Gene Expression Literature Summary

• Symbol: Fgf6
• Name: fibroblast growth factor 6
• ID: MGI:95520

40 matching records from 40 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7.5	E8.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)										1				1				1
In situ RNA (section)	2	1	2	3		5	1	4		5		5		8		3	1	5		1		1	1	4
In situ RNA (whole mount)				1		8		3		1		1		1
In situ reporter (knock in)						1		1		1						1
Western blot												1
RT-PCR				1	1		1	4	2	5	2	3	3	4	1	1	2	2	1	3	1	3	1	8
cDNA clones														1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgf6  fibroblast growth factor 6   (Synonyms: Fgf-6)
Results	Reference
1	J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507
3*	J:67307 Bachler M, Neubuser A, Expression of members of the Fgf family and their receptors during midfacial development. Mech Dev. 2001 Feb;100(2):313-6
3	J:95359 Brent AE, Braun T, Tabin CJ, Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development. Development. 2005 Feb;132(3):515-28
1*	J:127524 Davie JK, Cho JH, Meadows E, Flynn JM, Knapp JR, Klein WH, Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev Biol. 2007 Nov 15;311(2):650-64
10*	J:12606 deLapeyriere O, Ollendorff V, Planche J, Ott MO, Pizette S, Coulier F, Birnbaum D, Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo. Development. 1993 Jun;118(2):601-11
7*	J:82773 Dichmann DS, Miller CP, Jensen J, Scott Heller R, Serup P, Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas. Dev Dyn. 2003 Apr;226(4):663-74
12*	J:231094 Du W, Prochazka J, Prochazkova M, Klein OD, Expression of FGFs during early mouse tongue development. Gene Expr Patterns. 2016 Mar;20(2):81-7
5*	J:42542 Fiore F, Planche J, Gibier P, Sebille A, deLapeyriere O, Birnbaum D, Apparent normal phenotype of Fgf6-/- mice. Int J Dev Biol. 1997 Aug;41(4):639-42
2*	J:42574 Floss T, Arnold HH, Braun T, A role for FGF-6 in skeletal muscle regeneration. Genes Dev. 1997 Aug 15;11(16):2040-51
3*	J:30824 Grass S, Arnold HH, Braun T, Alterations in somite patterning of Myf-5-deficient mice: a possible role for FGF-4 and FGF-6. Development. 1996 Jan;122(1):141-50
2	J:98519 Grifone R, Demignon J, Houbron C, Souil E, Niro C, Seller MJ, Hamard G, Maire P, Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo. Development. 2005 May;132(9):2235-49
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:204192 Hadjab S, Franck MC, Wang Y, Sterzenbach U, Sharma A, Ernfors P, Lallemend F, A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. J Neurosci. 2013 Nov 6;33(45):17656-66
1*	J:76230 Hajihosseini MK, Heath JK, Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev. 2002 Apr;113(1):79-83
4	J:224277 Han A, Zhao H, Li J, Pelikan R, Chai Y, ALK5-mediated transforming growth factor beta signaling in neural crest cells controls craniofacial muscle development via tissue-tissue interactions. Mol Cell Biol. 2014 Aug;34(16):3120-31
6	J:184019 Han D, Zhao H, Parada C, Hacia JG, Bringas P Jr, Chai Y, A TGFbeta-Smad4-Fgf6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development. Development. 2012 May;139(9):1640-50
10*	J:13172 Han JK, Martin GR, Embryonic expression of Fgf-6 is restricted to the skeletal muscle lineage. Dev Biol. 1993 Aug;158(2):549-54
2	J:157252 Hiramatsu R, Harikae K, Tsunekawa N, Kurohmaru M, Matsuo I, Kanai Y, FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation. Development. 2010 Jan;137(2):303-12
3	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
2	J:235489 Li J, Wang Q, Cui Y, Yang X, Li Y, Zhang X, Qiu M, Zhang Z, Zhang Z, Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin. PLoS One. 2015;10(5):e0128006
1	J:301249 Lopez-Delgado AC, Delgado I, Cadenas V, Sanchez-Cabo F, Torres M, Axial skeleton anterior-posterior patterning is regulated through feedback regulation between Meis transcription factors and retinoic acid. Development. 2021 Jan 4;148(1):dev193813
1*	J:103128 Machka C, Kersten M, Zobawa M, Harder A, Horsch M, Halder T, Lottspeich F, Hrabe de Angelis M, Beckers J, Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling. Gene Expr Patterns. 2005 Dec;6(1):94-101
3	J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021
2*	J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109
4*	J:311146 Murata H, Sunohara M, Sato I, Expression of DMP1 in the developing mouse tongue embryo. Ann Anat. 2015 Jul;200:136-48
2	J:45221 Ozawa K, Seo M, Imamura T, A quantitative method for evaluation of FGF family and FGF receptor family gene expression by RT-PCR. Brain Res Brain Res Protoc. 1997 Aug;1(3):211-6
7*	J:35179 Ozawa K, Uruno T, Miyakawa K, Seo M, Imamura T, Expression of the fibroblast growth factor family and their receptor family genes during mouse brain development. Brain Res Mol Brain Res. 1996 Sep 5;41(1-2):279-88
4*	J:29279 Patapoutian A, Yoon JK, Miner JH, Wang S, Stark K, Wold B, Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome. Development. 1995 Oct;121(10):3347-58
2*	J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8
2	J:176344 Ratzka A, Baron O, Grothe C, FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system. PLoS One. 2011;6(8):e23564
1	J:90060 Sil AK, Maeda S, Sano Y, Roop DR, Karin M, IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature. 2004 Apr 8;428(6983):660-4
2	J:119030 Spater D, Hill TP, O'sullivan RJ, Gruber M, Conner DA, Hartmann C, Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development. 2006 Aug;133(15):3039-49
2	J:193313 Takase HM, Itoh T, Ino S, Wang T, Koji T, Akira S, Takikawa Y, Miyajima A, FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 2013 Jan 15;27(2):169-81
1*	J:65301 Tallquist MD, Weismann KE, Hellstrom M, Soriano P, Early myotome specification regulates PDGFA expression and axial skeleton development. Development. 2000 Dec;127(23):5059-70
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:90044 Vidrich A, Buzan JM, Ilo C, Bradley L, Skaar K, Cohn SM, Fibroblast growth factor receptor-3 is expressed in undifferentiated intestinal epithelial cells during murine crypt morphogenesis. Dev Dyn. 2004 May;230(1):114-23
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*	J:31611 Wang Y, Schnegelsberg PN, Dausman J, Jaenisch R, Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin. Nature. 1996 Feb 29;379(6568):823-5
3*	J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072
1*	J:101025 Yaylaoglu MB, Titmus A, Visel A, Alvarez-Bolado G, Thaller C, Eichele G, Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform. Dev Dyn. 2005 Oct;234(2):371-86