Gene Expression Literature Summary

• Symbol: Gabra6
• Name: gamma-aminobutyric acid type A receptor subunit alpha 6
• ID: MGI:95618

22 matching records from 22 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E18	E18.5	P
Immunohistochemistry (section)		1		1					12
In situ RNA (section)	2		1	1	2	1		1	4
In situ reporter (knock in)									1
Northern blot							1		1
RT-PCR									3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gabra6  gamma-aminobutyric acid type A receptor subunit alpha 6   (Synonyms: alpha6, GABA-ARalpha6, Gabra-6)
Results	Reference
1*	J:91624 Aller MI, Jones A, Merlo D, Paterlini M, Meyer AH, Amtmann U, Brickley S, Jolin HE, McKenzie AN, Monyer H, Farrant M, Wisden W, Cerebellar granule cell Cre recombinase expression. Genesis. 2003 Jun;36(2):97-103
1	J:96910 Blaess S, Graus-Porta D, Belvindrah R, Radakovits R, Pons S, Littlewood-Evans A, Senften M, Guo H, Li Y, Miner JH, Reichardt LF, Muller U, Beta1-integrins are critical for cerebellar granule cell precursor proliferation. J Neurosci. 2004 Mar 31;24(13):3402-12
1	J:170488 Blank MC, Grinberg I, Aryee E, Laliberte C, Chizhikov VV, Henkelman RM, Millen KJ, Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis. Development. 2011 Mar;138(6):1207-16
1	J:119485 Friedel RH, Kerjan G, Rayburn H, Schuller U, Sotelo C, Tessier-Lavigne M, Chedotal A, Plexin-B2 controls the development of cerebellar granule cells. J Neurosci. 2007 Apr 4;27(14):3921-32
3	J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
1	J:99183 Heglind M, Cederberg A, Aquino J, Lucas G, Ernfors P, Enerback S, Lack of the central nervous system- and neural crest-expressed forkhead gene foxs1 affects motor function and body weight. Mol Cell Biol. 2005 Jul;25(13):5616-25
1	J:228845 Kim E, Wang Y, Kim SJ, Bornhorst M, Jecrois ES, Anthony TE, Wang C, Li YE, Guan JL, Murphy GG, Zhu Y, Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. Elife. 2014;3
1	J:286844 Kim J, Kim K, Mo JS, Lee Y, Atm deficiency in the DNA polymerase beta null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation. Nucleic Acids Res. 2020 Apr 17;48(7):3678-3691
1	J:149816 Koirala S, Jin Z, Piao X, Corfas G, GPR56-regulated granule cell adhesion is essential for rostral cerebellar development. J Neurosci. 2009 Jun 10;29(23):7439-49
1	J:172420 Lancaster MA, Gopal DJ, Kim J, Saleem SN, Silhavy JL, Louie CM, Thacker BE, Williams Y, Zaki MS, Gleeson JG, Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Nat Med. 2011 Jun;17(6):726-31
2*	J:37685 Lin X, Shah S, Bulleit RF, The expression of MEF2 genes is implicated in CNS neuronal differentiation. Brain Res Mol Brain Res. 1996 Dec;42(2):307-16
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:167973 Maier V, Jolicoeur C, Rayburn H, Takegahara N, Kumanogoh A, Kikutani H, Tessier-Lavigne M, Wurst W, Friedel RH, Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development. Mol Cell Neurosci. 2011 Feb;46(2):419-31
1	J:45673 McAndrew PE, Frostholm A, Evans JE, Zdilar D, Goldowitz D, Chiu IM, Burghes AH, Rotter A, Novel receptor protein tyrosine phosphatase (RPTPrho) and acidic fibroblast growth factor (FGF-1) transcripts delineate a rostrocaudal boundary in the granule cell layer of the murine cerebellar cortex. J Comp Neurol. 1998 Feb 22;391(4):444-55
1	J:221789 Mo J, Kim CH, Lee D, Sun W, Lee HW, Kim H, Early growth response 1 (Egr-1) directly regulates GABAA receptor alpha2, alpha4, and theta subunits in the hippocampus. J Neurochem. 2015 May;133(4):489-500
1	J:151542 Murga M, Bunting S, Montana MF, Soria R, Mulero F, Canamero M, Lee Y, McKinnon PJ, Nussenzweig A, Fernandez-Capetillo O, A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. Nat Genet. 2009 Aug;41(8):891-8
1	J:187345 Piper M, Harris L, Barry G, Heng YH, Plachez C, Gronostajski RM, Richards LJ, Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum. J Comp Neurol. 2011 Dec 1;519(17):3532-48
2	J:103333 Temple JL, Wray S, Developmental changes in GABA receptor subunit composition within the gonadotrophin-releasing hormone-1 neuronal system. J Neuroendocrinol. 2005 Sep;17(9):591-9
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:173787 Wang L, Nomura M, Goto Y, Tanaka K, Sakamoto R, Abe I, Sakamoto S, Shibata A, Enciso PL, Adachi M, Ohnaka K, Kawate H, Takayanagi R, Smad2 protein disruption in the central nervous system leads to aberrant cerebellar development and early postnatal ataxia in mice. J Biol Chem. 2011 May 27;286(21):18766-74
1	J:194150 Wright KM, Lyon KA, Leung H, Leahy DJ, Ma L, Ginty DD, Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 2012 Dec 6;76(5):931-44
1	J:214730 Zindy F, Kawauchi D, Lee Y, Ayrault O, Ben Merzoug L, McKinnon PJ, Ventura A, Roussel MF, Role of the miR-17 approximately 92 cluster family in cerebellar and medulloblastoma development. Biol Open. 2014;3(7):597-605