Gene Expression Literature Summary

• Symbol: Gabrb3
• Name: GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3
• ID: MGI:95621

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)	1		3			3		1	2	1			4
In situ RNA (section)	1	1	1	1	5	1	1	2		1	1		4
In situ RNA (whole mount)						1
Northern blot					2	1		2	1		2		1
Western blot												1	3
RT-PCR			3		2	1		1	2				4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gabrb3  GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3   (Synonyms: A230092K12Rik, beta3, Gabrb-3)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
4*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
8	J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28
5*	J:12553 Culiat CT, Stubbs L, Nicholls RD, Montgomery CS, Russell LB, Johnson DK, Rinchik EM, Concordance between isolated cleft palate in mice and alterations within a region including the gene encoding the beta 3 subunit of the type A gamma-aminobutyric acid receptor. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5105-9
1	J:77469 Davis AM, Henion TR, Tobet SA, Gamma-aminobutyric acidB receptors and the development of the ventromedial nucleus of the hypothalamus. J Comp Neurol. 2002 Jul 29;449(3):270-80
1	J:79217 Dellovade TL, Davis AM, Ferguson C, Sieghart W, Homanics GE, Tobet SA, GABA influences the development of the ventromedial nucleus of the hypothalamus. J Neurobiol. 2001 Dec;49(4):264-76
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:270507 Funato N, Yanagisawa H, Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans. Arch Oral Biol. 2018 Nov;95:149-155
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
2	J:164010 Jiang YH, Pan Y, Zhu L, Landa L, Yoo J, Spencer C, Lorenzo I, Brilliant M, Noebels J, Beaudet AL, Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. PLoS One. 2010;5(8)
8*	J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41
1	J:257839 Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabo G, Jain RK, Kohling R, Vasudevan A, Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Cell Res. 2018 Feb;28(2):221-248
1*	J:160811 McDowell KA, Hutchinson AN, Wong-Goodrich SJ, Presby MM, Su D, Rodriguiz RM, Law KC, Williams CL, Wetsel WC, West AE, Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. J Neurosci. 2010 Jun 2;30(22):7453-65
1	J:306874 McSweeney C, Dong F, Chen M, Vitale J, Xu L, Crowley N, Luscher B, Zou D, Mao Y, Full function of exon junction complex factor, Rbm8a, is critical for interneuron development. Transl Psychiatry. 2020 Nov 5;10(1):379
1	J:221789 Mo J, Kim CH, Lee D, Sun W, Lee HW, Kim H, Early growth response 1 (Egr-1) directly regulates GABAA receptor alpha2, alpha4, and theta subunits in the hippocampus. J Neurochem. 2015 May;133(4):489-500
2*	J:158888 Oh WJ, Westmoreland JJ, Summers R, Condie BG, Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice. PLoS One. 2010;5(3):e9758
1*	J:56295 Ohshima T, Gilmore EC, Longenecker G, Jacobowitz DM, Brady RO, Herrup K, Kulkarni AB, Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous. J Neurosci. 1999 Jul 15;19(14):6017-26
1	J:354049 Pulcrano S, De Gregorio R, De Sanctis C, Volpicelli F, Piscitelli RM, Speranza L, Perrone-Capano C, di Porzio U, Caiazzo M, Martini A, Giacomet C, Medina D, Awatramani R, Viggiano D, Federici M, Mercuri NB, Guatteo E, Bellenchi GC, miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network. J Neurosci. 2023 Nov 29;43(48):8104-8125
1*	J:177918 Quille ML, Carat S, Quemener-Redon S, Hirchaud E, Baron D, Benech C, Guihot J, Placet M, Mignen O, Ferec C, Houlgatte R, Friocourt G, High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies. PLoS One. 2011;6(9):e25181
2*	J:52209 Serpinskaya AS, Feng GP, Sanes JR, Craig AM, Synapse formation by hippocampal neurons from agrin- deficient mice. Dev Biol. 1999 JAN 1;205(1):65-78
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2*	J:52383 Tobet SA, Henderson RG, Whiting PJ, Sieghart W, Special relationship of gamma-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development. J Comp Neurol. 1999 Mar 1;405(1):88-98
7	J:350003 Zavalin K, Hassan A, Zhang Y, Khera Z, Lagrange AH, Region and layer-specific expression of GABA(A) receptor isoforms and KCC2 in developing cortex. Front Cell Neurosci. 2024;18:1390742