363-9