Gene Expression Literature Summary

• Symbol: Cyp1a1
• Name: cytochrome P450, family 1, subfamily a, polypeptide 1
• ID: MGI:88588

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1.5	E3.5	E7	E10.5	E11	E12.5	E13	E13.5	E14.5	E15	E16.5	E17	E18	E18.5	P
In situ RNA (section)					1					1		1				1
Western blot															1
RT-PCR	1	1	1	2		2	1	1	1	2	2		3	1	1	6
cDNA clones																1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cyp1a1  cytochrome P450, family 1, subfamily a, polypeptide 1   (Synonyms: cytochrome P450 subfamily I, polypeptide 1, P450-1)
Results	Reference
4*	J:55992 Abbott BD, Schmid JE, Brown JG, Wood CR, White RD, Buckalew AR, Held GA, RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone. Toxicol Sci. 1999 Jan;47(1):76-85
5*	J:83483 Choudhary D, Jansson I, Schenkman JB, Sarfarazi M, Stoilov I, Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. Arch Biochem Biophys. 2003 Jun 1;414(1):91-100
5*	J:96956 Choudhary D, Jansson I, Stoilov I, Sarfarazi M, Schenkman JB, Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. Arch Biochem Biophys. 2005 Apr 1;436(1):50-61
4*	J:50816 Dey A, Nebert DW, Markedly increased constitutive CYP1A1 mRNA levels in the fertilized ovum of the mouse. Biochem Biophys Res Commun. 1998 Oct 20;251(2):657-61
1	J:267157 Flaveny C, Perdew GH, Miller CA 3rd, The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo. Toxicol Lett. 2009 Aug 25;189(1):57-62
1	J:294716 Liang ZS, Cimino I, Yalcin B, Raghupathy N, Vancollie VE, Ibarra-Soria X, Firth HV, Rimmington D, Farooqi IS, Lelliott CJ, Munger SC, O'Rahilly S, Ferguson-Smith AC, Coll AP, Logan DW, Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity. PLoS Genet. 2020 Sep;16(9):e1008916
3	J:103326 Nishizawa H, Imanishi S, Manabe N, Effects of exposure in utero to bisphenol a on the expression of aryl hydrocarbon receptor, related factors, and xenobiotic metabolizing enzymes in murine embryos. J Reprod Dev. 2005 Oct;51(5):593-605
2	J:174028 Salbaum JM, Kruger C, Zhang X, Delahaye NA, Pavlinkova G, Burk DH, Kappen C, Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy. Diabetologia. 2011 Jul;54(7):1909-20
2	J:142539 Vezina CM, Allgeier SH, Moore RW, Lin TM, Bemis JC, Hardin HA, Gasiewicz TA, Peterson RE, Dioxin causes ventral prostate agenesis by disrupting dorsoventral patterning in developing mouse prostate. Toxicol Sci. 2008 Dec;106(2):488-96
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:94671 Xu M, Miller MS, Determination of murine fetal Cyp1a1 and 1b1 expression by real-time fluorescence reverse transcription-polymerase chain reaction. Toxicol Appl Pharmacol. 2004 Dec 15;201(3):295-302
1	J:277277 Zieman AG, Poll BG, Ma J, Coulombe PA, Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. Hum Mol Genet. 2019 Jul 1;28(13):2255-2270