Gene Expression Literature Summary

• Symbol: Dlx4
• Name: distal-less homeobox 4
• ID: MGI:94904

26 matching records from 26 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9	E9.5	E10	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17	E17.5	E18.5	E	P
Immunohistochemistry (section)	1	2	1	2		2			1
In situ RNA (section)					1	2	2	1	2	1	1	1	2	1		3
Immunohistochemistry (whole mount)				1
In situ RNA (whole mount)		3		6	2	1	1	1	2	1			1		1
RT-PCR		1		1	2										1	3
cDNA clones					1											2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dlx4  distal-less homeobox 4   (Synonyms: DII D, Dlx-4, Dlx7)
Results	Reference
3	J:83694 Andrews GL, Yun K, Rubenstein JL, Mastick GS, Dlx transcription factors regulate differentiation of dopaminergic neurons of the ventral thalamus. Mol Cell Neurosci. 2003 May;23(1):107-20
2	J:306174 Coubrough ML, Bendall AJ, Impaired nuclear import of mammalian Dlx4 proteins as a consequence of rapid sequence divergence. Exp Cell Res. 2006 Nov 15;312(19):3880-91
2	J:139748 Dinger ME, Amaral PP, Mercer TR, Pang KC, Bruce SJ, Gardiner BB, Askarian-Amiri ME, Ru K, Solda G, Simons C, Sunkin SM, Crowe ML, Grimmond SM, Perkins AC, Mattick JS, Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation. Genome Res. 2008 Sep;18(9):1433-45
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1	J:80081 Gritli-Linde A, Bei M, Maas R, Zhang XM, Linde A, McMahon AP, Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development. 2002 Dec;129(23):5323-37
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:254511 Inoue K, Hirose M, Inoue H, Hatanaka Y, Honda A, Hasegawa A, Mochida K, Ogura A, The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development. Cell Rep. 2017 May 2;19(5):949-956
1	J:139700 Jeong J, Li X, McEvilly RJ, Rosenfeld MG, Lufkin T, Rubenstein JL, Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs. Development. 2008 Sep;135(17):2905-16
1	J:262096 Johnson JA, Watson JK, Nikolic MZ, Rawlins EL, Fank1 and Jazf1 promote multiciliated cell differentiation in the mouse airway epithelium. Biol Open. 2018 Apr 16;7(4):bio033944
1*	J:94411 Kelly RG, Jerome-Majewska LA, Papaioannou VE, The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis. Hum Mol Genet. 2004 Nov 15;13(22):2829-40
3	J:81581 Liu C, Nakamura E, Knezevic V, Hunter S, Thompson K, Mackem S, A role for the mesenchymal T-box gene Brachyury in AER formation during limb development. Development. 2003 Apr;130(7):1327-37
2	J:37712 Nakamura S, Stock DW, Wydner KL, Bollekens JA, Takeshita K, Nagai BM, Chiba S, Kitamura T, Freeland TM, Zhao Z, Minowada J, Lawrence JB, Weiss KM, Ruddle FH, Genomic analysis of a new mammalian distal-less gene: Dlx7. Genomics. 1996 Dec 15;38(3):314-24
1	J:345597 Quilez S, Dumontier E, Baim C, Kam J, Cloutier JF, Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects. Front Cell Dev Biol. 2024;12:1256465
1	J:117075 Radoja N, Guerrini L, Lo Iacono N, Merlo GR, Costanzo A, Weinberg WC, La Mantia G, Calabro V, Morasso MI, Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias. Development. 2007 Jan;134(1):13-8
4*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1	J:69870 Skogh C, Eriksson C, Kokaia M, Meijer XC, Wahlberg LU, Wictorin K, Campbell K, Generation of regionally specified neurons in expanded glial cultures derived from the mouse and human lateral ganglionic eminence. Mol Cell Neurosci. 2001 May;17(5):811-20
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:116684 Tiveron MC, Rossel M, Moepps B, Zhang YL, Seidenfaden R, Favor J, Konig N, Cremer H, Molecular interaction between projection neuron precursors and invading interneurons via stromal-derived factor 1 (CXCL12)/CXCR4 signaling in the cortical subventricular zone/intermediate zone. J Neurosci. 2006 Dec 20;26(51):13273-8
1	J:52596 Toresson H, Mata de Urquiza A, Fagerstrom C, Perlmann T, Campbell K, Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation. Development. 1999 Mar;126(6):1317-26
1	J:270530 Van Otterloo E, Li H, Jones KL, Williams T, AP-2alpha and AP-2beta cooperatively orchestrate homeobox gene expression during branchial arch patterning. Development. 2018 Jan 25;145(2):dev157438
1*	J:293200 Vanyai HK, Garnham A, May RE, McRae HM, Collin C, Wilcox S, Smyth GK, Thomas T, Voss AK, MOZ directs the distal-less homeobox gene expression program during craniofacial development. Development. 2019 Jul 24;146(14):dev175042
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
4*	J:224001 Wu D, Mandal S, Choi A, Anderson A, Prochazkova M, Perry H, Gil-Da-Silva-Lopes VL, Lao R, Wan E, Tang PL, Kwok PY, Klein O, Zhuan B, Slavotinek AM, DLX4 is associated with orofacial clefting and abnormal jaw development. Hum Mol Genet. 2015 Aug 1;24(15):4340-52
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
10*	J:62179 Zhao Z, Stock D, Buchanan A, Weiss K, Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5