Gene Expression Literature Summary

• Symbol: Tcof1
• Name: treacle ribosome biogenesis factor 1
• ID: MGI:892003

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E13.5	E14.5	E15	E17	E	P
Immunohistochemistry (section)									1
In situ RNA (section)											1
Immunohistochemistry (whole mount)														1
In situ RNA (whole mount)		1	1	1	1	1	1
In situ reporter (knock in)			1		1
Northern blot	1							1				1	1		1
RT-PCR				1	1	1	1	1				1			1
cDNA clones			1			1	1			1					1
RNase protection							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tcof1  treacle ribosome biogenesis factor 1   (Synonyms: treacle)
Results	Reference
1	J:340778 Dash S, Lamb MC, Lange JJ, McKinney MC, Tsuchiya D, Guo F, Zhao X, Corbin TJ, Kirkman M, Delventhal K, Moore EL, McKinney S, Shiang R, Trainor PA, rRNA transcription is integral to phase separation and maintenance of nucleolar structure. PLoS Genet. 2023 Aug;19(8):e1010854
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
13*	J:40192 Dixon J, Hovanes K, Shiang R, Dixon MJ, Sequence analysis, identification of evolutionary conserved motifs and expression analysis of murine tcof1 provide further evidence for a potential function for the gene and its human homologue, TCOF1. Hum Mol Genet. 1997 May;6(5):727-37
3	J:332795 Falcon KT, Watt KEN, Dash S, Zhao R, Sakai D, Moore EL, Fitriasari S, Childers M, Sardiu ME, Swanson S, Tsuchiya D, Unruh J, Bugarinovic G, Li L, Shiang R, Achilleos A, Dixon J, Dixon MJ, Trainor PA, Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2116974119
2*	J:211289 Fantauzzo KA, Soriano P, PI3K-mediated PDGFRalpha signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways. Genes Dev. 2014 May 1;28(9):1005-17
6*	J:42919 Paznekas WA, Zhang N, Gridley T, Jabs EW, Mouse TCOF1 is expressed widely, has motifs conserved in nucleolar phosphoproteins, and maps to chromosome 18. Biochem Biophys Res Commun. 1997 Sep 8;238(1):1-6
1	J:183605 Sakai D, Dixon J, Dixon MJ, Trainor PA, Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. PLoS Genet. 2012 Mar;8(3):e1002566
2*	J:91489 Valdez BC, Henning D, So RB, Dixon J, Dixon MJ, The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10709-14