Symbol Name ID |
Ptk2
PTK2 protein tyrosine kinase 2 MGI:95481 |
Age | E6 | E6.5 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E20 | E | P |
Immunohistochemistry (section) | 1 | 5 | 1 | 1 | 1 | 2 | 5 | 6 | 1 | 2 | 4 | 2 | 1 | 15 | ||||||||||||||
In situ RNA (section) | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 4 | ||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | ||||||||||||||||||||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||||||||||||||||
Western blot | 1 | 2 | 5 | 1 | 4 | 3 | 1 | 9 | 1 | 6 | 6 | 4 | 1 | 3 | 1 | 5 | 1 | 1 | 26 | |||||||||
RT-PCR | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 4 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 6 | ||||||||||
cDNA clones | 1 | 1 | 1 | 1 |
Ptk2 PTK2 protein tyrosine kinase 2 (Synonyms: Fadk, FAK, FRNK) | |
Results | Reference |
1* | J:176660 Abler LL, Keil KP, Mehta V, Joshi PS, Schmitz CT, Vezina CM, A high-resolution molecular atlas of the fetal mouse lower urogenital tract. Dev Dyn. 2011 Oct;240(10):2364-77 |
3* | J:211339 Al-Zahrani KN, Sekhon P, Tessier DR, Yockell-Lelievre J, Pryce BR, Baron KD, Howe GA, Sriram RK, Daniel K, Mckay M, Lo V, Quizi J, Addison CL, Gruslin A, Sabourin LA, Essential role for the SLK protein kinase in embryogenesis and placental tissue development. Dev Dyn. 2014 May;243(5):640-51 |
2 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
1 | J:85994 Aszodi A, Hunziker EB, Brakebusch C, Fassler R, Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis. Genes Dev. 2003 Oct 1;17(19):2465-79 |
1 | J:164943 Bae GU, Yang YJ, Jiang G, Hong M, Lee HJ, Tessier-Lavigne M, Kang JS, Krauss RS, Neogenin regulates skeletal myofiber size and focal adhesion kinase and extracellular signal-regulated kinase activities in vivo and in vitro. Mol Biol Cell. 2009 Dec;20(23):4920-31 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
13* | J:164222 Beverdam A, Svingen T, Bagheri-Fam S, McClive P, Sinclair AH, Harley VR, Koopman P, Protein tyrosine kinase 2 beta (PTK2B), but not focal adhesion kinase (FAK), is expressed in a sexually dimorphic pattern in developing mouse gonads. Dev Dyn. 2010 Oct;239(10):2735-41 |
4* | J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247 |
1 | J:109819 Bock HH, Herz J, Reelin activates SRC family tyrosine kinases in neurons. Curr Biol. 2003 Jan 8;13(1):18-26 |
2 | J:104401 Braren R, Hu H, Kim YH, Beggs HE, Reichardt LF, Wang R, Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. J Cell Biol. 2006 Jan 2;172(1):151-62 |
2 | J:311855 Brudvig JJ, Cain JT, Schmidt-Grimminger GG, Stumpo DJ, Roux KJ, Blackshear PJ, Weimer JM, MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation. Mol Neurobiol. 2018 Nov;55(11):8388-8402 |
3* | J:316187 Chacon MR, Navarro AI, Cuesto G, del Pino I, Scott R, Morales M, Rico B, Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth. Development. 2012 Sep;139(17):3200-10 |
1* | J:279273 Chen G, Yao Y, Xu G, Zhang X, Regional difference in microRNA regulation in the skull vault. Dev Dyn. 2019 Oct;248(10):1009-1019 |
2 | J:191848 Cheng Z, Sundberg-Smith LJ, Mangiante LE, Sayers RL, Hakim ZS, Musunuri S, Maguire CT, Majesky MW, Zhou Z, Mack CP, Taylor JM, Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature. Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2193-202 |
3 | J:175562 Cho IH, Lee KW, Ha HY, Han PL, JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains. Exp Mol Med. 2011 Aug 31;43(8):462-70 |
3 | J:12761 Choi K, Kennedy M, Keller G, Expression of a gene encoding a unique protein-tyrosine kinase within specific fetal- and adult-derived hematopoietic lineages. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5747-51 |
2* | J:157804 Corsi JM, Houbron C, Billuart P, Brunet I, Bouvree K, Eichmann A, Girault JA, Enslen H, Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development. J Biol Chem. 2009 Dec 11;284(50):34769-76 |
4* | J:113411 Corsi JM, Rouer E, Girault JA, Enslen H, Organization and post-transcriptional processing of focal adhesion kinase gene. BMC Genomics. 2006;7:198 |
1* | J:190037 Debrand E, Conti FJ, Bate N, Spence L, Mazzeo D, Pritchard CA, Monkley SJ, Critchley DR, Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile. Biochem Biophys Res Commun. 2012 Sep 21;426(2):190-5 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
7 | J:164768 DiMichele LA, Hakim ZS, Sayers RL, Rojas M, Schwartz RJ, Mack CP, Taylor JM, Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth. Circ Res. 2009 May 22;104(10):1201-8 |
5* | J:164221 Enciso JM, Konecny CM, Karpen HE, Hirschi KK, Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo. Dev Dyn. 2010 Oct;239(10):2570-83 |
3* | J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998; |
6* | J:29978 Furuta Y, Ilic D, Kanazawa S, Takeda N, Yamamoto T, Aizawa S, Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK. Oncogene. 1995 Nov 16;11(10):1989-95 |
1 | J:335821 Gao G, Li X, Jiang Z, Osorio L, Tang YL, Yu X, Jin G, Zhou Z, Isthmin-1 (Ism1) modulates renal branching morphogenesis and mesenchyme condensation during early kidney development. Nat Commun. 2023 Apr 25;14(1):2378 |
3* | J:119278 Gill SE, Pape MC, Leco KJ, Tissue inhibitor of metalloproteinases 3 regulates extracellular matrix--cell signaling during bronchiole branching morphogenesis. Dev Biol. 2006 Oct 15;298(2):540-54 |
1* | J:228638 Greenman R, Gorelik A, Sapir T, Baumgart J, Zamor V, Segal-Salto M, Levin-Zaidman S, Aidinis V, Aoki J, Nitsch R, Vogt J, Reiner O, Non-cell autonomous and non-catalytic activities of ATX in the developing brain. Front Neurosci. 2015;9:53 |
1 | J:119506 Grove M, Komiyama NH, Nave KA, Grant SG, Sherman DL, Brophy PJ, FAK is required for axonal sorting by Schwann cells. J Cell Biol. 2007 Jan 29;176(3):277-82 |
3* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
2 | J:95744 Ha HY, Cho IH, Lee KW, Lee KW, Song JY, Kim KS, Yu YM, Lee JK, Song JS, Yang SD, Shin HS, Han PL, The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1. Dev Biol. 2005 Jan 1;277(1):184-99 |
2 | J:123620 Hakim ZS, DiMichele LA, Doherty JT, Homeister JW, Beggs HE, Reichardt LF, Schwartz RJ, Brackhan J, Smithies O, Mack CP, Taylor JM, Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Mol Cell Biol. 2007 Aug;27(15):5352-64 |
11* | J:12194 Hanks SK, Calalb MB, Harper MC, Patel SK, Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8487-91 |
1 | J:220518 Hu H, Matter ML, Issa-Jahns L, Jijiwa M, Kraemer N, Musante L, de la Vega M, Ninnemann O, Schindler D, Damatova N, Eirich K, Sifringer M, Schrotter S, Eickholt BJ, van den Heuvel L, Casamina C, Stoltenburg-Didinger G, Ropers HH, Wienker TF, Hubner C, Kaindl AM, Mutations in PTRH2 cause novel infantile-onset multisystem disease with intellectual disability, microcephaly, progressive ataxia, and muscle weakness. Ann Clin Transl Neurol. 2014 Dec;1(12):1024-35 |
1 | J:100466 Huangfu D, Anderson KV, Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11325-30 |
1 | J:184432 Ichikawa-Tomikawa N, Ogawa J, Douet V, Xu Z, Kamikubo Y, Sakurai T, Kohsaka S, Chiba H, Hattori N, Yamada Y, Arikawa-Hirasawa E, Laminin alpha1 is essential for mouse cerebellar development. Matrix Biol. 2012 Jan;31(1):17-28 |
1* | J:29273 Ilic D, Furuta Y, Kanazawa S, Takeda N, Sobue K, Nakatsuji N, Nomura S, Fujimoto J, Okada M, Yamamoto T, Aizawa S, Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature. 1995 Oct 12;377(6549):539-44 |
2 | J:130822 Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH Jr, Kalluri R, Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev Biol. 2008 Jan 15;313(2):584-93 |
8 | J:121630 Kokkinos MI, Brown HJ, de Iongh RU, Focal adhesion kinase (FAK) expression and activation during lens development. Mol Vis. 2007;13:418-30 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
5* | J:316578 Lade A, Ranganathan S, Luo J, Monga SP, Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98 |
1* | J:316617 Li W, Chen L, Chen Z, Wu L, Feng J, Wang F, Shoff L, Li X, Donly KJ, MacDougall M, Chen S, Dentin sialoprotein facilitates dental mesenchymal cell differentiation and dentin formation. Sci Rep. 2017 Mar 22;7(1):300 |
1* | J:180459 Lim ST, Chen XL, Lim Y, Hanson DA, Vo TT, Howerton K, Larocque N, Fisher SJ, Schlaepfer DD, Ilic D, Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. Mol Cell. 2008 Jan 18;29(1):9-22 |
1 | J:165360 Lim ST, Chen XL, Tomar A, Miller NL, Yoo J, Schlaepfer DD, Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation. J Biol Chem. 2010 Jul 9;285(28):21526-36 |
3 | J:185347 Lim ST, Miller NL, Chen XL, Tancioni I, Walsh CT, Lawson C, Uryu S, Weis SM, Cheresh DA, Schlaepfer DD, Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression. J Cell Biol. 2012 Jun 25;197(7):907-19 |
1 | J:293699 Lin JI, Feinstein TN, Jha A, McCleary JT, Xu J, Arrigo AB, Rong G, Maclay LM, Ridge T, Xu X, Lo CW, Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening. Commun Biol. 2020 Jun 16;3(1):312 |
2 | J:353576 Lin Y, Yang Q, Lin X, Liu X, Qian Y, Xu D, Cao N, Han X, Zhu Y, Hu W, He X, Yu Z, Kong X, Zhu L, Zhong Z, Liu K, Zhou B, Wang Y, Peng J, Zhu W, Wang J, Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation. Circulation. 2024 Feb 20;149(8):605-626 |
2* | J:61486 Littlewood Evans A, Muller U, Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Nat Genet. 2000 Apr;24(4):424-8 |
2 | J:279065 Liu W, Han F, Qu S, Yao Y, Zhao J, Akhtar ML, Ci Y, Zhang H, Li H, Zhao Y, Yue L, Zhang Y, Wang C, Li Y, MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development. Cell Death Dis. 2018 Sep 24;9(10):999 |
1 | J:306850 Lu T, Lin X, Pan YH, Yang N, Ye S, Zhang Q, Wang C, Zhu R, Zhang T, Wisniewski TM, Cao Z, Ding BS, Dang S, Zhang W, ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation. iScience. 2020 Aug 20;23(9):101472 |
1 | J:326537 Mahmoud M, Evans I, Wisniewski L, Tam Y, Walsh C, Walker-Samuel S, Frankel P, Scambler P, Zachary I, Bcar1/p130Cas is essential for ventricular development and neural crest cell remodelling of the cardiac outflow tract. Cardiovasc Res. 2022 Jun 29;118(8):1993-2005 |
1 | J:354234 Makhlouf A, Wang A, Sato N, Rosa VS, Shahbazi MN, Integrin signaling in pluripotent cells acts as a gatekeeper of mouse germline entry. Sci Adv. 2024 Sep 6;10(36):eadk2252 |
1 | J:221026 Miller NL, Lawson C, Chen XL, Lim ST, Schlaepfer DD, Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins. PLoS One. 2012;7(5):e37830 |
1 | J:232801 Misra A, Sheikh AQ, Kumar A, Luo J, Zhang J, Hinton RB, Smoot L, Kaplan P, Urban Z, Qyang Y, Tellides G, Greif DM, Integrin beta3 inhibition is a therapeutic strategy for supravalvular aortic stenosis. J Exp Med. 2016 Mar 7;213(3):451-63 |
1 | J:269440 Morgan-Smith M, Wu Y, Zhu X, Pringle J, Snider WD, GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation. Elife. 2014 Jul 29;3:e02663 |
1 | J:203460 Nakaya T, Ishiguro KI, Belzil C, Rietsch AM, Yu Q, Mizuno SI, Bronson RT, Geng Y, Nguyen MD, Akashi K, Sicinski P, Nakatani Y, p600 Plays Essential Roles in Fetal Development. PLoS One. 2013;8(6):e66269 |
1 | J:317064 O'Neill TJ 4th, Mack CP, Taylor JM, Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest. J Mol Cell Cardiol. 2012 Aug;53(2):156-64 |
2 | J:105371 Peng X, Kraus MS, Wei H, Shen TL, Pariaut R, Alcaraz A, Ji G, Cheng L, Yang Q, Kotlikoff MI, Chen J, Chien K, Gu H, Guan JL, Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. J Clin Invest. 2006 Jan;116(1):217-27 |
3 | J:134635 Peng X, Wu X, Druso JE, Wei H, Park AY, Kraus MS, Alcaraz A, Chen J, Chien S, Cerione RA, Guan JL, Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6638-43 |
1 | J:163221 Pereira JA, Benninger Y, Baumann R, Goncalves AF, Ozcelik M, Thurnherr T, Tricaud N, Meijer D, Fassler R, Suter U, Relvas JB, Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system. J Cell Biol. 2009 Apr 6;185(1):147-61 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
2* | J:253620 Pryce BR, Al-Zahrani KN, Dufresne S, Belkina N, Labreche C, Patino-Lopez G, Frenette J, Shaw S, Sabourin LA, Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness. Skelet Muscle. 2017 Feb 2;7(1):3 |
2* | J:245204 Rashid M, Belmont J, Carpenter D, Turner CE, Olson EC, Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development. 2017 Nov 01;144(21):4002-4014 |
1 | J:272907 Rojas T, Cheng W, Gao Z, Liu X, Wang Y, Malla AP, Chin AC, Romer LH, Snyder SH, Fu C, Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3278-3287 |
1 | J:124110 Schmidt M, Paes K, De Maziere A, Smyczek T, Yang S, Gray A, French D, Kasman I, Klumperman J, Rice DS, Ye W, EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution. Development. 2007 Aug;134(16):2913-23 |
3 | J:99637 Shen TL, Park AY, Alcaraz A, Peng X, Jang I, Koni P, Flavell RA, Gu H, Guan JL, Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis. J Cell Biol. 2005 Jun 20;169(6):941-52 |
1 | J:133673 Shim SY, Wang J, Asada N, Neumayer G, Tran HC, Ishiguro K, Sanada K, Nakatani Y, Nguyen MD, Protein 600 is a microtubule/endoplasmic reticulum-associated protein in CNS neurons. J Neurosci. 2008 Apr 2;28(14):3604-14 |
1 | J:165815 Smeeton J, Zhang X, Bulus N, Mernaugh G, Lange A, Karner CM, Carroll TJ, Fassler R, Pozzi A, Rosenblum ND, Zent R, Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development. Development. 2010 Oct;137(19):3233-43 |
1 | J:121342 Song B, Haycraft CJ, Seo HS, Yoder BK, Serra R, Development of the post-natal growth plate requires intraflagellar transport proteins. Dev Biol. 2007 May 1;305(1):202-16 |
1 | J:155959 Srinivasan R, Zabuawala T, Huang H, Zhang J, Gulati P, Fernandez S, Karlo JC, Landreth GE, Leone G, Ostrowski MC, Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis. PLoS One. 2009;4(12):e8283 |
1 | J:272614 Suzuki A, Minamide R, Iwata J, WNT/beta-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development. Development. 2018 Nov 27;145(23):dev168351 |
3* | J:194960 Tai G, Hohenstein P, Davies JA, FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique. Biol Open. 2013;2:416-423 |
1 | J:229358 Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU, Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Exp Eye Res. 2014 Apr;121:130-42 |
5* | J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23 |
1 | J:235538 Tomann P, Paus R, Millar SE, Scheidereit C, Schmidt-Ullrich R, Lhx2 is a direct NF-kappaB target gene that promotes primary hair follicle placode down-growth. Development. 2016 May 1;143(9):1512-22 |
1 | J:182249 Tsukahara Y, Tanaka M, Miyajima A, TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development. PLoS One. 2011;6(12):e28607 |
2 | J:175239 Valiente M, Ciceri G, Rico B, Marin O, Focal adhesion kinase modulates radial glia-dependent neuronal migration through connexin-26. J Neurosci. 2011 Aug 10;31(32):11678-91 |
3 | J:152558 Vallejo-Illarramendi A, Zang K, Reichardt LF, Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development. J Clin Invest. 2009 Aug;119(8):2218-30 |
3 | J:91730 Verma-Kurvari S, Parada LF, Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Dev Dyn. 2004 Aug;230(4):660-5 |
1 | J:270995 Wang L, Tanaka Y, Wang D, Morikawa M, Zhou R, Homma N, Miyamoto Y, Hirokawa N, The Atypical Kinesin KIF26A Facilitates Termination of Nociceptive Responses by Sequestering Focal Adhesion Kinase. Cell Rep. 2018 Sep 11;24(11):2894-2907 |
1 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1 | J:224370 Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G, Kindlin-2 controls TGF-beta signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015;6:7531 |
7* | J:85235 Xie Z, Sanada K, Samuels BA, Shih H, Tsai LH, Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. Cell. 2003 Aug 22;114(4):469-82 |
1 | J:271268 Yui S, Azzolin L, Maimets M, Pedersen MT, Fordham RP, Hansen SL, Larsen HL, Guiu J, Alves MRP, Rundsten CF, Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB, YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018 Jan 4;22(1):35-49.e7 |
3 | J:113594 Zhai J, Lin H, Nie Z, Wu J, Canete-Soler R, Schlaepfer WW, Schlaepfer DD, Direct interaction of focal adhesion kinase with p190RhoGEF. J Biol Chem. 2003 Jul 4;278(27):24865-73 |
3 | J:328946 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Volk RF, Hofmann KL, Zaro B, Chuang PT, Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions. PLoS Biol. 2022 Aug;20(8):e3001759 |
1 | J:153635 Zhang X, Mernaugh G, Yang DH, Gewin L, Srichai MB, Harris RC, Iturregui JM, Nelson RD, Kohan DE, Abrahamson D, Fassler R, Yurchenco P, Pozzi A, Zent R, beta1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity. Development. 2009 Oct;136(19):3357-66 |
1 | J:352076 Zhu M, Gu B, Thomas EC, Huang Y, Kim YK, Tao H, Yung TM, Chen X, Zhang K, Woolaver EK, Nevin MR, Huang X, Winklbauer R, Rossant J, Sun Y, Hopyan S, A fibronectin gradient remodels mixed-phase mesoderm. Sci Adv. 2024 Jul 19;10(29):eadl6366 |
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last database update 11/12/2024 MGI 6.24 |
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