Gene Expression Literature Summary

• Symbol: Folr1
• Name: folate receptor alpha
• ID: MGI:95568

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E3.5	E8	E8.5	E9	E9.5	E10	E10.5	E12	E12.5	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)						1		2		2		2		1		1		1	1		1		5
In situ RNA (section)							1	1		1		1		1	3	1		1	1				2
In situ RNA (whole mount)							1	1	1	1		1											1
In situ reporter (knock in)																							1
Northern blot											1
Western blot		1				1																	2
RT-PCR	3	4	2	2	1	3				2		1		1								1	5
RNase protection							1		1		1		1				1			1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Folr1  folate receptor alpha   (Synonyms: FBP1, folate-binding protein 1, folate receptor [a], Folbp-1, Folbp1)
Results	Reference
7*	J:53758 Barber RC, Bennett GD, Greer KA, Finnell RH, Expression patterns of folate binding proteins one and two in the developing mouse embryo. Mol Genet Metab. 1999 Jan;66(1):31-9
7	J:184371 Cherukad J, Wainwright V, Watson ED, Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development. Placenta. 2012 May;33(5):440-8
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
7*	J:203885 Kooistra M, Trasler JM, Baltz JM, Folate transport in mouse cumulus-oocyte complexes and preimplantation embryos. Biol Reprod. 2013 Sep;89(3):63
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
10	J:214694 Kur E, Mecklenburg N, Cabrera RM, Willnow TE, Hammes A, LRP2 mediates folate uptake in the developing neural tube. J Cell Sci. 2014 May 15;127(Pt 10):2261-8
1*	J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
1*	J:193822 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S, Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
9	J:319636 Meredith M, MacNeil AH, Trasler JM, Baltz JM, Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size. Biol Reprod. 2016 Jun;94(6):125
1	J:57765 Piedrahita JA, Oetama B, Bennett GD, van Waes J, Kamen BA, Richardson J, Lacey SW, Anderson RG, Finnell RH, Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet. 1999 Oct;23(2):228-32
9	J:81142 Saitsu H, Ishibashi M, Nakano H, Shiota K, Spatial and temporal expression of folate-binding protein 1 (Fbp1) is closely associated with anterior neural tube closure in mice. Dev Dyn. 2003 Jan;226(1):112-7
8*	J:310862 Strandgaard T, Foder S, Heuck A, Ernst E, Nielsen MS, Lykke-Hartmann K, Maternally Contributed Folate Receptor 1 Is Expressed in Ovarian Follicles and Contributes to Preimplantation Development. Front Cell Dev Biol. 2017;5:89
1	J:28346 Taylor LE, Bennett GD, Finnell RH, Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J Craniofac Genet Dev Biol. 1995 Jan-Mar;15(1):13-25
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:334334 Zhang M, Salbaum JM, Jones S, Burk D, Kappen C, Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity. Front Cell Dev Biol. 2023;11:1073807
3	J:344223 Zhang W, Zhang R, Wu L, Zhu C, Zhang C, Xu C, Zhao S, Liu X, Guo T, Lu Y, Gao Z, Yu X, Li L, Chen ZJ, Qin Y, Jiao X, NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance. Cell Rep. 2023 Dec 26;42(12):113531
3	J:124492 Zhu H, Wlodarczyk BJ, Scott M, Yu W, Merriweather M, Gelineau-van Waes J, Schwartz RJ, Finnell RH, Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol. 2007 Apr;79(4):257-68