Symbol Name ID |
Dnmt1
DNA methyltransferase 1 MGI:94912 |
Age | E0.5 | E1 | E1.5 | E2 | E2.5 | E3 | E3.5 | E4 | E4.5 | E5.5 | E7.5 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 4 | 4 | 1 | 3 | 2 | 3 | 2 | 2 | 1 | 2 | 4 | 1 | 6 | 1 | 17 | ||||||||
In situ RNA (section) | 1 | 2 | 1 | 1 | 3 | 2 | 5 | 2 | 3 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 8 | |||||||||||||||||
Immunohistochemistry (whole mount) | 4 | 4 | 1 | 3 | 3 | 3 | 3 | 1 | 6 | |||||||||||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | ||||||||||||||||||||||||||||||
Northern blot | 1 | 2 | 1 | 1 | 1 | 1 | 4 | |||||||||||||||||||||||||||
Western blot | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | 4 | 1 | 3 | 1 | 2 | 5 | 1 | 2 | 1 | 3 | 1 | 18 | ||||||||||||||
RT-PCR | 7 | 7 | 4 | 8 | 7 | 6 | 5 | 3 | 2 | 3 | 3 | 4 | 1 | 2 | 3 | 3 | 1 | 4 | 4 | 1 | 2 | 1 | 1 | 5 | 1 | 23 | ||||||||
cDNA clones | 1 | 1 | 1 | 1 | 1 | 3 |
Dnmt1 DNA methyltransferase 1 (Synonyms: Cxxc9, Dnmt1o, MommeD2, MTase) | |
Results | Reference |
1* | J:176660 Abler LL, Keil KP, Mehta V, Joshi PS, Schmitz CT, Vezina CM, A high-resolution molecular atlas of the fetal mouse lower urogenital tract. Dev Dyn. 2011 Oct;240(10):2364-77 |
1* | J:271018 Auclair G, Borgel J, Sanz LA, Vallet J, Guibert S, Dumas M, Cavelier P, Girardot M, Forne T, Feil R, Weber M, EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos. Genome Res. 2016 Feb;26(2):192-202 |
1* | J:29257 Beard C, Li E, Jaenisch R, Loss of methylation activates Xist in somatic but not in embryonic cells. Genes Dev. 1995 Oct 1;9(19):2325-34 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
7 | J:203762 Burton A, Muller J, Tu S, Padilla-Longoria P, Guccione E, Torres-Padilla ME, Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep. 2013 Nov 14;5(3):687-701 |
5* | J:100438 Chen HW, Chen JJ, Yu SL, Li HN, Yang PC, Su CM, Au HK, Chang CW, Chien LW, Chen CS, Tzeng CR, Transcriptome analysis in blastocyst hatching by cDNA microarray. Hum Reprod. 2005 Sep;20(9):2492-501 |
13* | J:135338 Cirio MC, Ratnam S, Ding F, Reinhart B, Navara C, Chaillet JR, Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints. BMC Dev Biol. 2008;8:9 |
1 | J:321806 Dave JM, Chakraborty R, Ntokou A, Saito J, Saddouk FZ, Feng Z, Misra A, Tellides G, Riemer RK, Urban Z, Kinnear C, Ellis J, Mital S, Mecham R, Martin KA, Greif DM, JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency. J Clin Invest. 2022 Mar 1;132(5):e142338 |
4 | J:224084 Elliott EN, Sheaffer KL, Schug J, Stappenbeck TS, Kaestner KH, Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium. Development. 2015 Jun 15;142(12):2163-72 |
1* | J:266522 Elsen GE, Bedogni F, Hodge RD, Bammler TK, MacDonald JW, Lindtner S, Rubenstein JLR, Hevner RF, The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6--> Tbr2--> Tbr1. Front Neurosci. 2018;12:571 |
5 | J:17720 Goto K, Numata M, Komura JI, Ono T, Bestor TH, Kondo H, Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation. 1994 Apr;56(1-2):39-44 |
6* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
7* | J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85 |
2 | J:93248 Hamatani T, Falco G, Carter MG, Akutsu H, Stagg CA, Sharov AA, Dudekula DB, VanBuren V, Ko MS, Age-associated alteration of gene expression patterns in mouse oocytes. Hum Mol Genet. 2004 Nov 1;13(19):2263-78 |
1 | J:259618 Hatazawa Y, Ono Y, Hirose Y, Kanai S, Fujii NL, Machida S, Nishino I, Shimizu T, Okano M, Kamei Y, Ogawa Y, Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration. FASEB J. 2018 Mar;32(3):1452-1467 |
6 | J:264903 Hoang TV, Horowitz ER, Chaffee BR, Qi P, Flake RE, Bruney DG, Rasor BJ, Rosalez SE, Wagner BD, Robinson ML, Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity. Epigenetics. 2017 Jan 2;12(1):27-40 |
7* | J:68455 Howell CY, Bestor TH, Ding F, Latham KE, Mertineit C, Trasler JM, Chaillet JR, Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene. Cell. 2001 Mar 23;104(6):829-38 |
5 | J:99563 Jeong KS, Park JH, Lee S, The analysis of X-chromosome inactivation-related gene expression from single mouse embryo with sex-determination. Biochem Biophys Res Commun. 2005 Aug 5;333(3):803-7 |
2 | J:266277 Joseph DB, Chandrashekar AS, Abler LL, Chu LF, Thomson JA, Mendelsohn C, Vezina CM, In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8394-8399 |
1* | J:273083 Joseph DB, Chandrashekar AS, Abler LL, Chu LF, Thomson JA, Vezina CM, Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds. Dev Biol. 2019 Mar 15;447(2):157-169 |
2* | J:218173 Keil KP, Abler LL, Laporta J, Altmann HM, Yang B, Jarrard DF, Hernandez LL, Vezina CM, Androgen receptor DNA methylation regulates the timing and androgen sensitivity of mouse prostate ductal development. Dev Biol. 2014 Dec 15;396(2):237-45 |
3* | J:202864 Keil KP, Altmann HM, Mehta V, Abler LL, Elton EA, Vezina CM, Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract. Gene Expr Patterns. 2013 Dec;13(8):413-24 |
1 | J:314906 Khang R, Jo A, Kang H, Kim H, Kwag E, Lee JY, Koo O, Park J, Kim HK, Jo DG, Hwang I, Ahn JY, Lee Y, Choi JY, Lee YS, Shin JH, Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. Sci Rep. 2021 Nov 23;11(1):22745 |
1 | J:286844 Kim J, Kim K, Mo JS, Lee Y, Atm deficiency in the DNA polymerase beta null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation. Nucleic Acids Res. 2020 Apr 17;48(7):3678-3691 |
3 | J:169234 Kim JD, Kim H, Ekram MB, Yu S, Faulk C, Kim J, Rex1/Zfp42 as an epigenetic regulator for genomic imprinting. Hum Mol Genet. 2011 Apr 1;20(7):1353-62 |
1 | J:282322 Ko HR, Hwang I, Jin EJ, Yun T, Ryu D, Kang JS, Park KW, Shin JH, Cho SW, Lee KH, Ye K, Ahn JY, Roles of ErbB3-binding protein 1 (EBP1) in embryonic development and gene-silencing control. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24852-24860 |
7* | J:97776 Ko YG, Nishino K, Hattori N, Arai Y, Tanaka S, Shiota K, Stage-by-stage change in DNA methylation status of Dnmt1 locus during mouse early development. J Biol Chem. 2005 Mar 11;280(10):9627-34 |
11 | J:92186 La Salle S, Mertineit C, Taketo T, Moens PB, Bestor TH, Trasler JM, Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells. Dev Biol. 2004 Apr 15;268(2):403-15 |
3* | J:265473 Leng F, Yu J, Zhang C, Alejo S, Hoang N, Sun H, Lu F, Zhang H, Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4(DCAF5) ubiquitin ligase. Nat Commun. 2018 Apr 24;9(1):1641 |
1 | J:1157 Li E, Bestor TH, Jaenisch R, Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 1992 Jun 12;69(6):915-26 |
5 | J:191599 Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM, Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol. 2012 Dec;132(12):2681-90 |
1 | J:335823 Li Q, Lu J, Yin X, Chang Y, Wang C, Yan M, Feng L, Cheng Y, Gao Y, Xu B, Zhang Y, Wang Y, Cui G, Xu L, Sun Y, Zeng R, Li Y, Jing N, Xu GL, Wu L, Tang F, Li J, Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation. Nat Commun. 2023 May 22;14(1):2922 |
1* | J:135330 Li X, Kato Y, Tsuji Y, Tsunoda Y, The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts. Cloning Stem Cells. 2008 Mar;10(1):133-42 |
5 | J:280419 Liberti DC, Zepp JA, Bartoni CA, Liberti KH, Zhou S, Lu M, Morley MP, Morrisey EE, Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate. Dev Biol. 2019 Oct 15;454(2):108-117 |
2 | J:279721 Linscott ML, Chung WCJ, TET1 regulates fibroblast growth factor 8 transcription in gonadotropin releasing hormone neurons. PLoS One. 2019;14(7):e0220530 |
2 | J:131948 Liu L, Bailey SM, Okuka M, Munoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL, Telomere lengthening early in development. Nat Cell Biol. 2007 Dec;9(12):1436-41 |
1 | J:346631 Liu L, Zhang X, Geng HR, Qiao YN, Gui YH, Zhao JY, High paternal homocysteine causes ventricular septal defects in mouse offspring. iScience. 2024 Apr 19;27(4):109447 |
4* | J:104974 MacDonald JL, Gin CS, Roskams AJ, Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development. Dev Biol. 2005 Dec 15;288(2):461-73 |
3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
2 | J:275254 Mahadevan S, Sathappan V, Utama B, Lorenzo I, Kaskar K, Van den Veyver IB, Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming. Sci Rep. 2017 Mar 20;7:44667 |
1 | J:161421 Mann W, Haaf T, Single cell RT-PCR on mouse embryos: a general approach for developmental biology. Methods Mol Biol. 2010;630:3-12 |
1 | J:306136 Manti M, Pui HP, Edstrom S, Risal S, Lu H, Lindgren E, Ohlsson C, Jerlhag E, Benrick A, Deng Q, Stener-Victorin E, Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. FASEB J. 2020 Nov;34(11):14440-14457 |
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1 | J:231817 Matsumoto S, Kiryu-Seo S, Kiyama H, Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development. J Neurosci. 2016 Apr 27;36(17):4744-57 |
4* | J:145796 May A, Kirchner R, Muller H, Hartmann P, El Hajj N, Tresch A, Zechner U, Mann W, Haaf T, Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres. Biol Reprod. 2009 Jan;80(1):194-202 |
1 | J:261809 Mayer C, Hafemeister C, Bandler RC, Machold R, Batista Brito R, Jaglin X, Allaway K, Butler A, Fishell G, Satija R, Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462 |
1 | J:341543 Meng TG, Guo JN, Zhu L, Yin Y, Wang F, Han ZM, Lei L, Ma XS, Xue Y, Yue W, Nie XQ, Zhao ZH, Zhang HY, Sun SM, Ouyang YC, Hou Y, Schatten H, Ju Z, Ou XH, Wang ZB, Wong CCL, Li Z, Sun QY, NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition. Adv Sci (Weinh). 2023 Sep;10(27):e2301940 |
7* | J:46642 Mertineit C, Yoder JA, Taketo T, Laird DW, Trasler JM, Bestor TH, Sex-specific exons control DNA methyltransferase in mammalian germ cells. Development. 1998 Mar;125(5):889-97 |
1 | J:235473 Moyon S, Huynh JL, Dutta D, Zhang F, Ma D, Yoo S, Lawrence R, Wegner M, John GR, Emery B, Lubetzki C, Franklin RJM, Fan G, Zhu J, Dupree JL, Casaccia P, Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage. Cell Rep. 2016 Apr 26;15(4):748-760 |
14 | J:180117 Nasonkin IO, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A, Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011 Jul 1;519(10):1914-30 |
7* | J:50138 Niederreither K, Harbers M, Chambon P, Dolle P, Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis. Oncogene. 1998 Sep 24;17(12):1577-85 |
1 | J:234092 Noguchi H, Murao N, Kimura A, Matsuda T, Namihira M, Nakashima K, DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus. J Neurosci. 2016 Jun 1;36(22):6050-68 |
1 | J:279449 Nowialis P, Lopusna K, Opavska J, Haney SL, Abraham A, Sheng P, Riva A, Natarajan A, Guryanova O, Simpson M, Hlady R, Xie M, Opavsky R, Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions. Nat Commun. 2019 Sep 26;10(1):4374 |
1* | J:203737 Oda M, Oxley D, Dean W, Reik W, Regulation of lineage specific DNA hypomethylation in mouse trophectoderm. PLoS One. 2013;8(6):e68846 |
1 | J:116773 Oda M, Yamagiwa A, Yamamoto S, Nakayama T, Tsumura A, Sasaki H, Nakao K, Li E, Okano M, DNA methylation regulates long-range gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner. Genes Dev. 2006 Dec 15;20(24):3382-94 |
3* | J:284860 Okashita N, Kuroki S, Maeda R, Tachibana M, TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression. Sci Rep. 2019 Sep 17;9(1):13462 |
3 | J:269416 Pensold D, Symmank J, Hahn A, Lingner T, Salinas-Riester G, Downie BR, Ludewig F, Rotzsch A, Haag N, Andreas N, Schubert K, Hubner CA, Pieler T, Zimmer G, The DNA Methyltransferase 1 (DNMT1) Controls the Shape and Dynamics of Migrating POA-Derived Interneurons Fated for the Murine Cerebral Cortex. Cereb Cortex. 2017 Dec 1;27(12):5696-5714 |
1 | J:92421 Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM, NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science. 2004 Aug 20;305(5687):1157-9 |
19 | J:76510 Ratnam S, Mertineit C, Ding F, Howell CY, Clarke HJ, Bestor TH, Chaillet JR, Trasler JM, Dynamics of Dnmt1 methyltransferase expression and intracellular localization during oogenesis and preimplantation development. Dev Biol. 2002 May 15;245(2):304-14 |
2 | J:312335 Reyes-Aguirre LI, Lamas M, Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Muller Glia Dedifferentiation in a Murine Model of Retinal Injury. Front Neurosci. 2016;10:523 |
4 | J:309713 Rhee KD, Yu J, Zhao CY, Fan G, Yang XJ, Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival. Cell Death Dis. 2012 Nov 22;3:e427 |
3 | J:213445 Rutledge CE, Lau HT, Mangan H, Hardy LL, Sunnotel O, Guo F, MacNicol AM, Walsh CP, Lees-Murdock DJ, Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements. PLoS One. 2014;9(2):e88385 |
7* | J:133257 Sajedi E, Gaston-Massuet C, Andoniadou CL, Signore M, Hurd PJ, Dattani M, Martinez-Barbera JP, DNMT1 interacts with the developmental transcriptional repressor HESX1. Biochim Biophys Acta. 2008 Jan;1783(1):131-43 |
9 | J:79935 Sakai Y, Suetake I, Itoh K, Mizugaki M, Tajima S, Yamashina S, Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo. Cell Struct Funct. 2001 Dec;26(6):685-91 |
4 | J:223970 Shaffer B, McGraw S, Xiao SC, Chan D, Trasler J, Chaillet JR, The DNMT1 intrinsically disordered domain regulates genomic methylation during development. Genetics. 2015 Feb;199(2):533-41 |
4 | J:162462 Shah MY, Vasanthakumar A, Barnes NY, Figueroa ME, Kamp A, Hendrick C, Ostler KR, Davis EM, Lin S, Anastasi J, Le Beau MM, Moskowitz IP, Melnick A, Pytel P, Godley LA, DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Res. 2010 Jul 15;70(14):5840-50 |
1 | J:279154 Shen J, Wang C, Li D, Xu T, Myers J, Ashton JM, Wang T, Zuscik MJ, McAlinden A, O'Keefe RJ, DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. JCI Insight. 2017 Jun 15;2(12) |
2 | J:156018 Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S, The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell. 2009 Dec;17(6):775-87 |
2 | J:129049 Takebayashi S, Tamura T, Matsuoka C, Okano M, Major and essential role for the DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions. Mol Cell Biol. 2007 Dec;27(23):8243-58 |
2* | J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208 |
5* | J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23 |
11* | J:33741 Trasler JM, Trasler DG, Bestor TH, Li E, Ghibu F, DNA methyltransferase in normal and Dnmtn/Dnmtn mouse embryos. Dev Dyn. 1996 Jul;206(3):239-47 |
4 | J:344644 Ulschmid CM, Sun MR, Jabbarpour CR, Steward AC, Rivera-Gonzalez KS, Cao J, Martin AA, Barnes M, Wicklund L, Madrid A, Papale LA, Joseph DB, Vezina CM, Alisch RS, Lipinski RJ, Disruption of DNA methylation-mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice. Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2317668121 |
7* | J:255612 Uysal F, Ozturk S, Akkoyunlu G, DNMT1, DNMT3A and DNMT3B proteins are differently expressed in mouse oocytes and early embryos. J Mol Histol. 2017 Dec;48(5-6):417-426 |
3 | J:273751 Uysal F, Ozturk S, Akkoyunlu G, Superovulation alters DNA methyltransferase protein expression in mouse oocytes and early embryos. J Assist Reprod Genet. 2018 Mar;35(3):503-513 |
2* | J:160567 Velasco G, Hube F, Rollin J, Neuillet D, Philippe C, Bouzinba-Segard H, Galvani A, Viegas-Pequignot E, Francastel C, Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9281-6 |
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1* | J:50167 Walsh CP, Chaillet JR, Bestor TH, Transcription of IAP endogenous retroviruses is constrained by cytosine methylation [letter]. Nat Genet. 1998 Oct;20(2):116-7 |
1 | J:144527 Wang J, Hevi S, Kurash JK, Lei H, Gay F, Bajko J, Su H, Sun W, Chang H, Xu G, Gaudet F, Li E, Chen T, The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet. 2009 Jan;41(1):125-9 |
4 | J:310870 Wang W, Zhao X, Shao Y, Duan X, Wang Y, Li J, Li J, Li D, Li X, Wong J, Mutation-induced DNMT1 cleavage drives neurodegenerative disease. Sci Adv. 2021 Sep 3;7(36):eabe8511 |
2* | J:296647 Wanner N, Vornweg J, Combes A, Wilson S, Plappert J, Rafflenbeul G, Puelles VG, Rahman RU, Liwinski T, Lindner S, Grahammer F, Kretz O, Wlodek ME, Romano T, Moritz KM, Boerries M, Busch H, Bonn S, Little MH, Bechtel-Walz W, Huber TB, DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation. J Am Soc Nephrol. 2019 Jan;30(1):63-78 |
1* | J:93502 Watanabe D, Suetake I, Tajima S, Hanaoka K, Expression of Dnmt3b in mouse hematopoietic progenitor cells and spermatogonia at specific stages. Gene Expr Patterns. 2004 Nov;5(1):43-9 |
1* | J:162781 Weaver JR, Sarkisian G, Krapp C, Mager J, Mann MR, Bartolomei MS, Domain-specific response of imprinted genes to reduced DNMT1. Mol Cell Biol. 2010 Aug;30(16):3916-28 |
6* | J:320811 Wu F, Wu Q, Li D, Zhang Y, Wang R, Liu Y, Li W, Oct4 regulates DNA methyltransferase 1 transcription by direct binding of the regulatory element. Cell Mol Biol Lett. 2018;23:39 |
2 | J:333868 Yan R, Cheng X, Gu C, Xu Y, Long X, Zhai J, Sun F, Qian J, Du Y, Wang H, Guo F, Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development. Nat Genet. 2023 Jan;55(1):130-143 |
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3* | J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48 |
2 | J:350675 Yu V, Yong F, Marta A, Khadayate S, Osakwe A, Bhattacharya S, Varghese SS, Chabosseau P, Tabibi SM, Chen K, Georgiadou E, Parveen N, Suleiman M, Stamoulis Z, Marselli L, De Luca C, Tesi M, Ostinelli G, Delgadillo-Silva L, Wu X, Hatanaka Y, Montoya A, Elliott J, Patel B, Demchenko N, Whilding C, Hajkova P, Shliaha P, Kramer H, Ali Y, Marchetti P, Sladek R, Dhawan S, Withers DJ, Rutter GA, Millership SJ, Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity. Diabetologia. 2024 Jun;67(6):1079-1094 |
1* | J:138573 Yurttas P, Vitale AM, Fitzhenry RJ, Cohen-Gould L, Wu W, Gossen JA, Coonrod SA, Role for PADI6 and the cytoplasmic lattices in ribosomal storage in oocytes and translational control in the early mouse embryo. Development. 2008 Aug;135(15):2627-36 |
4 | J:247285 Zhang D, Wu B, Wang P, Wang Y, Lu P, Nechiporuk T, Floss T, Greally JM, Zheng D, Zhou B, Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts. Nucleic Acids Res. 2017 Apr 07;45(6):3102-3115 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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