Gene Expression Literature Summary

• Symbol: Col6a2
• Name: collagen, type VI, alpha 2
• ID: MGI:88460

28 matching records from 28 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5.5	E6.5	E7.5	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)		1	1	1	1	1	1	2		2		2	1	3	1	4	1	3	1				1			1	5
In situ RNA (section)	1	1	1					1	1	2			1	2		2		2	2	1				1		1	3
In situ RNA (whole mount)						1		1
In situ reporter (knock in)																											1
Western blot						1																					1
RT-PCR			1	2		2		1		3		3		4		2		1		1				3	1		6
RNase protection				1		1	1	1	1	1	1	1	1			1	1	1	1	1	1	1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Col6a2  collagen, type VI, alpha 2   (Synonyms: Col6a-2)
Results	Reference
1	J:185552 Acharya A, Baek ST, Huang G, Eskiocak B, Goetsch S, Sung CY, Banfi S, Sauer MF, Olsen GS, Duffield JS, Olson EN, Tallquist MD, The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors. Development. 2012 Jun;139(12):2139-49
1	J:204445 Andersen DC, Laborda J, Baladron V, Kassem M, Sheikh SP, Jensen CH, Dual role of delta-like 1 homolog (DLK1) in skeletal muscle development and adult muscle regeneration. Development. 2013 Sep;140(18):3743-53
1	J:224431 Besschetnova TY, Ichimura T, Katebi N, St Croix B, Bonventre JV, Olsen BR, Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol. 2015 Mar;42:56-73
1	J:141191 Braghetta P, Ferrari A, Fabbro C, Bizzotto D, Volpin D, Bonaldo P, Bressan GM, An enhancer required for transcription of the Col6a1 gene in muscle connective tissue is induced by signals released from muscle cells. Exp Cell Res. 2008 Nov 15;314(19):3508-18
1	J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
22*	J:35195 Dziadek M, Darling P, Bakker M, Overall M, Zhang RZ, Pan TC, Tillet E, Timpl R, Chu ML, Deposition of collagen VI in the extracellular matrix during mouse embryogenesis correlates with expression of the alpha 3(VI) subunit gene. Exp Cell Res. 1996 Aug 1;226(2):302-15
5	J:25133 Dziadek M, Darling P, Zhang RZ, Pan TC, Tillet E, Timpl R, Chu ML, Expression of collagen alpha 1(VI), alpha 2(VI), and alpha 3(VI) chains in the pregnant mouse uterus. Biol Reprod. 1995 Apr;52(4):885-94
1	J:158418 Endoh-Yamagami S, Karkar KM, May SR, Cobos I, Thwin MT, Long JE, Ashique AM, Zarbalis K, Rubenstein JL, Peterson AS, A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Dev Biol. 2010 Apr 1;340(1):41-53
2*	J:136559 Gara SK, Grumati P, Urciuolo A, Bonaldo P, Kobbe B, Koch M, Paulsson M, Wagener R, Three novel collagen VI chains with high homology to the alpha3 chain. J Biol Chem. 2008 Apr 18;283(16):10658-70
1*	J:80501 Gitton Y, Dahmane N, Baik S, Ruiz I Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML, A gene expression map of human chromosome 21 orthologues in the mouse. Nature. 2002 Dec 5;420(6915):586-90
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*	J:89882 Hansen TV, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, Nielsen FC, Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice. Mol Cell Biol. 2004 May;24(10):4448-64
1	J:352715 Kang HS, Grimm SA, Liao XH, Jetten AM, GLIS3 expression in the thyroid gland in relation to TSH signaling and regulation of gene expression. Cell Mol Life Sci. 2024 Jan 28;81(1):65
2*	J:111788 Kiyozumi D, Sugimoto N, Sekiguchi K, Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11981-6
34*	J:46232 Klewer SE, Krob SL, Kolker SJ, Kitten GT, Expression of type VI collagen in the developing mouse heart. Dev Dyn. 1998 Mar;211(3):248-55
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:113292 Lechner BE, Lim JH, Mercado ML, Fallon JR, Developmental regulation of biglycan expression in muscle and tendon. Muscle Nerve. 2006 Sep;34(3):347-55
1	J:306136 Manti M, Pui HP, Edstrom S, Risal S, Lu H, Lindgren E, Ohlsson C, Jerlhag E, Benrick A, Deng Q, Stener-Victorin E, Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. FASEB J. 2020 Nov;34(11):14440-14457
1	J:64899 Nagai N, Hosokawa M, Itohara S, Adachi E, Matsushita T, Hosokawa N, Nagata K, Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J Cell Biol. 2000 Sep 18;150(6):1499-506
5*	J:317548 Nishida S, Yoshizaki H, Yasui Y, Kuwahara T, Kiyokawa E, Kohno M, Collagen VI suppresses fibronectin-induced enteric neural crest cell migration by downregulation of focal adhesion proteins. Biochem Biophys Res Commun. 2018 Jan 1;495(1):1461-1467
3	J:230306 Odelin G, Faure E, Kober F, Maurel-Zaffran C, Theron A, Coulpier F, Guillet B, Bernard M, Avierinos JF, Charnay P, Topilko P, Zaffran S, Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes. Cardiovasc Res. 2014 Dec 1;104(3):443-55
7*	J:80502 Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A, Human chromosome 21 gene expression atlas in the mouse. Nature. 2002 Dec 5;420(6915):582-6
1	J:92613 Smyth I, Du X, Taylor MS, Justice MJ, Beutler B, Jackson IJ, The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13560-5
4	J:229828 Soret R, Mennetrey M, Bergeron KF, Dariel A, Neunlist M, Grunder F, Faure C, Silversides DW, Pilon N, A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease. J Clin Invest. 2015 Dec;125(12):4483-96
1*	J:283448 Sun SC, Ma D, Li MY, Zhang RX, Huang C, Huang HJ, Xie YZ, Wang ZJ, Liu J, Cai DC, Liu CX, Yang Q, Bao FX, Gong XL, Li JR, Hui Z, Wei XF, Zhong JM, Zhou WJ, Shang X, Zhang C, Liu XG, Tang BS, Xiong F, Xu XM, Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease. Brain. 2019 Aug 1;142(8):2215-2229
5*	J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76
1	J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28
1	J:83746 Vrontou S, Petrou P, Meyer BI, Galanopoulos VK, Imai K, Yanagi M, Chowdhury K, Scambler PJ, Chalepakis G, Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice. Nat Genet. 2003 Jun;34(2):209-14