Gene Expression Literature Summary

• Symbol: Eif1a
• Name: eukaryotic translation initiation factor 1A
• ID: MGI:95298

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E2.5	E3	E3.5	E4	E7.5	E9.5	E10.5	E14.5	E	P
Immunohistochemistry (section)														1
Immunohistochemistry (whole mount)	1	1		1	1	1	1							1
Northern blot	3	1	1	2	1	1		1				1		3
Western blot										1
RT-PCR	6	7	1	1	1		1			1				4
cDNA clones									2		1		1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Eif1a  eukaryotic translation initiation factor 1A   (Synonyms: Ef1a, Eftu, eIF-1A, Eif4c)
Results	Reference
1	J:228732 Berg JM, Lee C, Chen L, Galvan L, Cepeda C, Chen JY, Penagarikano O, Stein JL, Li A, Oguro-Ando A, Miller JA, Vashisht AA, Starks ME, Kite EP, Tam E, Gdalyahu A, Al-Sharif NB, Burkett ZD, White SA, Fears SC, Levine MS, Wohlschlegel JA, Geschwind DH, JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron. 2015 Dec 16;88(6):1173-91
3	J:32035 Davis W Jr, De Sousa PA, Schultz RM, Transient expression of translation initiation factor eIF-4C during the 2-cell stage of the preimplantation mouse embryo: identification by mRNA differential display and the role of DNA replication in zygotic gene activation. Dev Biol. 1996 Mar 15;174(2):190-201
3*	J:50486 Davis W Jr, Schultz RM, Molecular cloning and expression of the mouse translation initiation factor eIF-1A. Nucleic Acids Res. 1998 Oct 15;26(20):4739-47
8*	J:50182 De Sousa PA, Watson AJ, Schultz RM, Transient expression of a translation initiation factor is conservatively associated with embryonic gene activation in murine and bovine embryos. Biol Reprod. 1998 Oct;59(4):969-77
1	J:50869 Ko MSH, Threat TA, Wang X, Horton JH, Cui Y, Pryor E, Paris J , Wells-Smith J , Kitchen JR , Rowe LB , Eppig J , Satoh T , Brant L , Fujiwara H , Yotsumoto S , Nakashima H, Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
2*	J:349160 Lamacova L, Jansova D, Jiang Z, Dvoran M, Aleshkina D, Iyyappan R, Jindrova A, Fan HY, Jiao Y, Susor A, CPEB3 Maintains Developmental Competence of the Oocyte. Cells. 2024 May 16;13(10)
8*	J:314924 Liu Y, Sun J, Su Y, Lin J, Lv C, Mo K, Xu S, Wang S, Nuclear-localized eukaryotic translation initiation factor 1A is involved in mouse preimplantation embryo development. J Mol Histol. 2021 Oct;52(5):965-973
1	J:78343 Loebel DA, O'Rourke MP, Steiner KA, Banyer J, Tam PP, Isolation of differentially expressed genes from wild-type and Twist mutant mouse limb buds. Genesis. 2002 Jul;33(3):103-13
1	J:64067 Nebigil CG, Choi DS, Dierich A, Hickel P, Le Meur M, Messaddeq N, Launay JM, Maroteaux L, Serotonin 2B receptor is required for heart development. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9508-13
3	J:282460 Rong Y, Ji SY, Zhu YZ, Wu YW, Shen L, Fan HY, ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation. Nucleic Acids Res. 2019 Dec 2;47(21):11387-11402
3*	J:171441 Rother F, Shmidt T, Popova E, Krivokharchenko A, Hugel S, Vilianovich L, Ridders M, Tenner K, Alenina N, Kohler M, Hartmann E, Bader M, Importin alpha7 Is Essential for Zygotic Genome Activation and Early Mouse Development. PLoS One. 2011;6(3):e18310
1	J:233532 Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterle S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L, Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 May 17;35(10):1077-97
1*	J:330032 Shi F, Xu Y, Zhang S, Fu Z, Yu Q, Zhang S, Sun M, Zhao X, Feng X, Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice. FASEB J. 2022 Aug;36(8):e22445
1	J:1572 Varmuza S, Tate P, Isolation of epiblast-specific cDNA clones by differential hybridization with polymerase chain reaction-amplified probes derived from single embryos. Mol Reprod Dev. 1992 Aug;32(4):339-48
1	J:153804 Vijayaraj P, Kroger C, Reuter U, Windoffer R, Leube RE, Magin TM, Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor. J Cell Biol. 2009 Oct 19;187(2):175-84
7	J:71069 Wang Q, Chung YG, deVries WN, Struwe M, Latham KE, Role of protein synthesis in the development of a transcriptionally permissive state in one-cell stage mouse embryos. Biol Reprod. 2001 Sep;65(3):748-54
2	J:40650 Wang Q, Latham KE, Requirement for protein synthesis during embryonic genome activation in mice. Mol Reprod Dev. 1997 Jul;47(3):265-70
1	J:91975 Yuasa S, Nakajima M, Aizawa H, Sahara N, Koizumi K, Sakai T, Usami M, Kobayashi S, Kuroyanagi H, Mori H, Koseki H, Shirasawa T, Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice. J Neurosci Res. 2002 Nov 1;70(3):501-13
2*	J:330334 Zhang H, Jiang JC, Wu YW, Yu YS, Wang HN, Ding NZ, Fan HY, The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance. Development. 2022 Oct 1;149(19):dev200497