Gene Expression Literature Summary

• Symbol: Col6a3
• Name: collagen, type VI, alpha 3
• ID: MGI:88461

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5.5	E6.5	E7.5	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)		1	1	1	1	1	1	2		2		2	1	3	1	5	1	3	1		1		1		1	6
In situ RNA (section)	1	1	1					1	1	2			1	2		3		3	1	2				2	1	2
In situ RNA (whole mount)								1				1
Western blot																					1					2
RT-PCR			1	1		1		1		2		2		2		2		1						1	1	6
cDNA clones																										1
RNase protection				1		1	1	1	1	1	1	1	1			1	1	1	1	1	1	1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Col6a3  collagen, type VI, alpha 3   (Synonyms: Col6a-3)
Results	Reference
1*	J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:224431 Besschetnova TY, Ichimura T, Katebi N, St Croix B, Bonventre JV, Olsen BR, Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol. 2015 Mar;42:56-73
1	J:141191 Braghetta P, Ferrari A, Fabbro C, Bizzotto D, Volpin D, Bonaldo P, Bressan GM, An enhancer required for transcription of the Col6a1 gene in muscle connective tissue is induced by signals released from muscle cells. Exp Cell Res. 2008 Nov 15;314(19):3508-18
1	J:169713 Diao H, Aplin JD, Xiao S, Chun J, Li Z, Chen S, Ye X, Altered spatiotemporal expression of collagen types I, III, IV, and VI in Lpar3-deficient peri-implantation mouse uterus. Biol Reprod. 2011 Feb;84(2):255-65
22*	J:35195 Dziadek M, Darling P, Bakker M, Overall M, Zhang RZ, Pan TC, Tillet E, Timpl R, Chu ML, Deposition of collagen VI in the extracellular matrix during mouse embryogenesis correlates with expression of the alpha 3(VI) subunit gene. Exp Cell Res. 1996 Aug 1;226(2):302-15
5	J:25133 Dziadek M, Darling P, Zhang RZ, Pan TC, Tillet E, Timpl R, Chu ML, Expression of collagen alpha 1(VI), alpha 2(VI), and alpha 3(VI) chains in the pregnant mouse uterus. Biol Reprod. 1995 Apr;52(4):885-94
2	J:329983 Fidalgo MF, Fonseca CG, Caldas P, Raposo AA, Balboni T, Henao-Misikova L, Grosso AR, Vasconcelos FF, Franco CA, Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes. Life Sci Alliance. 2022 Dec;5(12):e202201554
2	J:138755 Fitzgerald J, Rich C, Zhou FH, Hansen U, Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI). J Biol Chem. 2008 Jul 18;283(29):20170-80
4	J:173953 Gara SK, Grumati P, Squarzoni S, Sabatelli P, Urciuolo A, Bonaldo P, Paulsson M, Wagener R, Differential and restricted expression of novel collagen VI chains in mouse. Matrix Biol. 2011 May;30(4):248-57
2*	J:136559 Gara SK, Grumati P, Urciuolo A, Bonaldo P, Kobbe B, Koch M, Paulsson M, Wagener R, Three novel collagen VI chains with high homology to the alpha3 chain. J Biol Chem. 2008 Apr 18;283(16):10658-70
3*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*	J:89882 Hansen TV, Hammer NA, Nielsen J, Madsen M, Dalbaeck C, Wewer UM, Christiansen J, Nielsen FC, Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice. Mol Cell Biol. 2004 May;24(10):4448-64
2	J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132
2*	J:111788 Kiyozumi D, Sugimoto N, Sekiguchi K, Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11981-6
34*	J:46232 Klewer SE, Krob SL, Kolker SJ, Kitten GT, Expression of type VI collagen in the developing mouse heart. Dev Dyn. 1998 Mar;211(3):248-55
1	J:113292 Lechner BE, Lim JH, Mercado ML, Fallon JR, Developmental regulation of biglycan expression in muscle and tendon. Muscle Nerve. 2006 Sep;34(3):347-55
1	J:306136 Manti M, Pui HP, Edstrom S, Risal S, Lu H, Lindgren E, Ohlsson C, Jerlhag E, Benrick A, Deng Q, Stener-Victorin E, Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. FASEB J. 2020 Nov;34(11):14440-14457
5*	J:317548 Nishida S, Yoshizaki H, Yasui Y, Kuwahara T, Kiyokawa E, Kohno M, Collagen VI suppresses fibronectin-induced enteric neural crest cell migration by downregulation of focal adhesion proteins. Biochem Biophys Res Commun. 2018 Jan 1;495(1):1461-1467
3*	J:208903 Pan TC, Zhang RZ, Arita M, Bogdanovich S, Adams SM, Gara SK, Wagener R, Khurana TS, Birk DE, Chu ML, A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16. J Biol Chem. 2014 Apr 11;289(15):10293-307
1	J:92613 Smyth I, Du X, Taylor MS, Justice MJ, Beutler B, Jackson IJ, The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13560-5
4	J:229828 Soret R, Mennetrey M, Bergeron KF, Dariel A, Neunlist M, Grunder F, Faure C, Silversides DW, Pilon N, A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease. J Clin Invest. 2015 Dec;125(12):4483-96
4*	J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76
1	J:83746 Vrontou S, Petrou P, Meyer BI, Galanopoulos VK, Imai K, Yanagi M, Chowdhury K, Scambler PJ, Chalepakis G, Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice. Nat Genet. 2003 Jun;34(2):209-14