Gene Expression Literature Summary

• Symbol: Dmpk
• Name: dystrophia myotonica-protein kinase
• ID: MGI:94906

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6	E7	E8	E9	E10	E10.5	E11	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E18.5	E19	E	P
Immunohistochemistry (section)						1			1		1		1	1
In situ RNA (section)						1					1		1	1		1	1
In situ RNA (whole mount)	1	1	1	1	1	1	1
In situ reporter (knock in)																	1
Northern blot																	1
Western blot																	1
RT-PCR						1		2	1	1	1	1	1	2			7
RNase protection													1		1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dmpk  dystrophia myotonica-protein kinase   (Synonyms: DM, Dm15)
Results	Reference
1	J:308882 Dennison BJC, Larson ED, Fu R, Mo J, Fantauzzo KA, Srsf3 mediates alternative RNA splicing downstream of PDGFRalpha signaling in the facial mesenchyme. Development. 2021 Jul 15;148(14):dev199448
5*	J:207560 Gladman JT, Mandal M, Srinivasan V, Mahadevan MS, Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1). PLoS One. 2013;8(9):e72907
5*	J:138797 Harmon EB, Harmon ML, Larsen TD, Paulson AF, Perryman MB, Myotonic dystrophy protein kinase is expressed in embryonic myocytes and is required for myotube formation. Dev Dyn. 2008 Sep;237(9):2353-66
2*	J:40220 Heath SK, Carne S, Hoyle C, Johnson KJ, Wells DJ, Characterisation of expression of mDMAHP, a homeodomain-encoding gene at the murine DM locus. Hum Mol Genet. 1997 May;6(5):651-7
3*	J:23408 Jansen G, Bartolomei M, Kalscheuer V, Merkx G, Wormskamp N, Mariman E, Smeets D, Ropers HH, Wieringa B, No imprinting involved in the expression of DM-kinase mRNAs in mouse and human tissues. Hum Mol Genet. 1993 Aug;2(8):1221-7
6	J:33711 Jansen G, Groenen PJ, Bachner D, Jap PH, Coerwinkel M, Oerlemans F, van den Broek W, Gohlsch B, Pette D, Plomp JJ, Molenaar PC, Nederhoff MG, van Echteld CJ, Dekker M, Berns A, Hameister H, Wieringa B, Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice [see comments]. Nat Genet. 1996 Jul;13(3):316-24
1*	J:97257 Kaliman P, Catalucci D, Lam JT, Kondo R, Gutierrez JC, Reddy S, Palacin M, Zorzano A, Chien KR, Ruiz-Lozano P, Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum. J Biol Chem. 2005 Mar 4;280(9):8016-21
3*	J:85713 Kanadia RN, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS, Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns. 2003 Aug;3(4):459-62
5*	J:43635 Laurent A, Pinset C, Aurade F, Vidaud M, Montarras D, Expression of myotonic dystrophy protein kinase gene during in vivo and in vitro mouse myogenesis. Cell Mol Biol (Noisy-Le-Grand). 1997 Sep;43(6):881-8
1	J:316483 Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML, Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Dev Dyn. 2021 Dec;250(12):1778-1795
5	J:338401 Nutter CA, Kidd BM, Carter HA, Hamel JI, Mackie PM, Kumbkarni N, Davenport ML, Tuyn DM, Gopinath A, Creigh PD, Sznajder LJ, Wang ET, Ranum LPW, Khoshbouei H, Day JW, Sampson JB, Prokop S, Swanson MS, Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1. Brain. 2023 May 5;
1	J:199127 Poulos MG, Batra R, Li M, Yuan Y, Zhang C, Darnell RB, Swanson MS, Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. Hum Mol Genet. 2013 Sep 1;22(17):3547-58
1	J:233532 Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterle S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L, Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 May 17;35(10):1077-97
2*	J:171727 Schlesinger J, Schueler M, Grunert M, Fischer JJ, Zhang Q, Krueger T, Lange M, Tonjes M, Dunkel I, Sperling SR, The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs. PLoS Genet. 2011 Feb;7(2):e1001313