Gene Expression Literature Summary

• Symbol: Crk
• Name: v-crk avian sarcoma virus CT10 oncogene homolog
• ID: MGI:88508

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9	E10.5	E11.5	E12.5	E14.5	E15.5	E16	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)		2	1	1	1					1
In situ RNA (section)			1			1						1
In situ RNA (whole mount)		1				1
Northern blot											1	1
Western blot		1		1	1			2				7
RT-PCR	1				1				1			1
cDNA clones							2
RNase protection												1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Crk  v-crk avian sarcoma virus CT10 oncogene homolog   (Synonyms: Crk-I, Crk-II, Crk-III, Crko, proto-oncogene c-crk)
Results	Reference
3	J:273460 Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X, Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 2018 Jan 23;7:e32586
5*	J:29533 de Jong R, Haataja L, Voncken JW, Heisterkamp N, Groffen J, Tyrosine phosphorylation of murine Crkl. Oncogene. 1995 Oct 19;11(8):1469-74
1	J:145031 Feng L, Cooper JA, Dual functions of Dab1 during brain development. Mol Cell Biol. 2009 Jan;29(2):324-32
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*	J:165470 Hallock PT, Xu CF, Park TJ, Neubert TA, Curran T, Burden SJ, Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Genes Dev. 2010 Nov 1;24(21):2451-61
1*	J:112731 Huang J, Sakai R, Furuichi T, The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons. Mol Biol Cell. 2006 Jul;17(7):3187-96
1*	J:283745 Imamoto A, Ki S, Li L, Iwamoto K, Maruthamuthu V, Devany J, Lu O, Kanazawa T, Zhang S, Yamada T, Hirayama A, Fukuda S, Suzuki Y, Okada M, Essential role of the Crk family-dosage in DiGeorge-like anomaly and metabolic homeostasis. Life Sci Alliance. 2020 Feb;3(2)
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:39581 Margolis B, Silvennoinen O, Comoglio F, Roonprapunt C, Skolnik E, Ullrich A, Schlessinger J, High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8894-8
2	J:18775 Ogawa S, Toyoshima H, Kozutsumi H, Hagiwara K, Sakai R, Tanaka T, Hirano N, Mano H, Yazaki Y, Hirai H, The C-terminal SH3 domain of the mouse c-Crk protein negatively regulates tyrosine-phosphorylation of Crk associated p130 in rat 3Y1 cells. Oncogene. 1994 Jun;9(6):1669-78
4*	J:84932 Prosser S, Sorokina E, Pratt P, Sorokin A, CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins. Oncogene. 2003 Jul 31;22(31):4799-806
1	J:166211 Qiu Z, Cang Y, Goff SP, Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum. J Neurosci. 2010 Oct 27;30(43):14430-9
1	J:165694 Roselli S, Wallez Y, Wang L, Vervoort V, Pasquale EB, The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas. Cell Signal. 2010 Nov;22(11):1745-52
1	J:217671 Sathyamurthy A, Yin DM, Barik A, Shen C, Bean JC, Figueiredo D, She JX, Xiong WC, Mei L, ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Development. 2015 Feb 1;142(3):522-32
1*	J:253683 Schwartz B, Marks M, Wittler L, Werber M, Wahrisch S, Nordheim A, Herrmann BG, Grote P, SRF is essential for mesodermal cell migration during elongation of the embryonic body axis. Mech Dev. 2014 Aug;133:23-35
1	J:326381 Shi L, Racedo SE, Diacou A, Park T, Zhou B, Morrow BE, Crk and Crkl have shared functions in neural crest cells for cardiac outflow tract septation and vascular smooth muscle differentiation. Hum Mol Genet. 2022 Apr 22;31(8):1197-1215
1	J:229358 Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU, Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Exp Eye Res. 2014 Apr;121:130-42
1*	J:84075 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A, 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul;34(3):274-85
1	J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683
1	J:163165 Yano M, Hayakawa-Yano Y, Mele A, Darnell RB, Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron. 2010 Jun 24;66(6):848-58