Symbol Name ID |
Rap1b
RAS related protein 1b MGI:894315 |
Age | E10.5 | E11 | E11.5 | E13.5 | E16 | E17 | E17.5 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | 1 | 3 | ||||
In situ RNA (section) | 1 | |||||||||
Western blot | 1 | 1 | 1 | 6 | ||||||
RT-PCR | 1 | 1 | 1 | 1 |
Rap1b RAS related protein 1b (Synonyms: 2810443E11Rik) | |
Results | Reference |
2 | J:288966 Chang S, Lu X, Wang S, Wang Z, Huo J, Huang J, Shangguan S, Li S, Zou J, Bao Y, Guo J, Wang F, Niu B, Zhang T, Qiu Z, Wu J, Wang L, The effect of folic acid deficiency on FGF pathway via Brachyury regulation in neural tube defects. FASEB J. 2019 Apr;33(4):4688-4702 |
1 | J:333325 Cheng Q, Wu J, Xia Y, Cheng Q, Zhao Y, Zhu P, Zhang W, Zhang S, Zhang L, Yuan Y, Li C, Chen G, Xue B, Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. Mol Brain. 2023 Feb 13;16(1):24 |
1 | J:178484 Maddala R, Chauhan BK, Walker C, Zheng Y, Robinson ML, Lang RA, Rao PV, Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011 Dec 1;360(1):30-43 |
7* | J:226036 Maddala R, Nagendran T, Lang RA, Morozov A, Rao PV, Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91 |
2 | J:316180 Maruyama T, Jiang M, Abbott A, Yu HI, Huang Q, Chrzanowska-Wodnicka M, Chen EI, Hsu W, Rap1b Is an Effector of Axin2 Regulating Crosstalk of Signaling Pathways During Skeletal Development. J Bone Miner Res. 2017 Sep;32(9):1816-1828 |
1* | J:242457 Qiao S, Homayouni R, Dab2IP Regulates Neuronal Positioning, Rap1 Activity and Integrin Signaling in the Developing Cortex. Dev Neurosci. 2015;37(2):131-41 |
2 | J:241040 Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW, Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex. 2017 Feb 01;27(2):1253-1269 |
1 | J:269939 Stefanini L, Lee RH, Paul DS, O'Shaughnessy EC, Ghalloussi D, Jones CI, Boulaftali Y, Poe KO, Piatt R, Kechele DO, Caron KM, Hahn KM, Gibbins JM, Bergmeier W, Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood. 2018 Nov 1;132(18):1951-1962 |
1 | J:221899 Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W, RASA3 is a critical inhibitor of RAP1-dependent platelet activation. J Clin Invest. 2015 Apr;125(4):1419-32 |
2 | J:172908 Traver S, Bidot C, Spassky N, Baltauss T, De Tand MF, Thomas JL, Zalc B, Janoueix-Lerosey I, Gunzburg JD, RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Biochem J. 2000 Aug 15;350 Pt 1:19-29 |
2* | J:321065 Utreras E, Henriquez D, Contreras-Vallejos E, Olmos C, Di Genova A, Maass A, Kulkarni AB, Gonzalez-Billault C, Cdk5 regulates Rap1 activity. Neurochem Int. 2013 May;62(6):848-53 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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