Gene Expression Literature Summary

• Symbol: Crybb2
• Name: crystallin, beta B2
• ID: MGI:88519

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E14.5	E15	E15.5	E16.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)			1	1	1				4
In situ RNA (section)		1							1
Western blot					1				2
RT-PCR	1	1	1	1	1	1	1	1	5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Crybb2  crystallin, beta B2   (Synonyms: Aey2, betaB2-crystallin, Cryb-2)
Results	Reference
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4*	J:136138 Ganguly K, Favor J, Neuhauser-Klaus A, Sandulache R, Puk O, Beckers J, Horsch M, Schadler S, Vogt Weisenhorn D, Wurst W, Graw J, Novel allele of crybb2 in the mouse and its expression in the brain. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1533-41
3*	J:332312 Jiao X, Kabir F, Irum B, Khan AO, Wang Q, Li D, Khan AA, Husnain T, Akram J, Riazuddin S, Hejtmancik JF, Riazuddin SA, A Common Ancestral Mutation in CRYBB3 Identified in Multiple Consanguineous Families with Congenital Cataracts. PLoS One. 2016;11(6):e0157005
2	J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134
3	J:95535 Min JN, Zhang Y, Moskophidis D, Mivechi NF, Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis. 2004 Dec;40(4):205-17
1	J:168996 Ren S, Liu T, Jia C, Qi X, Wang Y, Physiological expression of lens alpha-, beta-, and gamma-crystallins in murine and human corneas. Mol Vis. 2010;16:2745-52
2	J:37334 Reneker LW, Overbeek PA, Lens-specific expression of PDGF-A alters lens growth and development. Dev Biol. 1996 Dec 15;180(2):554-65
2*	J:56583 Ring BZ, Cordes SP, Overbeek PA, Barsh GS, Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development. 2000 Jan;127(2):307-17
5	J:201986 Sun M, Holter SM, Stepan J, Garrett L, Genius J, Kremmer E, Hrabe de Angelis M, Wurst W, Lie DC, Bally-Cuif L, Eder M, Rujescu D, Graw J, Crybb2 coding for betaB2-crystallin affects sensorimotor gating and hippocampal function. Mamm Genome. 2013 Oct;24(9-10):333-48
1	J:269956 Wada K, Matsushima Y, Tada T, Hasegawa S, Obara Y, Yoshizawa Y, Takahashi G, Hiai H, Shimanuki M, Suzuki S, Saitou J, Yamamoto N, Ichikawa M, Watanabe K, Kikkawa Y, Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice. PLoS One. 2014;9(10):e111432
1	J:178731 Xie Q, Cvekl A, The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71