Gene Expression Literature Summary

• Symbol: Gabrg2
• Name: gamma-aminobutyric acid type A receptor, subunit gamma 2
• ID: MGI:95623

30 matching records from 30 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E19.5	P
Immunohistochemistry (section)			1		1			2			1	4
In situ RNA (section)	2	1	5		2		3			1		6
Western blot						1					1	6
RT-PCR		2	1	1	4		1	3	2	1		9
cDNA clones							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gabrg2  gamma-aminobutyric acid type A receptor, subunit gamma 2   (Synonyms: GABAA-R, Gabrg-2, gamma2)
Results	Reference
3	J:242531 Bedogni F, Cobolli Gigli C, Pozzi D, Rossi RL, Scaramuzza L, Rossetti G, Pagani M, Kilstrup-Nielsen C, Matteoli M, Landsberger N, Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms. Cereb Cortex. 2016 Jun;26(6):2517-2529
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
2	J:100324 Bulfone A, Carotenuto P, Faedo A, Aglio V, Garzia L, Bello AM, Basile A, Andre A, Cocchia M, Guardiola O, Ballabio A, Rubenstein JL, Zollo M, Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. J Neurosci. 2005 Aug 17;25(33):7586-600
2	J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28
2	J:117140 Cheng Q, Yeh PW, Yeh HH, Cajal-Retzius cells switch from expressing gamma-less to gamma-containing GABA receptors during corticogenesis. Eur J Neurosci. 2006 Oct;24(8):2145-51
1*	J:161372 Cheung CC, Yang C, Berger T, Zaugg K, Reilly P, Elia AJ, Wakeham A, You-Ten A, Chang N, Li L, Wan Q, Mak TW, Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABAA receptors. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11883-8
1	J:79217 Dellovade TL, Davis AM, Ferguson C, Sieghart W, Homanics GE, Tobet SA, GABA influences the development of the ventromedial nucleus of the hypothalamus. J Neurobiol. 2001 Dec;49(4):264-76
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:270507 Funato N, Yanagisawa H, Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans. Arch Oral Biol. 2018 Nov;95:149-155
1*	J:357551 Ge Y, Craig AM, Haploinsufficiency of GABA(A) Receptor-Associated Clptm1 Enhances Phasic and Tonic Inhibitory Neurotransmission, Suppresses Excitatory Synaptic Plasticity, and Impairs Memory. J Neurosci. 2024 Aug 7;44(32)
1	J:181631 Gehman LT, Meera P, Stoilov P, Shiue L, O'Brien JE, Meisler MH, Ares M Jr, Otis TS, Black DL, The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Genes Dev. 2012 Mar 1;26(5):445-60
3	J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
2	J:187349 Hu XL, Cheng X, Cai L, Tan GH, Xu L, Feng XY, Lu TJ, Xiong H, Fei J, Xiong ZQ, Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model. Cereb Cortex. 2011 Sep;21(9):2158-65
3*	J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27
2	J:256001 Jung EM, Moffat JJ, Liu J, Dravid SM, Gurumurthy CB, Kim WY, Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nat Neurosci. 2017 Dec;20(12):1694-1707
2*	J:58210 Kneussel M, Brandstatter JH, Laube B, Stahl S, Muller U, Betz H, Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice. J Neurosci. 1999 Nov 1;19(21):9289-97
1*	J:63409 Kneussel M, Haverkamp S, Fuhrmann JC, Wang H, Wassle H, Olsen RW, Betz H, The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8594-9
5*	J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41
2*	J:282974 Lee M, Liu YC, Chen C, Lu CH, Lu ST, Huang TN, Hsu MT, Hsueh YP, Cheng PL, Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain. J Cell Biol. 2020 Feb 3;219(2)
2	J:207976 Li Q, Zheng S, Han A, Lin CH, Stoilov P, Fu XD, Black DL, The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. Elife. 2014;3:e01201
1	J:333829 Lopez-Tello J, Sferruzzi-Perri AN, Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age. Front Endocrinol (Lausanne). 2023;14:1116770
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:160811 McDowell KA, Hutchinson AN, Wong-Goodrich SJ, Presby MM, Su D, Rodriguiz RM, Law KC, Williams CL, Wetsel WC, West AE, Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. J Neurosci. 2010 Jun 2;30(22):7453-65
4	J:355330 Neumann E, Cramer T, Acuna MA, Scheurer L, Beccarini C, Luscher B, Wildner H, Zeilhofer HU, gamma1 GABA(A) Receptors in Spinal Nociceptive Circuits. J Neurosci. 2024 Oct 9;44(41)
1	J:340358 Oh H, Lee S, Oh Y, Kim S, Kim YS, Yang Y, Choi W, Yoo YE, Cho H, Lee S, Yang E, Koh W, Won W, Kim R, Lee CJ, Kim H, Kang H, Kim JY, Ku T, Paik SB, Kim E, Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice. Nat Commun. 2023 Jun 15;14(1):3547
1*	J:249826 Tanabe Y, Naito Y, Vasuta C, Lee AK, Soumounou Y, Linhoff MW, Takahashi H, IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2alpha. Nat Commun. 2017 Sep 01;8(1):408
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:266486 Weyn-Vanhentenryck SM, Feng H, Ustianenko D, Duffie R, Yan Q, Jacko M, Martinez JC, Goodwin M, Zhang X, Hengst U, Lomvardas S, Swanson MS, Zhang C, Precise temporal regulation of alternative splicing during neural development. Nat Commun. 2018 Jun 6;9(1):2189
1*	J:327184 Xiao Z, Liu S, Li Z, Cui J, Wang H, Wang Z, Ren Q, Xia L, Wang Z, Li Y, The Maternal Microbiome Programs the m(6)A Epitranscriptome of the Mouse Fetal Brain and Intestine. Front Cell Dev Biol. 2022;10:882994
6	J:350003 Zavalin K, Hassan A, Zhang Y, Khera Z, Lagrange AH, Region and layer-specific expression of GABA(A) receptor isoforms and KCC2 in developing cortex. Front Cell Neurosci. 2024;18:1390742