Gene Expression Literature Summary

• Symbol: Ctsb
• Name: cathepsin B
• ID: MGI:88561

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4	E5.5	E6	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	P
Immunohistochemistry (section)	1		1		1	1				1				1						1		2				5
In situ RNA (section)		1			1	1	1		1	1	1	1	1	2	1	1	2		1	3	1	1	1		1	3
Northern blot					1	1	1	1	1		1		1													2
Western blot						1		1																		5
RT-PCR					1													1
cDNA clones				1
RNase protection					1				1				1				1			1				1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ctsb  cathepsin B   (Synonyms: CB)
Results	Reference
11	J:43064 Afonso S, Romagnano L, Babiarz B, The expression and function of cystatin C and cathepsin B and cathepsin L during mouse embryo implantation and placentation. Development. 1997 Sep;124(17):3415-25
12*	J:58845 Afonso S, Romagnano L, Babiarz B, Expression of cathepsin proteinases by mouse trophoblast in vivo and in vitro. Dev Dyn. 1999 Dec;216(4-5):374-84
3	J:183077 Amarante-Paffaro AM, Hoshida MS, Yokota S, Goncalves CR, Joazeiro PP, Bevilacqua E, Yamada AT, Localization of cathepsins D and B at the maternal-fetal interface and the invasiveness of the trophoblast during the postimplantation period in the mouse. Cells Tissues Organs. 2011;193(6):417-25
2*	J:315095 Bando Y, Yamamoto M, Sakiyama K, Inoue K, Takizawa S, Owada Y, Iseki S, Kondo H, Amano O, Expression of epidermal fatty acid binding protein (E-FABP) in septoclasts in the growth plate cartilage of mice. J Mol Histol. 2014 Oct;45(5):507-18
11*	J:173463 Bejarano-Escobar R, Holguin-Arevalo MS, Montero JA, Francisco-Morcillo J, Martin-Partido G, Macrophage and microglia ontogeny in the mouse visual system can be traced by the expression of Cathepsins B and D. Dev Dyn. 2011 Jul;240(7):1841-55
1	J:305611 Castroflorio E, den Hoed J, Svistunova D, Finelli MJ, Cebrian-Serrano A, Corrochano S, Bassett AR, Davies B, Oliver PL, The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour. Cell Mol Life Sci. 2021 Apr;78(7):3503-3524
1	J:32190 Dardik A, Smith RM, Schultz RM, Colocalization of transforming growth factor-alpha and a functional epidermal growth factor receptor (EGFR) to the inner cell mass and preferential localization of the EGFR on the basolateral surface of the trophectoderm in the mouse blastocyst. Dev Biol. 1992 Dec;154(2):396-409
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:346909 Ha HT, Liu S, Nguyen XT, Vo LK, Leong NC, Nguyen DT, Balamurugan S, Lim PY, Wu Y, Seong E, Nguyen TQ, Oh J, Wenk MR, Cazenave-Gassiot A, Yapici Z, Ong WY, Burmeister M, Nguyen LN, Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models. JCI Insight. 2024 Mar 7;:e175462
1	J:187732 Kawamura N, Sun-Wada GH, Aoyama M, Harada A, Takasuga S, Sasaki T, Wada Y, Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos. Nat Commun. 2012 Sep 18;3:1071
1	J:222854 Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gomez-Galan M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T, Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015 Jun;18(6):826-35
2	J:274409 Masuda T, Sankowski R, Staszewski O, Bottcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grun D, Priller J, Stadelmann C, Prinz M, Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature. 2019 Feb;566(7744):388-392
1	J:233172 Mehanna S, Suzuki C, Shibata M, Sunabori T, Imanaka T, Araki K, Yamamura K, Uchiyama Y, Ohmuraya M, Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity. Biochem Biophys Res Commun. 2016 Jan 15;469(3):405-11
2	J:154471 Natale DR, Hemberger M, Hughes M, Cross JC, Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate. Dev Biol. 2009 Nov 1;335(1):120-31
1	J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12
1	J:325090 Sakashita H, Bando Y, Nagasaka A, Sakiyama K, Onozawa G, Taira F, Ogasawara Y, Owada Y, Sakashita H, Amano O, Spatial and chronological localization of septoclasts in the mouse Meckel's cartilage. Histochem Cell Biol. 2022 May;157(5):569-580
1*	J:85207 Shirahama-Noda K, Yamamoto A, Sugihara K, Hashimoto N, Asano M, Nishimura M, Hara-Nishimura I, Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice. J Biol Chem. 2003 Aug 29;278(35):33194-9
7*	J:59171 Sol-Church K, Shipley J, Beckman DA, Mason RW, Expression of cysteine proteases in extraembryonic tissues during mouse embryogenesis. Arch Biochem Biophys. 1999 Dec 15;372(2):375-81
3	J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11;
2*	J:116987 Zuzarte-Luis V, Montero JA, Kawakami Y, Izpisua-Belmonte JC, Hurle JM, Lysosomal cathepsins in embryonic programmed cell death. Dev Biol. 2007 Jan 1;301(1):205-17