Gene Expression Literature Summary

• Symbol: Eef2
• Name: eukaryotic translation elongation factor 2
• ID: MGI:95288

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E7.5	E9.5	E11.5	E12.5	E13	E13.5	E14.5	E15	E15.5	E16.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)						1			1
In situ RNA (section)									1
In situ RNA (whole mount)				1
Northern blot							1			1				1		1
Western blot	1	1			1	2		1	2		2	1	1		1	4
RT-PCR																1
cDNA clones			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Eef2  eukaryotic translation elongation factor 2   (Synonyms: Ef-2)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
8	J:349721 Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosario M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC, Protein translation rate determines neocortical neuron fate. Nat Commun. 2024 Jun 7;15(1):4879
1	J:271287 Fakruddin M, Wei FY, Suzuki T, Asano K, Kaieda T, Omori A, Izumi R, Fujimura A, Kaitsuka T, Miyata K, Araki K, Oike Y, Scorrano L, Suzuki T, Tomizawa K, Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease. Cell Rep. 2018 Jan 9;22(2):482-496
4	J:154032 Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F, Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. PLoS One. 2009;4(10):e7641
3	J:357241 Iyyappan R, Aleshkina D, Ming H, Dvoran M, Kakavand K, Jansova D, Del Llano E, Gahurova L, Bruce AW, Masek T, Pospisek M, Horvat F, Kubelka M, Jiang Z, Susor A, The translational oscillation in oocyte and early embryo development. Nucleic Acids Res. 2023 Dec 11;51(22):12076-12091
1	J:314906 Khang R, Jo A, Kang H, Kim H, Kwag E, Lee JY, Koo O, Park J, Kim HK, Jo DG, Hwang I, Ahn JY, Lee Y, Choi JY, Lee YS, Shin JH, Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. Sci Rep. 2021 Nov 23;11(1):22745
1	J:50869 Ko MSH, Threat TA, Wang X, Horton JH, Cui Y, Pryor E, Paris J , Wells-Smith J , Kitchen JR , Rowe LB , Eppig J , Satoh T , Brant L , Fujiwara H , Yotsumoto S , Nakashima H, Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
3	J:216392 Kraushar ML, Thompson K, Wijeratne HR, Viljetic B, Sakers K, Marson JW, Kontoyiannis DL, Buyske S, Hart RP, Rasin MR, Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3815-24
4*	J:80962 Sakagami H, Nishimura H, Saito R, Kondo H, Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in developing mouse brain. Neurosci Lett. 2002 Sep 13;330(1):41-4
1	J:347602 Shi Y, Huang D, Song C, Cao R, Wang Z, Wang D, Zhao L, Xu X, Lu C, Xiong F, Zhao H, Li S, Zhou Q, Luo S, Hu D, Zhang Y, Wang C, Shen Y, Su W, Wu Y, Schmitz K, Wei S, Song W, Diphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects. Nat Commun. 2024 Apr 26;15(1):3301