Gene Expression Literature Summary

• Symbol: Emx2
• Name: empty spiracles homeobox 2
• ID: MGI:95388

225 matching records from 225 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)				1	1	1	1	5		4	1	6	1	2		1	1	1		3			1	2		2	3
In situ RNA (section)				1	2	8	5	13	2	23	2	44	2	23	3	17	2	16	1	9	2	4		8	1	4	9
In situ RNA (whole mount)	1	1	7	19	11	27	2	23	6	13	1	11		6	1	1		4		1				2		1	1
Northern blot					2	1				1		1		1		1		1			1
Western blot										1		1		1				1									1
RT-PCR				2	2	2		6	2	5	2	12	2	5	3	9		2		3			1	2			5
cDNA clones									1	1																	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Emx2  empty spiracles homeobox 2   (Synonyms: Pdo)
Results	Reference
2	J:43308 Acampora D, Avantaggiato V, Tuorto F, Simeone A, Genetic control of brain morphogenesis through Otx gene dosage requirement. Development. 1997 Sep;124(18):3639-50
1*	J:29276 Acampora D, Mazan S, Lallemand Y, Avantaggiato V, Maury M, Simeone A, Brulet P, Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development. 1995 Oct;121(10):3279-90
1*	J:79833 Agarwala S, Ragsdale CW, A role for midbrain arcs in nucleogenesis. Development. 2002 Dec;129(24):5779-88
1	J:106499 Airik R, Bussen M, Singh MK, Petry M, Kispert A, Tbx18 regulates the development of the ureteral mesenchyme. J Clin Invest. 2006 Mar;116(3):663-74
1*	J:30828 Ang SL, Jin O, Rhinn M, Daigle N, Stevenson L, Rossant J, A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development. 1996 Jan;122(1):243-52
2*	J:134435 Anselme I, Laclef C, Lanaud M, Ruther U, Schneider-Maunoury S, Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes. Dev Biol. 2007 Apr 1;304(1):208-20
1*	J:184980 Assimacopoulos S, Kao T, Issa NP, Grove EA, Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography. J Neurosci. 2012 May 23;32(21):7191-201
4	J:96233 Backman M, Machon O, Mygland L, van den Bout CJ, Zhong W, Taketo MM, Krauss S, Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol. 2005 Mar 1;279(1):155-68
1	J:231655 Barber M, Arai Y, Morishita Y, Vigier L, Causeret F, Borello U, Ledonne F, Coppola E, Contremoulins V, Pfrieger FW, Tissir F, Govindan S, Jabaudon D, Proux-Gillardeaux V, Galli T, Pierani A, Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas. Curr Biol. 2015 Oct 5;25(19):2466-78
1*	J:173605 Beckmann J, Vitobello A, Ferralli J, Broz DK, Rijli FM, Chiquet-Ehrismann R, Human teneurin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter. BMC Dev Biol. 2011;11:35
1	J:171429 Besse L, Neti M, Anselme I, Gerhardt C, Ruther U, Laclef C, Schneider-Maunoury S, Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing. Development. 2011 May;138(10):2079-88
1	J:82130 Bishop KM, Garel S, Nakagawa Y, Rubenstein JL, O'Leary DD, Emx1 and Emx2 cooperate to regulate cortical size, lamination, neuronal differentiation, development of cortical efferents, and thalamocortical pathfinding. J Comp Neurol. 2003 Mar 17;457(4):345-60
1	J:28206 Boncinelli E, Patterns of gene expression and the subdivision of the forebrain. Hum Reprod. 1995;10(Abstract Book 2):1 (Abstr)
2	J:160580 Borello U, Cobos I, Long JE, McWhirter JR, Murre C, Rubenstein JL, FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev. 2008;3:17
1	J:174353 Boualia SK, Gaitan Y, Murawski I, Nadon R, Gupta IR, Bouchard M, Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for pax2 and emx2. PLoS One. 2011;6(6):e21529
1	J:202352 Boualia SK, Gaitan Y, Tremblay M, Sharma R, Cardin J, Kania A, Bouchard M, A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis. Dev Biol. 2013 Oct 15;382(2):555-66
2	J:98922 Bouma GJ, Albrecht KH, Washburn LL, Recknagel AK, Churchill GA, Eicher EM, Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells. Development. 2005 Jul;132(13):3045-54
7*	J:93500 Bouma GJ, Hart GT, Washburn LL, Recknagel AK, Eicher EM, Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Gene Expr Patterns. 2004 Nov;5(1):141-9
3*	J:136068 Bridgewater D, Cox B, Cain J, Lau A, Athaide V, Gill PS, Kuure S, Sainio K, Rosenblum ND, Canonical WNT/beta-catenin signaling is required for ureteric branching. Dev Biol. 2008 May 1;317(1):83-94
3*	J:155785 Brinkmeier ML, Davis SW, Carninci P, MacDonald JW, Kawai J, Ghosh D, Hayashizaki Y, Lyons RH, Camper SA, Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches. Genomics. 2009 May;93(5):449-60
1	J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18)
3	J:110605 Camus A, Perea-Gomez A, Moreau A, Collignon J, Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo. Dev Biol. 2006 Jul 15;295(2):743-55
2	J:171194 Capellini TD, Handschuh K, Quintana L, Ferretti E, Di Giacomo G, Fantini S, Vaccari G, Clarke SL, Wenger AM, Bejerano G, Sharpe J, Zappavigna V, Selleri L, Control of pelvic girdle development by genes of the Pbx family and Emx2. Dev Dyn. 2011 May;240(5):1173-89
1	J:169192 Capellini TD, Vaccari G, Ferretti E, Fantini S, He M, Pellegrini M, Quintana L, Di Giacomo G, Sharpe J, Selleri L, Zappavigna V, Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1. Development. 2010 Aug 1;137(15):2559-69
1	J:213869 Caronia-Brown G, Yoshida M, Gulden F, Assimacopoulos S, Grove EA, The cortical hem regulates the size and patterning of neocortex. Development. 2014 Jul;141(14):2855-65
3	J:114389 Cartry J, Nichane M, Ribes V, Colas A, Riou JF, Pieler T, Dolle P, Bellefroid EJ, Umbhauer M, Retinoic acid signalling is required for specification of pronephric cell fate. Dev Biol. 2006 Nov 1;299(1):35-51
1	J:199615 Cases O, Perea-Gomez A, Aguiar DP, Nykjaer A, Amsellem S, Chandellier J, Umbhauer M, Cereghini S, Madsen M, Collignon J, Verroust P, Riou JF, Creuzet SE, Kozyraki R, Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head. J Biol Chem. 2013 Jun 7;288(23):16655-70
3	J:172360 Causeret F, Ensini M, Teissier A, Kessaris N, Richardson WD, Lucas de Couville T, Pierani A, Dbx1-expressing cells are necessary for the survival of the Mammalian anterior neural and craniofacial structures. PLoS One. 2011;6(4):e19367
4	J:63713 Cecchi C, Boncinelli E, Emx homeogenes and mouse brain development. Trends Neurosci. 2000 Aug;23(8):347-52
3*	J:117873 Chang YS, Stoykova A, Chowdhury K, Gruss P, Graded expression of Zfp462 in the embryonic mouse cerebral cortex. Gene Expr Patterns. 2007 Feb;7(4):405-12
1	J:133933 Chassot AA, Ranc F, Gregoire EP, Roepers-Gajadien HL, Taketo MM, Camerino G, de Rooij DG, Schedl A, Chaboissier MC, Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. Hum Mol Genet. 2008 May 1;17(9):1264-77
2	J:103829 Chen B, Schaevitz LR, McConnell SK, Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17184-9
2	J:238877 Chen S, Yao X, Li Y, Saifudeen Z, Bachvarov D, El-Dahr SS, Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium. Development. 2015 Mar 15;142(6):1180-92
3	J:110657 Cheng X, Hsu CM, Currle DS, Hu JS, Barkovich AJ, Monuki ES, Central roles of the roof plate in telencephalic development and holoprosencephaly. J Neurosci. 2006 Jul 19;26(29):7640-9
7	J:93816 Colombo E, Galli R, Cossu G, Gecz J, Broccoli V, Mouse orthologue of ARX, a gene mutated in several X-linked forms of mental retardation and epilepsy, is a marker of adult neural stem cells and forebrain GABAergic neurons. Dev Dyn. 2004 Nov;231(3):631-9
1	J:196365 Compagnucci C, Debiais-Thibaud M, Coolen M, Fish J, Griffin JN, Bertocchini F, Minoux M, Rijli FM, Borday-Birraux V, Casane D, Mazan S, Depew MJ, Pattern and polarity in the development and evolution of the gnathostome jaw: Both conservation and heterotopy in the branchial arches of the shark, Scyliorhinus canicula. Dev Biol. 2013 May 15;377(2):428-48
1	J:40384 Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH, Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr;60(2):81-91
4	J:254118 De Clercq S, Keruzore M, Desmaris E, Pollart C, Assimacopoulos S, Preillon J, Ascenzo S, Matson CK, Lee M, Nan X, Li M, Nakagawa Y, Hochepied T, Zarkower D, Grove EA, Bellefroid EJ, DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation. Cereb Cortex. 2018 Feb 1;28(2):493-509
1	J:266242 Desmaris E, Keruzore M, Saulnier A, Ratie L, Assimacopoulos S, De Clercq S, Nan X, Roychoudhury K, Qin S, Kricha S, Chevalier C, Lingner T, Henningfeld KA, Zarkower D, Mallamaci A, Theil T, Campbell K, Pieler T, Li M, Grove EA, Bellefroid EJ, DMRT5, DMRT3, and EMX2 Cooperatively Repress Gsx2 at the Pallium-Subpallium Boundary to Maintain Cortical Identity in Dorsal Telencephalic Progenitors. J Neurosci. 2018 Oct 17;38(42):9105-9121
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:59472 Dou CL, Li S, Lai E, Dual role of brain factor-1 in regulating growth and patterning of the cerebral hemispheres. Cereb Cortex. 1999 Sep;9(6):543-50
1	J:274335 Draganova K, Zemke M, Zurkirchen L, Valenta T, Cantu C, Okoniewski M, Schmid MT, Hoffmans R, Gotz M, Basler K, Sommer L, Wnt/beta-catenin signaling regulates sequential fate decisions of murine cortical precursor cells. Stem Cells. 2015 Jan;33(1):170-82
2	J:196080 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF, The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
1*	J:83365 Esquela AF, Lee SJ, Regulation of metanephric kidney development by growth/differentiation factor 11. Dev Biol. 2003 May 15;257(2):356-70
1	J:146820 Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL, COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex. 2008 Sep;18(9):2117-31
6	J:218288 Falcone C, Filippis C, Granzotto M, Mallamaci A, Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. Glia. 2015 Mar;63(3):412-22
4	J:204883 Feenstra JM, Kanaya K, Pira CU, Hoffman SE, Eppey RJ, Oberg KC, Detection of genes regulated by Lmx1b during limb dorsalization. Dev Growth Differ. 2012 May;54(4):451-62
1*	J:48135 Fernandez AS, Pieau C, Reperant J, Boncinelli E, Wassef M, Expression of the Emx-1 and Dlx-1 homeobox genes define three molecularly distinct domains in the telencephalon of mouse, chick, turtle and frog embryos: implications for the evolution of telencephalic subdivisions in amniotes. Development. 1998 Jun;125(11):2099-111
1*	J:41809 Filosa S, RiveraPerez JA, Gomez AP, Gansmuller A, Sasaki H, Behringer RR, Ang SL, goosecoid and HNF-3 beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development. 1997 JUL;124(14):2843-2854
1	J:59428 Fode C, Ma Q, Casarosa S, Ang SL, Anderson DJ, Guillemot F, A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Genes Dev. 2000 Jan 1;14(1):67-80
2	J:170646 Fossat N, Jones V, Khoo PL, Bogani D, Hardy A, Steiner K, Mukhopadhyay M, Westphal H, Nolan PM, Arkell R, Tam PP, Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo. Development. 2011 Feb;138(4):667-76
1*	J:272552 Fregoso SP, Dwyer BE, Franco SJ, Lmx1a drives Cux2 expression in the cortical hem through activation of a conserved intronic enhancer. Development. 2019 Mar 7;146(5):dev170068
1*	J:93609 Fuccillo M, Rallu M, McMahon AP, Fishell G, Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct;131(20):5031-40
1	J:174118 Fuccillo M, Rutlin M, Fishell G, Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice. Cereb Cortex. 2006 Jul;16 Suppl 1:i96-102
1	J:204550 Fujimoto Y, Tanaka SS, Yamaguchi YL, Kobayashi H, Kuroki S, Tachibana M, Shinomura M, Kanai Y, Morohashi K, Kawakami K, Nishinakamura R, Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development. Dev Cell. 2013 Aug 26;26(4):416-30
2	J:84663 Fukuchi-Shimogori T, Grove EA, Emx2 patterns the neocortex by regulating FGF positional signaling. Nat Neurosci. 2003 Aug;6(8):825-31
1*	J:270507 Funato N, Yanagisawa H, Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans. Arch Oral Biol. 2018 Nov;95:149-155
1	J:314124 Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J, Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756
2	J:82309 Garel S, Huffman KJ, Rubenstein JL, Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants. Development. 2003 May;130(9):1903-14
2*	J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34
2	J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19
4	J:191095 Gierl MS, Gruhn WH, von Seggern A, Maltry N, Niehrs C, GADD45G functions in male sex determination by promoting p38 signaling and Sry expression. Dev Cell. 2012 Nov 13;23(5):1032-42
1	J:228726 Golonzhka O, Nord A, Tang PL, Lindtner S, Ypsilanti AR, Ferretti E, Visel A, Selleri L, Rubenstein JL, Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. Neuron. 2015 Dec 16;88(6):1192-207
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1	J:230653 Grego-Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson KV, The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. Elife. 2016;5:e12034
1	J:253278 Greig LC, Woodworth MB, Greppi C, Macklis JD, Ctip1 Controls Acquisition of Sensory Area Identity and Establishment of Sensory Input Fields in the Developing Neocortex. Neuron. 2016 Apr 20;90(2):261-77
3	J:165303 Griveau A, Borello U, Causeret F, Tissir F, Boggetto N, Karaz S, Pierani A, A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium. PLoS Biol. 2010;8(7):e1000440
1	J:104408 Grote D, Souabni A, Busslinger M, Bouchard M, Pax2/8-regulated Gata3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. Development. 2006 Jan;133(1):53-61
4*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
6*	J:33995 Gulisano M, Broccoli V, Pardini C, Boncinelli E, Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse. Eur J Neurosci. 1996 May;8(5):1037-50
1	J:119019 Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hebert JM, FGF signalling generates ventral telencephalic cells independently of SHH. Development. 2006 Aug;133(15):2937-46
1	J:58997 Hallonet M, Hollemann T, Pieler T, Gruss P, Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. Genes Dev. 1999 Dec 1;13(23):3106-14
6	J:96705 Hamasaki T, Leingartner A, Ringstedt T, O'Leary DD, EMX2 regulates sizes and positioning of the primary sensory and motor areas in neocortex by direct specification of cortical progenitors. Neuron. 2004 Aug 5;43(3):359-72
1	J:326662 Hamed AA, Kunz DJ, El-Hamamy I, Trinh QM, Subedar OD, Richards LM, Foltz W, Bullivant G, Ware M, Vladoiu MC, Zhang J, Raj AM, Pugh TJ, Taylor MD, Teichmann SA, Stein LD, Simons BD, Dirks PB, A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours. Nat Commun. 2022 Jul 19;13(1):4178
1	J:81763 Hebert JM, Lin M, Partanen J, Rossant J, McConnell SK, FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development. 2003 Mar;130(6):1101-11
2	J:53291 Hentges K, Thompson K, Peterson A, The flat-top gene is required for the expansion and regionalization of the telencephalic primordium. Development. 1999 Apr;126(8):1601-9
5	J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53
1	J:144140 Hill TP, Taketo MM, Birchmeier W, Hartmann C, Multiple roles of mesenchymal beta-catenin during murine limb patterning. Development. 2006 Apr;133(7):1219-29
2	J:300508 Hilliard SA, Li Y, Dixon A, El-Dahr SS, Mdm4 controls ureteric bud branching via regulation of p53 activity. Mech Dev. 2020 Sep;163:103616
2	J:119561 Hirata T, Nakazawa M, Muraoka O, Nakayama R, Suda Y, Hibi M, Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions. Development. 2006 Oct;133(20):3993-4004
1	J:90847 Hirota J, Mombaerts P, The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8751-5
1*	J:73652 Hitoshi S, Tropepe V, Ekker M, van der Kooy D, Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain. Development. 2002 Jan;129(1):233-44
3	J:160258 Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP, Emx2 and early hair cell development in the mouse inner ear. Dev Biol. 2010 Apr 15;340(2):547-56
1	J:125109 Huang X, Litingtung Y, Chiang C, Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly. Hum Mol Genet. 2007 Jun 15;16(12):1454-68
1*	J:157698 Ideguchi M, Palmer TD, Recht LD, Weimann JM, Murine embryonic stem cell-derived pyramidal neurons integrate into the cerebral cortex and appropriately project axons to subcortical targets. J Neurosci. 2010 Jan 20;30(3):894-904
2*	J:79394 Ishibashi M, McMahon AP, A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development. 2002 Oct;129(20):4807-19
1	J:119566 Ishimura A, Ng JK, Taira M, Young SG, Osada S, Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. Development. 2006 Oct;133(19):3919-28
2	J:127720 Jepsen K, Solum D, Zhou T, McEvilly RJ, Kim HJ, Glass CK, Hermanson O, Rosenfeld MG, SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature. 2007 Nov 15;450(7168):415-9
1	J:330450 Ji YR, Tona Y, Wafa T, Christman ME, Tourney ED, Jiang T, Ohta S, Cheng H, Fitzgerald T, Fritzsch B, Jones SM, Cullen KE, Wu DK, Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2. Nat Commun. 2022 Oct 24;13(1):6330
4	J:253478 Jiang T, Kindt K, Wu DK, Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells. Elife. 2017 Mar 7;6:e23661
1	J:65749 Jimenez D, Garcia C, de Castro F, Chedotal A, Sotelo C, de Carlos JA, Valverde F, Lopez-Mascaraque L, Evidence for intrinsic development of olfactory structures in Pax-6 mutant mice. J Comp Neurol. 2000 Dec 18;428(3):511-26
1	J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520
1	J:144066 Joshi PS, Molyneaux BJ, Feng L, Xie X, Macklis JD, Gan L, Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex. Neuron. 2008 Oct 23;60(2):258-72
5	J:238554 Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Muller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS, Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. Nat Cell Biol. 2016 Dec;18(12):1269-1280
1*	J:64339 Kanai Y, Kanai-Azuma M, Tajima Y, Birk OS, Hayashi Y, Sanai Y, Identification of a stromal cell type characterized by the secretion of a soluble integrin-binding protein, MFG-E8, in mouse early gonadogenesis. Mech Dev. 2000 Sep;96(2):223-7
1	J:127020 Katagiri R, Kurome M, Teshima Y, Ueta E, Naruse I, Prevention of ochratoxin A-induced neural tube defects by folic acid in the genetic polydactyly/arhinencephaly mouse, Pdn/Pdn. Congenit Anom (Kyoto). 2007 Sep;47(3):90-6
1	J:181719 Katoh-Fukui Y, Miyabayashi K, Komatsu T, Owaki A, Baba T, Shima Y, Kidokoro T, Kanai Y, Schedl A, Wilhelm D, Koopman P, Okuno Y, Morohashi K, Cbx2, a polycomb group gene, is required for Sry gene expression in mice. Endocrinology. 2012 Feb;153(2):913-24
2	J:257035 Kim YJ, Osborn DP, Lee JY, Araki M, Araki K, Mohun T, Kansakoski J, Brandstack N, Kim HT, Miralles F, Kim CH, Brown NA, Kim HG, Martinez-Barbera JP, Ataliotis P, Raivio T, Layman LC, Kim SH, WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome. EMBO Rep. 2018 Feb;19(2):269-289
3	J:98539 Kimura J, Suda Y, Kurokawa D, Hossain ZM, Nakamura M, Takahashi M, Hara A, Aizawa S, Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. J Neurosci. 2005 May 25;25(21):5097-108
1	J:244839 Kimura-Yoshida C, Mochida K, Ellwanger K, Niehrs C, Matsuo I, Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure. EBioMedicine. 2015 Jun;2(6):513-27
1	J:306060 Kindt KS, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, Tarchini B, EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861
1	J:178935 Kitagaki J, Ueda Y, Chi X, Sharma N, Elder CM, Truffer E, Costantini F, Lewandoski M, Perantoni AO, FGF8 is essential for formation of the ductal system in the male reproductive tract. Development. 2011 Dec;138(24):5369-78
1	J:117793 Kudo LC, Karsten SL, Chen J, Levitt P, Geschwind DH, Genetic analysis of anterior-posterior expression gradients in the developing mammalian forebrain. Cereb Cortex. 2007 Sep;17(9):2108-22
1	J:101708 Kuijper S, Beverdam A, Kroon C, Brouwer A, Candille S, Barsh G, Meijlink F, Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes. Development. 2005 Apr;132(7):1601-10
1*	J:91011 Kurokawa D, Kiyonari H, Nakayama R, Kimura-Yoshida C, Matsuo I, Aizawa S, Regulation of Otx2 expression and its functions in mouse forebrain and midbrain. Development. 2004 Jul;131(14):3319-31
1*	J:91012 Kurokawa D, Takasaki N, Kiyonari H, Nakayama R, Kimura-Yoshida C, Matsuo I, Aizawa S, Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development. 2004 Jul;131(14):3307-17
4	J:168643 Kusaka M, Katoh-Fukui Y, Ogawa H, Miyabayashi K, Baba T, Shima Y, Sugiyama N, Sugimoto Y, Okuno Y, Kodama R, Iizuka-Kogo A, Senda T, Sasaoka T, Kitamura K, Aizawa S, Morohashi K, Abnormal epithelial cell polarity and ectopic epidermal growth factor receptor (EGFR) expression induced in Emx2 KO embryonic gonads. Endocrinology. 2010 Dec;151(12):5893-904
1	J:84901 Kuschel S, Ruther U, Theil T, A disrupted balance between Bmp/Wnt and Fgf signaling underlies the ventralization of the Gli3 mutant telencephalon. Dev Biol. 2003 Aug 15;260(2):484-95
1	J:81797 Lagutin OV, Zhu CC, Kobayashi D, Topczewski J, Shimamura K, Puelles L, Russell HR, McKinnon PJ, Solnica-Krezel L, Oliver G, Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development. Genes Dev. 2003 Feb 1;17(3):368-79
1	J:173657 Lavery R, Lardenois A, Ranc-Jianmotamedi F, Pauper E, Gregoire EP, Vigier C, Moreilhon C, Primig M, Chaboissier MC, XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes. Dev Biol. 2011 Jun 1;354(1):111-22
1	J:143844 Leingartner A, Thuret S, Kroll TT, Chou SJ, Leasure JL, Gage FH, O'Leary DD, Cortical area size dictates performance at modality-specific behaviors. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4153-8
1*	J:82457 Ligon KL, Echelard Y, Assimacopoulos S, Danielian PS, Kaing S, Grove EA, McMahon AP, Rowitch DH, Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development. 2003 May;130(10):2275-87
1	J:122519 Linton JM, Martin GR, Reichardt LF, The ECM protein nephronectin promotes kidney development via integrin {alpha}8{beta}1-mediated stimulation of Gdnf expression. Development. 2007 Jul;134(13):2501-9
1*	J:180785 Loebel DA, Hor AC, Bildsoe H, Jones V, Chen YT, Behringer RR, Tam PP, Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Dev Biol. 2012 Feb 15;362(2):132-40
1	J:157251 Lokmane L, Heliot C, Garcia-Villalba P, Fabre M, Cereghini S, vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis. Development. 2010 Jan;137(2):347-57
1*	J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1*	J:173287 Long JE, Swan C, Liang WS, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
2*	J:78716 Lopez-Bendito G, Chan CH, Mallamaci A, Parnavelas J, Molnar Z, Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus. J Comp Neurol. 2002 Sep 16;451(2):153-69
2*	J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:165487 Magnani D, Hasenpusch-Theil K, Jacobs EC, Campagnoni AT, Price DJ, Theil T, The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence. J Neurosci. 2010 Oct 13;30(41):13883-94
1*	J:83430 Majumdar A, Vainio S, Kispert A, McMahon J, McMahon AP, Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development. 2003 Jul;130(14):3175-85
11*	J:51432 Mallamaci A, Iannone R, Briata P, Pintonello L, Mercurio S, Boncinelli E, Corte G, EMX2 protein in the developing mouse brain and olfactory area. Mech Dev. 1998 Oct;77(2):165-72
1	J:119936 Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ, Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization. Development. 2007 Feb;134(3):545-55
1	J:171704 Manuel MN, Martynoga B, Molinek MD, Quinn JC, Kroemmer C, Mason JO, Price DJ, The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels. Neural Dev. 2011;6:9
1	J:123406 Miquelajauregui A, Van de Putte T, Polyakov A, Nityanandam A, Boppana S, Seuntjens E, Karabinos A, Higashi Y, Huylebroeck D, Tarabykin V, Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12919-24
7*	J:40605 Miyamoto N, Yoshida M, Kuratani S, Matsuo I, Aizawa S, Defects of urogenital development in mice lacking Emx2. Development. 1997 May;124(9):1653-64
2*	J:135688 Moisan V, Bomgardner D, Tremblay JJ, Expression of the Ladybird-like homeobox 2 transcription factor in the developing mouse testis and epididymis. BMC Dev Biol. 2008;8:22
4	J:349889 Moreno JA, Dudchenko O, Feigin CY, Mereby SA, Chen Z, Ramos R, Almet AA, Sen H, Brack BJ, Johnson MR, Li S, Wang W, Gaska JM, Ploss A, Weisz D, Omer AD, Yao W, Colaric Z, Kaur P, Leger JS, Nie Q, Mena A, Flanagan JP, Keller G, Sanger T, Ostrow B, Plikus MV, Kvon EZ, Aiden EL, Mallarino R, Emx2 underlies the development and evolution of marsupial gliding membranes. Nature. 2024 May;629(8010):127-135
2	J:331901 Muthu V, Rohacek AM, Yao Y, Rakowiecki SM, Brown AS, Zhao YT, Meyers J, Won KJ, Ramdas S, Brown CD, Peterson KA, Epstein DJ, Genomic architecture of Shh-dependent cochlear morphogenesis. Development. 2019 Sep 19;146(18)
1	J:174499 Muzio L, DiBenedetto B, Stoykova A, Boncinelli E, Gruss P, Mallamaci A, Emx2 and Pax6 control regionalization of the pre-neuronogenic cortical primordium. Cereb Cortex. 2002 Feb;12(2):129-39
1	J:98698 Muzio L, Mallamaci A, Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. J Neurosci. 2005 Apr 27;25(17):4435-41
1*	J:263835 Newman EA, Kim DW, Wan J, Wang J, Qian J, Blackshaw S, Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Dev Biol. 2018 Jul 15;439(2):102-111
1	J:266266 Newman EA, Wu D, Taketo MM, Zhang J, Blackshaw S, Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus. Dev Biol. 2018 Oct 15;442(2):236-248
2*	J:171473 Nie X, Xu J, El-Hashash A, Xu PX, Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis. Dev Biol. 2011 Apr 1;352(1):141-51
1	J:288722 Nilsson D, Heglind M, Arani Z, Enerback S, Foxc2 is essential for podocyte function. Physiol Rep. 2019 May;7(9):e14083
1	J:176531 Nowakowski TJ, Mysiak KS, Pratt T, Price DJ, Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon. PLoS One. 2011;6(8):e23013
1*	J:174498 Oldekamp J, Kraemer N, Alvarez-Bolado G, Skutella T, bHLH gene expression in the Emx2-deficient dentate gyrus reveals defective granule cells and absence of migrating precursors. Cereb Cortex. 2004 Sep;14(9):1045-58
1	J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55
4	J:179736 Paek H, Antoine MW, Diaz F, Hebert JM, Increased beta-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics. Dev Dyn. 2012 Feb;241(2):242-6
1*	J:69851 Patterson LT, Pembaur M, Potter SS, Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney. Development. 2001 Jun;128(11):2153-61
1*	J:104938 Pedersen A, Skjong C, Shawlot W, Lim 1 is required for nephric duct extension and ureteric bud morphogenesis. Dev Biol. 2005 Dec 15;288(2):571-81
2*	J:37631 Pellegrini M, Mansouri A, Simeone A, Boncinelli E, Gruss P, Dentate gyrus formation requires Emx2. Development. 1996 Dec;122(12):3893-8
7*	J:68674 Pellegrini M, Pantano S, Fumi MP, Lucchini F, Forabosco A, Agenesis of the scapula in Emx2 homozygous mutants. Dev Biol. 2001 Apr 1;232(1):149-56
10*	J:45222 Pellegrini M, Pantano S, Lucchini F, Fumi M, Forabosco A, Emx2 developmental expression in the primordia of the reproductive and excretory systems. Anat Embryol (Berl). 1997 Dec;196(6):427-33
1*	J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182
3	J:127039 Rash BG, Grove EA, Patterning the dorsal telencephalon: a role for sonic hedgehog?. J Neurosci. 2007 Oct 24;27(43):11595-603
1	J:178496 Rash BG, Grove EA, Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain. Dev Biol. 2011 Nov 15;359(2):242-50
1*	J:76367 Rathjen J, Haines BP, Hudson KM, Nesci A, Dunn S, Rathjen PD, Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population. Development. 2002 Jun;129(11):2649-61
1	J:168845 Reginensi A, Clarkson M, Neirijnck Y, Lu B, Ohyama T, Groves AK, Sock E, Wegner M, Costantini F, Chaboissier MC, Schedl A, SOX9 controls epithelial branching by activating RET effector genes during kidney development. Hum Mol Genet. 2011 Mar 15;20(6):1143-53
5	J:89093 Rhodes CR, Parkinson N, Tsai H, Brooker D, Mansell S, Spurr N, Hunter AJ, Steel KP, Brown SD, The homeobox gene Emx2 underlies middle ear and inner ear defects in the deaf mouse mutant pardon. J Neurocytol. 2003 Nov;32(9):1143-54
3	J:104523 Ribes V, Wang Z, Dolle P, Niederreither K, Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling. Development. 2006 Jan;133(2):351-61
1	J:220958 Rosenthal EH, Tonchev AB, Stoykova A, Chowdhury K, Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012 Nov;22(11):2144-56
1	J:196967 Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Houart C, Meyer G, Blackshaw S, Tole S, LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis. J Neurosci. 2013 Apr 17;33(16):6877-84
1	J:336383 Ruiz-Reig N, Andres B, Huilgol D, Grove EA, Tissir F, Tole S, Theil T, Herrera E, Fairen A, Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells. Cereb Cortex. 2017 May 1;27(5):2841-2856
3	J:166617 Sakurai Y, Kurokawa D, Kiyonari H, Kajikawa E, Suda Y, Aizawa S, Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization. Dev Biol. 2010 Nov 15;347(2):392-403
3*	J:215514 Saulnier A, Keruzore M, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Gotz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ, The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
1	J:124257 Schmidt-Ott KM, Masckauchan TN, Chen X, Hirsh BJ, Sarkar A, Yang J, Paragas N, Wallace VA, Dufort D, Pavlidis P, Jagla B, Kitajewski J, Barasch J, {beta}-catenin/TCF/Lef controls a differentiation-associated transcriptional program in renal epithelial progenitors. Development. 2007 Sep;134(17):3177-90
2*	J:93057 Schuurmans C, Armant O, Nieto M, Stenman JM, Britz O, Klenin N, Brown C, Langevin LM, Seibt J, Tang H, Cunningham JM, Dyck R, Walsh C, Campbell K, Polleux F, Guillemot F, Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21;23(14):2892-902
3*	J:31212 Shimamura K, Hartigan DJ, Martinez S, Puelles L, Rubenstein JL, Longitudinal organization of the anterior neural plate and neural tube. Development. 1995 Dec;121(12):3923-33
2	J:39255 Shimamura K, Martinez S, Puelles L, Rubenstein JL, Patterns of gene expression in the neural plate and neural tube subdivide the embryonic forebrain into transverse and longitudinal domains. Dev Neurosci. 1997;19(1):88-96
4*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
2*	J:77124 Shinozaki K, Miyagi T, Yoshida M, Miyata T, Ogawa M, Aizawa S, Suda Y, Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development. 2002 Jul;129(14):3479-92
1	J:133339 Silvestri C, Narimatsu M, von Both I, Liu Y, Tan NB, Izzi L, McCaffery P, Wrana JL, Attisano L, Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development. Dev Cell. 2008 Mar;14(3):411-23
2*	J:2076 Simeone A, Acampora D, Gulisano M, Stornaiuolo A, Boncinelli E, Nested expression domains of four homeobox genes in developing rostral brain [see comments]. Nature. 1992 Aug 20;358(6388):687-90
1*	J:19476 Simeone A, D'Apice MR, Nigro V, Casanova J, Graziani F, Acampora D, Avantaggiato V, Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila. Neuron. 1994 Jul;13(1):83-101
10*	J:1461 Simeone A, Gulisano M, Acampora D, Stornaiuolo A, Rambaldi M, Boncinelli E, Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 1992 Jul;11(7):2541-50
1	J:86868 Simon R, Lufkin T, Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation. Mol Cell Biol. 2003 Dec;23(24):9046-60
1	J:96006 Steele-Perkins G, Plachez C, Butz KG, Yang G, Bachurski CJ, Kinsman SL, Litwack ED, Richards LJ, Gronostajski RM, The transcription factor gene Nfib is essential for both lung maturation and brain development. Mol Cell Biol. 2005 Jan;25(2):685-98
3	J:108506 Storm EE, Garel S, Borello U, Hebert JM, Martinez S, McConnell SK, Martin GR, Rubenstein JL, Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers. Development. 2006 May;133(9):1831-44
1*	J:36832 Stoykova A, Fritsch R, Walther C, Gruss P, Forebrain patterning defects in Small eye mutant mice. Development. 1996 Nov;122(11):3453-65
1	J:102077 Stoykova A, Hatano O, Gruss P, Gotz M, Increase in reelin-positive cells in the marginal zone of Pax6 mutant mouse cortex. Cereb Cortex. 2003 Jun;13(6):560-71
4*	J:70745 Suda Y, Hossain ZM, Kobayashi C, Hatano O, Yoshida M, Matsuo I, Aizawa S, Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
9*	J:163926 Suda Y, Kokura K, Kimura J, Kajikawa E, Inoue F, Aizawa S, The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone. Development. 2010 Sep 1;137(17):2939-49
1*	J:45681 Suda Y, Matsuo I, Aizawa S, Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain. Mech Dev. 1997 Dec;69(1-2):125-41
1*	J:51989 Suda Y, Nakabayashi J, Matsuo I, Aizawa S, Functional equivalency between Otx2 and Otx1 in development of the rostral head. Development. 1999 Feb;126(4):743-57
1*	J:233062 Sun J, Rockowitz S, Xie Q, Ashery-Padan R, Zheng D, Cvekl A, Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development. Nucleic Acids Res. 2015 Aug 18;43(14):6827-46
2	J:149516 Szabo NE, Zhao T, Cankaya M, Theil T, Zhou X, Alvarez-Bolado G, Role of neuroepithelial Sonic hedgehog in hypothalamic patterning. J Neurosci. 2009 May 27;29(21):6989-7002
4	J:253989 Taguchi A, Nishinakamura R, Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell. 2017 Dec 7;21(6):730-746.e6
2*	J:194960 Tai G, Hohenstein P, Davies JA, FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique. Biol Open. 2013;2:416-423
1	J:183402 Taniguchi K, Anderson AE, Sutherland AE, Wotton D, Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway. PLoS Genet. 2012 Feb;8(2):e1002524
2	J:104845 Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ, Radial glia cells are candidate stem cells of ependymoma. Cancer Cell. 2005 Oct;8(4):323-35
3	J:277380 Telley L, Agirman G, Prados J, Amberg N, Fievre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D, Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 2019 May 10;364(6440)
4*	J:53903 Theil T, Alvarez-Bolado G, Walter A, Ruther U, Gli3 is required for Emx gene expression during dorsal telencephalon development. Development. 1999 Aug;126(16):3561-71
1*	J:79849 Theil T, Aydin S, Koch S, Grotewold L, Ruther U, Wnt and Bmp signalling cooperatively regulate graded Emx2 expression in the dorsal telencephalon. Development. 2002 Jul;129(13):3045-54
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:160732 Thomson RE, Kind PC, Graham NA, Etherson ML, Kennedy J, Fernandes AC, Marques CS, Hevner RF, Iwata T, Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex. Neural Dev. 2009;4:4
2*	J:74631 Tian E, Kimura C, Takeda N, Aizawa S, Matsuo I, Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
8	J:234706 Tian-Zhong M, Bi C, Ying Z, Xia J, Cai-Ling P, Yun-Shan Z, Mei-Wen H, Yan-Ru N, Critical role of Emx2 in the pluripotency - differentiation transition in male gonocytes via regulation of FGF9/NODAL pathway. Reproduction. 2016 Jun;151(6):673-81
1*	J:72659 Tole S, Goudreau G, Assimacopoulos S, Grove EA, Emx2 is required for growth of the hippocampus but not for hippocampal field specification. J Neurosci. 2000 Apr 1;20(7):2618-25
1*	J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51
1*	J:59923 Tole S, Ragsdale CW, Grove EA, Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J). Dev Biol. 2000 Jan 15;217(2):254-65
3	J:98620 Tole S, Remedios R, Saha B, Stoykova A, Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex. J Neurosci. 2005 Mar 9;25(10):2753-60
1	J:198684 Trowe MO, Zhao L, Weiss AC, Christoffels V, Epstein DJ, Kispert A, Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis. Development. 2013 Jun;140(11):2299-309
4*	J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26
1	J:119939 Uehara M, Yashiro K, Mamiya S, Nishino J, Chambon P, Dolle P, Sakai Y, CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse. Dev Biol. 2007 Feb 15;302(2):399-411
2*	J:137652 Ueta E, Kurome M, Teshima Y, Kodama M, Otsuka Y, Naruse I, Altered signaling pathway in the dysmorphogenesis of telencephalon in the Gli3 depressed mouse embryo, Pdn/Pdn. Congenit Anom (Kyoto). 2008 Jun;48(2):74-80
1	J:270530 Van Otterloo E, Li H, Jones KL, Williams T, AP-2alpha and AP-2beta cooperatively orchestrate homeobox gene expression during branchial arch patterning. Development. 2018 Jan 25;145(2):dev157438
1	J:235702 Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, Liu W, Bai Y, Yang Y, Wang H, Gao S, Wang X, LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 2016;7:10481
1	J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1	J:142500 Willaredt MA, Hasenpusch-Theil K, Gardner HA, Kitanovic I, Hirschfeld-Warneken VC, Gojak CP, Gorgas K, Bradford CL, Spatz J, Wolfl S, Theil T, Tucker KL, A crucial role for primary cilia in cortical morphogenesis. J Neurosci. 2008 Nov 26;28(48):12887-900
1	J:241749 Wilson SL, Wilson JP, Wang C, Wang B, McConnell SK, Primary cilia and Gli3 activity regulate cerebral cortical size. Dev Neurobiol. 2012 Sep;72(9):1196-212
2	J:40102 Wlodarczyk BC, Craig JC, Bennett GD, Calvin JA, Finnell RH, Valproic acid-induced changes in gene expression during neurulation in a mouse model. Teratology. 1996 Dec;54(6):284-97
1	J:152813 Wolf M, Lommes P, Sock E, Reiprich S, Friedrich RP, Kriesch J, Stolt CC, Bermingham JR Jr, Wegner M, Replacement of related POU transcription factors leads to severe defects in mouse forebrain development. Dev Biol. 2009 Aug 15;332(2):418-28
1	J:313451 Xu L, Zheng Y, Li X, Wang A, Huo D, Li Q, Wang S, Luo Z, Liu Y, Xu F, Wu X, Wu M, Zhou Y, Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice. Sci Adv. 2021 Jan;7(1)
2*	J:26720 Xuan S, Baptista CA, Balas G, Tao W, Soares VC, Lai E, Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron. 1995 Jun;14(6):1141-52
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
5*	J:38397 Yoshida M, Suda Y, Matsuo I, Miyamoto N, Takeda N, Kuratani S, Aizawa S, Emx1 and Emx2 functions in development of dorsal telencephalon. Development. 1997 Jan;124(1):101-11
1	J:319920 Ypsilanti AR, Pattabiraman K, Catta-Preta R, Golonzhka O, Lindtner S, Tang K, Jones IR, Abnousi A, Juric I, Hu M, Shen Y, Dickel DE, Visel A, Pennachio LA, Hawrylycz M, Thompson CL, Zeng H, Barozzi I, Nord AS, Rubenstein JL, Transcriptional network orchestrating regional patterning of cortical progenitors. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2024795118
2	J:184004 Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, Machanick P, Gray PA, van Oudenaarden A, Rowitch DH, Stiles CD, Ma Q, Grimmond SM, Bailey TL, Little MH, McMahon AP, Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development. 2012 May;139(10):1863-73
2*	J:62026 Zappone MV, Galli R, Catena R, Meani N, De Biasi S, Mattei E, Tiveron C, Vescovi AL, Lovell-Badge R, Ottolenghi S, Nicolis SK, Sox2 regulatory sequences direct expression of a (beta)-geo transgene to telencephalic neural stem cells and precursors of the mouse embryo, revealing regionalization of gene expression in CNS stem cells. Development. 2000 Jun;127(11):2367-82
3	J:160653 Zembrzycki A, Griesel G, Stoykova A, Mansouri A, Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain. Neural Dev. 2007;2:8
1	J:223313 Zembrzycki A, Perez-Garcia CG, Wang CF, Chou SJ, O'Leary DD, Postmitotic regulation of sensory area patterning in the mammalian neocortex by Lhx2. Proc Natl Acad Sci U S A. 2015 May 26;112(21):6736-41
1	J:256576 Zembrzycki A, Stocker AM, Leingartner A, Sahara S, Chou SJ, Kalatsky V, May SR, Stryker MP, O'Leary DD, Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas. Elife. 2015 Dec 24;4:e11416
2	J:261961 Zhang H, Zhang L, Sun T, Cohesive Regulation of Neural Progenitor Development by microRNA miR-26, Its Host Gene Ctdsp and Target Gene Emx2 in the Mouse Embryonic Cerebral Cortex. Front Mol Neurosci. 2018;11:44
1	J:111598 Zhao T, Kraemer N, Oldekamp J, Cankaya M, Szabo N, Conrad S, Skutella T, Alvarez-Bolado G, Emx2 in the developing hippocampal fissure region. Eur J Neurosci. 2006 Jun;23(11):2895-907
2	J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714
1	J:55103 Zhao Y, Sheng HZ, Amini R, Grinberg A, Lee E, Huang S, Taira M, Westphal H, Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Science. 1999 May 14;284(5417):1155-8
1	J:344238 Zheng Y, Zhao C, Song Q, Xu L, Zhang B, Hu G, Kong X, Li S, Li X, Shen Y, Zhuang L, Wu M, Liu Y, Zhou Y, Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities. Cell Rep. 2023 Dec 26;42(12):113496
1	J:62712 Zhong W, Jiang MM, Schonemann MD, Meneses JJ, Pedersen RA, Jan LY, Jan YN, Mouse numb is an essential gene involved in cortical neurogenesis. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6844-9
1	J:71195 Zhou C, Tsai SY, Tsai MJ, COUP-TFI: an intrinsic factor for early regionalization of the neocortex. Genes Dev. 2001 Aug 15;15(16):2054-9
2*	J:41878 Zoltewicz JS, Plummer NW, Lin MI, Peterson AS, oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1. Development. 1999 Nov;126(22):5085-95
1	J:87046 Zoltewicz JS, Stewart NJ, Leung R, Peterson AS, Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development. 2004 Jan;131(1):3-14