Gene Expression Literature Summary

• Symbol: Gli2
• Name: GLI-Kruppel family member GLI2
• ID: MGI:95728

280 matching records from 280 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1.5	E2	E5.5	E6.5	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)				1	1	2	1	2	3		7		1		1		1		3		2	1	3		1	2		1	2
In situ RNA (section)			1	1	1	1	9	2	16	2	14	4	14	3	11	3	12	4	19	2	13	2	7	5	1	6		2	17
Immunohistochemistry (whole mount)																												1
In situ RNA (whole mount)					1	2	4	3	8	1	14	4	10	3	9		6		4		5		1			1		3	1
In situ reporter (knock in)					1	1	3		2		1	1	1		2		1		2		1		2			1			4
Northern blot							1		1		2		1		2		1	2	1		2		2	2		1	1		3
Western blot							1	2	13		21	2	9		4		4		4				1		1	1		4	3
RT-PCR	1	1					3		10		7	1	8	2	12	1	14	2	14		17		9	9	1	13		4	34
cDNA clones							1		1		1	1	1	1	2		1												3
RNase protection																		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gli2  GLI-Kruppel family member GLI2
Results	Reference
1	J:316170 Agrawal V, Kim DY, Kwon YG, Hhip regulates tumor-stroma-mediated upregulation of tumor angiogenesis. Exp Mol Med. 2017 Jan 27;49(1):e289
1	J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16)
1	J:309392 Amano K, Densmore MJ, Lanske B, Conditional Deletion of Indian Hedgehog in Limb Mesenchyme Results in Complete Loss of Growth Plate Formation but Allows Mature Osteoblast Differentiation. J Bone Miner Res. 2015 Dec;30(12):2262-72
4*	J:79392 Bai CB, Auerbach W, Lee JS, Stephen D, Joyner AL, Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development. 2002 Oct;129(20):4753-61
3*	J:73074 Bai CB, Joyner AL, Gli1 can rescue the in vivo function of Gli2. Development. 2001 Dec;128(24):5161-72
3	J:181293 Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, Page KM, Briscoe J, Ribes V, Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell. 2012 Jan 20;148(1-2):273-84
1	J:203703 Barakat B, Yu L, Lo C, Vu D, De Luca E, Cain JE, Martelotto LG, Dedhar S, Sadler AJ, Wang D, Watkins DN, Hannigan GE, Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling. EMBO Rep. 2013 Sep;14(9):837-44
3	J:173724 Barsoum I, Yao HH, Redundant and differential roles of transcription factors gli1 and gli2 in the development of mouse fetal Leydig cells. Biol Reprod. 2011 May;84(5):894-9
1*	J:59288 Baur ST, Mai JJ, Dymecki SM, Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity. Development. 2000 Feb;127(3):605-19
3*	J:70831 Becker MB, Zulch A, Bosse A, Gruss P, Irx1 and Irx2 expression in early lung development. Mech Dev. 2001 Aug;106(1-2):155-8
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
2	J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90
1	J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39
2*	J:259558 Bhattacharyya S, Rainey MA, Arya P, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Gelineau-van Waes J, Band V, Band H, Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016 Feb 17;6:20727
3	J:121232 Bok J, Dolson DK, Hill P, Ruther U, Epstein DJ, Wu DK, Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear. Development. 2007 May;134(9):1713-22
1	J:279187 Bolte C, Ren X, Tomley T, Ustiyan V, Pradhan A, Hoggatt A, Kalin TV, Herring BP, Kalinichenko VV, Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development. J Biol Chem. 2015 Mar 20;290(12):7563-75
2	J:110699 Boras-Granic K, Chang H, Grosschedl R, Hamel PA, Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland. Dev Biol. 2006 Jul 1;295(1):219-31
1	J:139130 Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P, Town T, Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13127-32
7*	J:45211 Buscher D, Ruther U, Expression profile of Gli family members and Shh in normal and mutant mouse limb development. Dev Dyn. 1998 Jan;211(1):88-96
1*	J:87223 Buttitta L, Mo R, Hui CC, Fan CM, Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. Development. 2003 Dec;130(25):6233-43
1	J:239074 Cai H, Liu A, Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14751-14756
2	J:251822 Cai H, Liu A, Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord. Dev Biol. 2017 Dec 1;432(1):72-85
5*	J:171293 Campbell GR, Baudhuin A, Vranizan K, Ngai J, Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. Mol Cell Neurosci. 2011 Feb;46(2):548-61
3	J:150524 Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA, Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17
1	J:236864 Chang CF, Chang YT, Millington G, Brugmann SA, Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline. PLoS Genet. 2016 Nov;12(11):e1006351
1	J:151923 Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT, Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev. 2009 Aug 15;23(16):1910-28
1	J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827
1	J:141874 Cheng W, Yeung CK, Ng YK, Zhang JR, Hui CC, Kim PC, Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterning. J Urol. 2008;180(4):1543-50
3	J:152259 Cheung HO, Zhang X, Ribeiro A, Mo R, Makino S, Puviindran V, Law KK, Briscoe J, Hui CC, The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci Signal. 2009;2(76):ra29
2	J:155992 Ching S, Vilain E, Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia. Genesis. 2009 Sep;47(9):628-37
3	J:138713 Cho A, Ko HW, Eggenschwiler JT, FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism. Dev Biol. 2008 Sep 1;321(1):27-39
4	J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037
1	J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48
1*	J:153142 Clement CA, Kristensen SG, Mollgard K, Pazour GJ, Yoder BK, Larsen LA, Christensen ST, The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation. J Cell Sci. 2009 Sep 1;122(Pt 17):3070-82
1	J:197449 Coles GL, Ackerman KG, Kif7 is required for the patterning and differentiation of the diaphragm in a model of syndromic congenital diaphragmatic hernia. Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1898-905
1	J:228894 Coles GL, Baglia LA, Ackerman KG, KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms. PLoS Genet. 2015 Oct;11(10):e1005525
2	J:291480 Constable S, Long AB, Floyd KA, Schurmans S, Caspary T, The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling. Development. 2020 Feb 3;147(3):dev183301
3	J:284605 Coquenlorge S, Yin WC, Yung T, Pan J, Zhang X, Mo R, Belik J, Hui CC, Kim TH, GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis. Cell Rep. 2019 Jun 4;27(10):3006-3018.e4
3	J:94461 Corrales JD, Rocco GL, Blaess S, Guo Q, Joyner AL, Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development. 2004 Nov;131(22):5581-90
1	J:167534 Cui C, Chatterjee B, Francis D, Yu Q, SanAgustin JT, Francis R, Tansey T, Henry C, Wang B, Lemley B, Pazour GJ, Lo CW, Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome. Dis Model Mech. 2011 Jan;4(1):43-56
1	J:205269 Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Liu X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW, Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013 Nov;11(11):e1001720
1	J:220990 Cunningham D, DeBarber AE, Bir N, Binkley L, Merkens LS, Steiner RD, Herman GE, Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development. Hum Mol Genet. 2015 May 15;24(10):2808-25
4	J:171198 Cwinn MA, Mazerolle C, McNeill B, Ringuette R, Thurig S, Hui CC, Wallace VA, Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina. J Neurosci. 2011 Mar 30;31(13):5169-80
1	J:20187 Dahmane N, Ruiz-i-Altaba A, Sonic hedgehog regulates the growth and patterning of the cerebellum. Development. 1999 Jun;126(14):3089-100
2*	J:73075 Dahmane N, Sanchez P, Gitton Y, Palma V, Sun T, Beyna M, Weiner H, Ruiz i Altaba A, The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development. 2001 Dec;128(24):5201-12
1	J:205544 Dai D, Li L, Huebner A, Zeng H, Guevara E, Claypool DJ, Liu A, Chen J, Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia. Cell Death Differ. 2013 Jan;20(1):130-8
2	J:173143 Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li AG, Finnell RH, Roop DR, Chen J, Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol. 2011 Feb;131(2):302-10
2	J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73
1*	J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560
1	J:65294 Dassule HR, Lewis P, Bei M, Maas R, McMahon AP, Sonic hedgehog regulates growth and morphogenesis of the tooth. Development. 2000 Nov;127(22):4775-85
5	J:195713 DeSouza KR, Saha M, Carpenter AR, Scott M, McHugh KM, Analysis of the Sonic Hedgehog signaling pathway in normal and abnormal bladder development. PLoS One. 2013;8(1):e53675
1	J:189258 Dey J, Ditzler S, Knoblaugh SE, Hatton BA, Schelter JM, Cleary MA, Mecham B, Rorke-Adams LB, Olson JM, A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model. Mol Cell Biol. 2012 Oct;32(20):4104-15
2	J:313289 Dias JM, Alekseenko Z, Jeggari A, Boareto M, Vollmer J, Kozhevnikova M, Wang H, Matise MP, Alexeyenko A, Iber D, Ericson J, A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells. Sci Adv. 2020 Sep;6(38)
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*	J:49164 Ding Q, Motoyama J, Gasca S, Mo R, Sasaki H, Rossant J, Hui CC, Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development. 1998 Jul;125(14):2533-43
3	J:139256 Driver EC, Pryor SP, Hill P, Turner J, Ruther U, Biesecker LG, Griffith AJ, Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci. 2008 Jul 16;28(29):7350-8
14*	J:186282 Du J, Fan Z, Ma X, Wu Y, Liu S, Gao Y, Wang J, Shen Y, Fan M, Wang S, Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development. Acta Histochem. 2012 Oct;114(6):620-5
2*	J:296137 Elliott KH, Chen X, Salomone J, Chaturvedi P, Schultz PA, Balchand SK, Servetas JD, Zuniga A, Zeller R, Gebelein B, Weirauch MT, Peterson KA, Brugmann SA, Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks. Elife. 2020 Oct 2;9:e56450
2	J:335088 Escuin S, Rose Raza-Knight S, Savery D, Gaston-Massuet C, Galea GL, Greene NDE, Copp AJ, Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse. Dis Model Mech. 2023 Mar 1;16(3)
1	J:173367 Ezratty EJ, Stokes N, Chai S, Shah AS, Williams SE, Fuchs E, A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development. Cell. 2011 Jun 24;145(7):1129-41
1	J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489
4	J:257526 Feuerstein M, Chleilat E, Khakipoor S, Michailidis K, Ophoven C, Roussa E, Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line. Cell Tissue Res. 2017 Nov;370(2):211-225
4	J:106158 Furimsky M, Wallace VA, Complementary Gli activity mediates early patterning of the mouse visual system. Dev Dyn. 2006 Mar;235(3):594-605
2	J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24
1*	J:132568 Glotzer DJ, Zelzer E, Olsen BR, Impaired skin and hair follicle development in Runx2 deficient mice. Dev Biol. 2008 Mar 15;315(2):459-73
1	J:153098 Goss AM, Tian Y, Tsukiyama T, Cohen ED, Zhou D, Lu MM, Yamaguchi TP, Morrisey EE, Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009 Aug;17(2):290-8
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
3	J:62920 Grimmond S, Hateren NV, Siggers P, Arkell R, Larder R, Soares MB, Bonaldo Md, Smith L, Tymowska-Lalanne Z, Wells C, Greenfield A, Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development. Hum Mol Genet. 2000 Jun 12;9(10):1553-60
8*	J:42454 Grindley JC, Bellusci S, Perkins D, Hogan BL, Evidence for the involvement of the Gli gene family in embryonic mouse lung development. Dev Biol. 1997 Aug 15;188(2):337-48
1	J:80081 Gritli-Linde A, Bei M, Maas R, Zhang XM, Linde A, McMahon AP, Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development. 2002 Dec;129(23):5323-37
1	J:117334 Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A, Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007 Jan;12(1):99-112
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:346579 Han B, Wang Y, Yue S, Zhang YH, Kuang L, Gao BB, Wang Y, Zhang Z, Pu X, Wang XF, Hui CC, Yu TT, Liu C, Cheng SY, Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis. JCI Insight. 2024 Feb 15;9(6)
1	J:186503 Han L, Pan Y, Wang B, Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo. J Biol Chem. 2012 Jun 8;287(24):20483-9
1*	J:72303 Haraguchi R, Mo R, Hui C, Motoyama J, Makino S, Shiroishi T, Gaffield W, Yamada G, Unique functions of Sonic hedgehog signaling during external genitalia development. Development. 2001 Nov;128(21):4241-50
1*	J:306168 Haraguchi R, Yamada G, Murashima A, Matsumaru D, Kitazawa R, Kitazawa S, New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development. Int J Mol Sci. 2021 Jan 26;22(3)
5	J:60109 Hardcastle Z, Hui CC, Sharpe PT, The Shh signalling pathway in early tooth development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):567-78
4*	J:49252 Hardcastle Z, Mo R, Hui CC, Sharpe PT, The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development. 1998 Aug;125(15):2803-11
1*	J:92504 Harfe BD, Scherz PJ, Nissim S, Tian H, McMahon AP, Tabin CJ, Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell. 2004 Aug 20;118(4):517-28
1	J:298641 Hasan MR, Takatalo M, Ma H, Rice R, Mustonen T, Rice DP, RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1. Elife. 2020 Jul 14;9:e55829
4	J:112460 Hatsell SJ, Cowin P, Gli3-mediated repression of Hedgehog targets is required for normal mammary development. Development. 2006 Sep;133(18):3661-70
2	J:227755 He X, Zhang L, Chen Y, Remke M, Shih D, Lu F, Wang H, Deng Y, Yu Y, Xia Y, Wu X, Ramaswamy V, Hu T, Wang F, Zhou W, Burns DK, Kim SH, Kool M, Pfister SM, Weinstein LS, Pomeroy SL, Gilbertson RJ, Rubin JB, Hou Y, Wechsler-Reya R, Taylor MD, Lu QR, The G protein alpha subunit Galphas is a tumor suppressor in Sonic hedgehog-driven medulloblastoma. Nat Med. 2014 Sep;20(9):1035-42
1*	J:66532 Hecksher-Sorensen J, Sharpe J, 3D confocal reconstruction of gene expression in mouse. Mech Dev. 2001 Jan;100(1):59-63
2*	J:186535 Herriges JC, Yi L, Hines EA, Harvey JF, Xu G, Gray PA, Ma Q, Sun X, Genome-scale study of transcription factor expression in the branching mouse lung. Dev Dyn. 2012 Sep;241(9):1432-53
1	J:58673 Heymer J, Ruther U, Syndactyly of Ft/+ mice correlates with an imbalance in bmp4 and fgf8 expression. Mech Dev. 1999 Nov;88(2):173-81
1	J:241569 Higashiyama H, Ozawa A, Sumitomo H, Uemura M, Fujino K, Igarashi H, Imaimatsu K, Tsunekawa N, Hirate Y, Kurohmaru M, Saijoh Y, Kanai-Azuma M, Kanai Y, Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia. Development. 2017 May 15;144(10):1906-1917
1	J:331486 Hirose T, Sugitani Y, Kurihara H, Kazama H, Kusaka C, Noda T, Takahashi H, Ohno S, PAR3 restricts the expansion of neural precursor cells by regulating hedgehog signaling. Development. 2022 Nov 1;149(21):dev199931
1*	J:245959 Ho UY, Wainwright BJ, Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation. Mech Dev. 2017 Oct;147:37-48
2	J:248771 Hoelzl MA, Heby-Henricson K, Gerling M, Dias JM, Kuiper RV, Trunkle C, Bergstrom A, Ericson J, Toftgard R, Teglund S, Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model. Dev Biol. 2017 Sep 1;429(1):132-146
2	J:309463 Hor CHH, Lo JCW, Cham ALS, Leong WY, Goh ELK, Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation. J Neurosci. 2021 Aug 11;41(32):6850-6863
3	J:104380 Hu MC, Mo R, Bhella S, Wilson CW, Chuang PT, Hui CC, Rosenblum ND, GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis. Development. 2006 Feb;133(3):569-78
5*	J:38297 Hughes DC, Allen J, Morley G, Sutherland K, Ahmed W, Prosser J, Lettice L, Allan G, Mattei MG, Farrall M, Hill RE, Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region. Genomics. 1997 Jan 15;39(2):205-15
2*	J:296646 Hughes JJ, Alkhunaizi E, Kruszka P, Pyle LC, Grange DK, Berger SI, Payne KK, Masser-Frye D, Hu T, Christie MR, Clegg NJ, Everson JL, Martinez AF, Walsh LE, Bedoukian E, Jones MC, Harris CJ, Riedhammer KM, Choukair D, Fechner PY, Rutter MM, Hufnagel SB, Roifman M, Kletter GB, Delot E, Vilain E, Lipinski RJ, Vezina CM, Muenke M, Chitayat D, Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations. Am J Hum Genet. 2020 Jan 2;106(1):121-128
5*	J:4086 Hui CC, Joyner AL, A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet. 1993 Mar;3(3):241-6
25*	J:17485 Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL, Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13
2*	J:316184 Hussein MT, Attaai A, Kamel G, Mokhtar DM, Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons. Gene Expr Patterns. 2021 Dec;42:119217
1	J:310417 Hwang SH, Somatilaka BN, White K, Mukhopadhyay S, Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner. Elife. 2021 Aug 4;10:e67121
1	J:41861 Hynes M, Stone DM, Dowd M, Pitts-Meek S, Goddard A, Gurney A , Rosenthal A, Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron. 1997 Jul;19(1):15-26
1	J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33
1*	J:225747 Jayewickreme CD, Shivdasani RA, Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1. Dev Biol. 2015 Sep 1;405(1):21-32
1	J:232412 Jeon S, Seong RH, Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway. PLoS Genet. 2016 Mar;12(3):e1005915
2	J:255472 Jimenez-Caliani AJ, Pillich R, Yang W, Diaferia GR, Meda P, Crisa L, Cirulli V, alphaE-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation. Cell Rep. 2017 Aug 8;20(6):1295-1306
1*	J:193107 Jin C, Chen J, Meng Q, Carreira V, Tam NN, Geh E, Karyala S, Ho SM, Zhou X, Medvedovic M, Xia Y, Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Dev Biol. 2013 Feb 1;374(1):96-107
1	J:164807 Joo JH, Taxter TJ, Munguba GC, Kim YH, Dhaduvai K, Dunn NW, Degan WJ, Oh SP, Sugrue SP, Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis. Dev Biol. 2010 Sep 15;345(2):191-203
4	J:315774 Junker JP, Peterson KA, Nishi Y, Mao J, McMahon AP, van Oudenaarden A, A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. Dev Cell. 2014 Nov 24;31(4):448-60
2*	J:316191 Kasaai B, Gaumond MH, Moffatt P, Regulation of the bone-restricted IFITM-like (Bril) gene transcription by Sp and Gli family members and CpG methylation. J Biol Chem. 2013 May 10;288(19):13278-94
2*	J:200761 Kasberg AD, Brunskill EW, Steven Potter S, SP8 regulates signaling centers during craniofacial development. Dev Biol. 2013 Sep 15;381(2):312-23
1	J:184749 Keady BT, Samtani R, Tobita K, Tsuchya M, San Agustin JT, Follit JA, Jonassen JA, Subramanian R, Lo CW, Pazour GJ, IFT25 Links the Signal-Dependent Movement of Hedgehog Components to Intraflagellar Transport. Dev Cell. 2012 May 15;22(5):940-51
1*	J:160585 Kesper DA, Didt-Koziel L, Vortkamp A, Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26
1	J:268349 Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR, Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease. Nat Commun. 2018 Nov 2;9(1):4600
1	J:102853 Kim JH, Huang Z, Mo R, Gli3 null mice display glandular overgrowth of the developing stomach. Dev Dyn. 2005 Dec;234(4):984-91
1	J:168981 Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman RM, Hui CC, Rosenblum ND, Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor. J Neurosci. 2011 Feb 2;31(5):1825-36
1*	J:252112 Kim JJ, Jiwani T, Erwood S, Loree J, Rosenblum ND, Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Dev Dyn. 2018 Jan;247(1):156-169
3	J:291852 Kim Y, Lee J, Seppala M, Cobourne MT, Kim SH, Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration. Nat Commun. 2020 Apr 24;11(1):1994
2*	J:158583 Ko HW, Norman RX, Tran J, Fuller KP, Fukuda M, Eggenschwiler JT, Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
4	J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28
2	J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810
2	J:133905 Koyama E, Ochiai T, Rountree RB, Kingsley DM, Enomoto-Iwamoto M, Iwamoto M, Pacifici M, Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling. Ann N Y Acad Sci. 2007 Nov;1116:100-12
2	J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60
2	J:191495 Kucerova R, Dora N, Mort RL, Wallace K, Leiper LJ, Lowes C, Neves C, Walczysko P, Bruce F, Fowler PA, Rajnicek AM, McCaig CD, Zhao M, West JD, Collinson JM, Interaction between hedgehog signalling and PAX6 dosage mediates maintenance and regeneration of the corneal epithelium. Mol Vis. 2012;18:139-50
1	J:220996 La Sala G, Marazziti D, Di Pietro C, Golini E, Matteoni R, Tocchini-Valentini GP, Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor. FASEB J. 2015 May;29(5):2059-69
9	J:78990 Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol. 2002 Sep 15;249(2):349-66
2*	J:119875 Lebel M, Mo R, Shimamura K, Hui CC, Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
4	J:338829 Lee J, Kim Y, Ataliotis P, Kim HG, Kim DW, Bennett DC, Brown NA, Layman LC, Kim SH, Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development. Sci Rep. 2023 Jul 29;13(1):12309
2*	J:41684 Lee J, Platt KA, Censullo P, Ruiz i Altaba A, Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development. 1997 Jul;124(13):2537-52
1*	J:293624 Lee S, Sears MJ, Zhang Z, Li H, Salhab I, Krebs P, Xing Y, Nah HD, Williams T, Carstens RP, Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development. 2020 Apr 30;147(21):dev187369
1	J:92067 Lei Q, Zelman AK, Kuang E, Li S, Matise MP, Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord. Development. 2004 Aug;131(15):3593-604
5	J:182649 Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT, Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90
1	J:42408 Lewis MT, Ross S, Strickland PA, Sugnet CW, Jimenez E, Scott MP, Daniel CW, Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1. Development. 1999 Nov;126(22):5181-93
5	J:69771 Lewis PM, Dunn MP, McMahon JA, Logan M, Martin JF, St-Jacques B, McMahon AP, Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell. 2001 Jun 1;105(5):599-612
1	J:321504 Lex RK, Zhou W, Ji Z, Falkenstein KN, Schuler KE, Windsor KE, Kim JD, Ji H, Vokes SA, GLI transcriptional repression is inert prior to Hedgehog pathway activation. Nat Commun. 2022 Feb 10;13(1):808
4	J:222442 Li BI, Matteson PG, Ababon MF, Nato AQ Jr, Lin Y, Nanda V, Matise TC, Millonig JH, The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation. Dev Biol. 2015 Jun 1;402(1):17-31
2	J:245974 Li J, Cui Y, Xu J, Wang Q, Yang X, Li Y, Zhang X, Qiu M, Zhang Z, Zhang Z, Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development. J Biol Chem. 2017 Sep 22;292(38):15814-15825
1	J:169530 Li J, Wang C, Pan Y, Bai Z, Wang B, Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo. Dev Dyn. 2011 Apr;240(4):766-74
1*	J:248981 Li J, Wang C, Wu C, Cao T, Xu G, Meng Q, Wang B, PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant. Dev Biol. 2017 Sep 1;429(1):147-157
2	J:235489 Li J, Wang Q, Cui Y, Yang X, Li Y, Zhang X, Qiu M, Zhang Z, Zhang Z, Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin. PLoS One. 2015;10(5):e0128006
4	J:254469 Li J, Wang S, Anderson C, Zhao F, Qin Y, Wu D, Wu X, Liu J, He X, Zhao J, Zhang J, Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. PLoS One. 2016;11(8):e0159639
1	J:332136 Li X, Gordon PJ, Gaynes JA, Fuller AW, Ringuette R, Santiago CP, Wallace V, Blackshaw S, Li P, Levine EM, Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis. Elife. 2022 Dec 2;11
1	J:190509 Li Y, Hibbs MA, Gard AL, Shylo NA, Yun K, Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1. Stem Cells. 2012 Apr;30(4):741-52
1	J:151965 Liem KF Jr, He M, Ocbina PJ, Anderson KV, Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13377-82
1	J:106707 Lien WH, Klezovitch O, Fernandez TE, Delrow J, Vasioukhin V, alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway. Science. 2006 Mar 17;311(5767):1609-12
2*	J:76411 Lim L, Kalinichenko VV, Whitsett JA, Costa RH, Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele. Am J Physiol Lung Cell Mol Physiol. 2002 May;282(5):L1012-22
1	J:214993 Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT, Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15;392(2):324-33
1	J:181885 Liu C, Bakeri H, Li T, Swaroop A, Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet. 2012 Apr 15;21(8):1848-60
1	J:202355 Liu HX, Ermilov A, Grachtchouk M, Li L, Gumucio DL, Dlugosz AA, Mistretta CM, Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance. Dev Biol. 2013 Oct 1;382(1):82-97
2	J:221426 Liu J, Zeng H, Liu A, The loss of Hh responsiveness by a non-ciliary Gli2 variant. Development. 2015 May 1;142(9):1651-60
1	J:279065 Liu W, Han F, Qu S, Yao Y, Zhao J, Akhtar ML, Ci Y, Zhang H, Li H, Zhao Y, Yue L, Zhang Y, Wang C, Li Y, MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development. Cell Death Dis. 2018 Sep 24;9(10):999
1	J:259048 Liu X, Wang Y, Liu F, Zhang M, Song H, Zhou B, Lo CW, Tong S, Hu Z, Zhang Z, Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling. Sci Signal. 2018 Feb 27;11(519)
1	J:184012 Lopez-Rios J, Speziale D, Robay D, Scotti M, Osterwalder M, Nusspaumer G, Galli A, Hollander GA, Kmita M, Zeller R, GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. Dev Cell. 2012 Apr 17;22(4):837-48
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:228335 Makino S, Zhulyn O, Mo R, Puviindran V, Zhang X, Murata T, Fukumura R, Ishitsuka Y, Kotaki H, Matsumaru D, Ishii S, Hui CC, Gondo Y, T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor. PLoS One. 2015;10(3):e0119455
1	J:160363 Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP, Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development. 2010 May;137(10):1721-9
1	J:121301 Mau E, Whetstone H, Yu C, Hopyan S, Wunder JS, Alman BA, PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms. Dev Biol. 2007 May 1;305(1):28-39
3*	J:170258 Mavromatakis YE, Lin W, Metzakopian E, Ferri AL, Yan CH, Sasaki H, Whisett J, Ang SL, Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity. Mech Dev. 2011 Jan-Feb;128(1-2):90-103
4	J:95326 McDermott A, Gustafsson M, Elsam T, Hui CC, Emerson CP Jr, Borycki AG, Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation. Development. 2005 Jan;132(2):345-57
2	J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13;
1	J:212851 Meng Q, Jin C, Chen Y, Chen J, Medvedovic M, Xia Y, Expression of signaling components in embryonic eyelid epithelium. PLoS One. 2014;9(2):e87038
1	J:239291 Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL, Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. Development. 2015 Apr 01;142(7):1315-24
2	J:88344 Miao D, Liu H, Plut P, Niu M, Huo R, Goltzman D, Henderson JE, Impaired endochondral bone development and osteopenia in Gli2-deficient mice. Exp Cell Res. 2004 Mar 10;294(1):210-22
1	J:81295 Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC, Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev. 2003 Jan 15;17(2):282-94
2	J:30339 Millen KJ, Hui CC, Joyner AL, A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum. Development. 1995 Dec;121(12):3935-45
1	J:241005 Millington G, Elliott KH, Chang YT, Chang CF, Dlugosz A, Brugmann SA, Cilia-dependent GLI processing in neural crest cells is required for tongue development. Dev Biol. 2017 Apr 15;424(2):124-137
4*	J:38381 Mo R, Freer AM, Zinyk DL, Crackower MA, Michaud J, Heng HH, Chik KW, Shi XM, Tsui LC, Cheng SH, Joyner AL, Hui C, Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development. 1997 Jan;124(1):113-23
1	J:70870 Mo R, Kim JH, Zhang J, Chiang C, Hui CC, Kim PC, Anorectal malformations caused by defects in sonic hedgehog signaling. Am J Pathol. 2001 Aug;159(2):765-74
1*	J:88577 Mu X, Beremand PD, Zhao S, Pershad R, Sun H, Scarpa A, Liang S, Thomas TL, Klein WH, Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Development. 2004 Mar;131(6):1197-210
3	J:193395 Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, Jackson PK, The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 2013 Jan 17;152(1-2):210-23
1	J:309437 Nakagawa N, Li J, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES, APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017 Aug 15;31(16):1679-1692
2*	J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062
3*	J:80052 Nakashima M, Tanese N, Ito M, Auerbach W, Bai C, Furukawa T, Toyono T, Akamine A, Joyner AL, A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development. Mech Dev. 2002 Nov;119(1):21
3	J:273907 Nandadasa S, Kraft CM, Wang LW, O'Donnell A, Patel R, Gee HY, Grobe K, Cox TC, Hildebrandt F, Apte SS, Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis. Nat Commun. 2019 Feb 27;10(1):953
1	J:229930 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G, The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5:e09584
2	J:65651 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev. 2000 Nov;98(1-2):77-94
1	J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44
1	J:97323 Niedermaier M, Schwabe GC, Fees S, Helmrich A, Brieske N, Seemann P, Hecht J, Seitz V, Stricker S, Leschik G, Schrock E, Selby PB, Mundlos S, An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression. J Clin Invest. 2005 Apr 1;115(4):900-909
3	J:147574 Norman RX, Ko HW, Huang V, Eun CM, Abler LL, Zhang Z, Sun X, Eggenschwiler JT, Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Hum Mol Genet. 2009 May 15;18(10):1740-54
2	J:220963 Nosavanh L, Yu DH, Jaehnig EJ, Tong Q, Shen L, Chen MH, Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5069-74
1	J:278935 Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA, Charalambous M, Clark AJL, Chan LF, MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. FASEB J. 2018 Jun 7;:fj201701274RR
4	J:78407 O'Rourke MP, Soo K, Behringer RR, Hui CC, Tam PP, Twist plays an essential role in FGF and SHH signal transduction during mouse limb development. Dev Biol. 2002 Aug 1;248(1):143-56
1	J:188764 Ocbina PJ, Eggenschwiler JT, Moskowitz I, Anderson KV, Complex interactions between genes controlling trafficking in primary cilia. Nat Genet. 2011 Jun;43(6):547-53
1	J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092
3*	J:64180 Outram SV, Varas A, Pepicelli CV, Crompton T, Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity. 2000 Aug;13(2):187-97
1*	J:90384 Palma V, Ruiz i Altaba A, Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex. Development. 2004 Jan;131(2):337-45
1	J:96926 Pan L, Yang Z, Feng L, Gan L, Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis. Development. 2005 Feb;132(4):703-12
2	J:108433 Pan Y, Bai CB, Joyner AL, Wang B, Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation. Mol Cell Biol. 2006 May;26(9):3365-77
2*	J:60986 Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL, Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development. 2000 Apr;127(8):1593-605
1	J:147584 Patterson VL, Damrau C, Paudyal A, Reeve B, Grimes DT, Stewart ME, Williams DJ, Siggers P, Greenfield A, Murdoch JN, Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway. Hum Mol Genet. 2009 May 15;18(10):1719-39
3*	J:153731 Pazin DE, Albrecht KH, Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov;238(11):2877-90
2	J:50051 Pepicelli CV, Lewis PM, McMahon AP, Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol. 1998 Sep 24;8(19):1083-6
1	J:234178 Perdigoto CN, Dauber KL, Bar C, Tsai PC, Valdes VJ, Cohen I, Santoriello FJ, Zhao D, Zheng D, Hsu YC, Ezhkova E, Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016 Jul;12(7):e1006151
2*	J:40587 Persengiev SP, Kondova II, Millette CF, Kilpatrick DL, Gli family members are differentially expressed during the mitotic phase of spermatogenesis. Oncogene. 1997 May 15;14(19):2259-64
5	J:316612 Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP, Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev. 2012 Dec 15;26(24):2802-16
2*	J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302
3	J:168317 Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT, Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1456-61
3	J:335097 Qin T, Ho CC, Wang B, Hui CC, Sham MH, Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206571119
2	J:238372 Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM, A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. Cell Rep. 2016 Jun 28;16(1):66-78
1	J:202828 Regard JB, Malhotra D, Gvozdenovic-Jeremic J, Josey M, Chen M, Weinstein LS, Lu J, Shore EM, Kaplan FS, Yang Y, Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification. Nat Med. 2013 Nov;19(11):1505-12
2	J:185828 Ren Y, Cowan RG, Migone FF, Quirk SM, Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice. Biol Reprod. 2012 Jun;86(6):174
2*	J:160812 Ribes V, Balaskas N, Sasai N, Cruz C, Dessaud E, Cayuso J, Tozer S, Yang LL, Novitch B, Marti E, Briscoe J, Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev. 2010 Jun 1;24(11):1186-200
2	J:144016 Ribes V, Le Roux I, Rhinn M, Schuhbaur B, Dolle P, Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways. Development. 2009 Feb;136(4):665-76
2*	J:104154 Rice R, Connor E, Rice DP, Expression patterns of Hedgehog signalling pathway members during mouse palate development. Gene Expr Patterns. 2006 Jan;6(2):206-12
1	J:178379 Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, Le Grand F, Sgarioto N, Guernec A, Schmitt A, Cagnard N, Huang R, Legay C, Guillet-Deniau I, Maire P, Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20
10	J:171486 Rutter M, Wang J, Huang Z, Kuliszewski M, Post M, Gli2 influences proliferation in the developing lung through regulation of cyclin expression. Am J Respir Cell Mol Biol. 2010 May;42(5):615-25
2	J:306807 Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S, Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ. iScience. 2020 Jul 24;23(7):101329
1	J:95234 Saitsu H, Komada M, Suzuki M, Nakayama R, Motoyama J, Shiota K, Ishibashi M, Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain. Dev Dyn. 2005 Feb;232(2):282-92
1	J:149518 Sakagami K, Gan L, Yang XJ, Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina. J Neurosci. 2009 May 27;29(21):6932-44
3	J:205383 Salti A, Nat R, Neto S, Puschban Z, Wenning G, Dechant G, Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons. Stem Cells Dev. 2013 Feb 1;22(3):397-411
1	J:143442 Sanchez-Camacho C, Bovolenta P, Autonomous and non-autonomous Shh signalling mediate the in vivo growth and guidance of mouse retinal ganglion cell axons. Development. 2008 Nov;135(21):3531-41
1	J:266826 Sandberg M, Flandin P, Silberberg S, Su-Feher L, Price JD, Hu JS, Kim C, Visel A, Nord AS, Rubenstein JLR, Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons. Neuron. 2016 Sep 21;91(6):1260-1275
2*	J:40390 Sasaki H, Hui C, Nakafuku M, Kondoh H, A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development. 1997 Apr;124(7):1313-22
3*	J:152817 Sehgal R, Sheibani N, Rhodes SJ, Belecky Adams TL, BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression. Dev Biol. 2009 Aug 15;332(2):429-43
1*	J:117221 Shibukawa Y, Young B, Wu C, Yamada S, Long F, Pacifici M, Koyama E, Temporomandibular joint formation and condyle growth require Indian hedgehog signaling. Dev Dyn. 2007 Feb;236(2):426-34
1	J:270726 Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S, Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis. Cell Rep. 2018 Jan 30;22(5):1169-1184
2	J:276848 Shimada IS, Somatilaka BN, Hwang SH, Anderson AG, Shelton JM, Rajaram V, Konopka G, Mukhopadhyay S, Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities. Dev Biol. 2019 Jun 1;450(1):47-62
3*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1*	J:135151 Sigulinsky CL, Green ES, Clark AM, Levine EM, Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina. Dev Biol. 2008 May 15;317(2):560-75
1	J:243907 Snouffer A, Brown D, Lee H, Walsh J, Lupu F, Norman R, Lechtreck K, Ko HW, Eggenschwiler J, Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice. PLoS Genet. 2017 Aug;13(8):e1006912
1	J:243893 Solanki A, Lau CI, Saldana JI, Ross S, Crompton T, The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh. J Exp Med. 2017 Jul 03;214(7):2041-2058
2	J:297055 Somatilaka BN, Hwang SH, Palicharla VR, White KA, Badgandi H, Shelton JM, Mukhopadhyay S, Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling. Dev Cell. 2020 Sep 28;54(6):710-726.e8
2	J:50050 St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP, Sonic hedgehog signaling is essential for hair development. Curr Biol. 1998 Sep 24;8(19):1058-68
1	J:169133 Stafford DA, Brunet LJ, Khokha MK, Economides AN, Harland RM, Cooperative activity of noggin and gremlin 1 in axial skeleton development. Development. 2011 Mar;138(5):1005-14
1	J:155216 Stone DM, Murone M, Luoh S, Ye W, Armanini MP, Gurney A, Phillips H, Brush J, Goddard A, de Sauvage FJ, Rosenthal A, Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci. 1999 Dec;112(Pt 23):4437-48
1	J:325356 Su-Feher L, Rubin AN, Silberberg SN, Catta-Preta R, Lim KJ, Ypsilanti AR, Zdilar I, McGinnis CS, McKinsey GL, Rubino TE Jr, Hawrylycz MJ, Thompson C, Gartner ZJ, Puelles L, Zeng H, Rubenstein JLR, Nord AS, Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2108760119
1	J:105832 Svard J, Henricson KH, Persson-Lek M, Rozell B, Lauth M, Bergstrom A, Ericson J, Toftgard R, Teglund S, Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway. Dev Cell. 2006 Feb;10(2):187-97
6*	J:113421 Szczepny A, Hime GR, Loveland KL, Expression of hedgehog signalling components in adult mouse testis. Dev Dyn. 2006 Nov;235(11):3063-70
1*	J:147759 Tan M, Davis SW, Saunders TL, Zhu Y, Sun Y, RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6203-8
1	J:262053 Tan Z, Niu B, Tsang KY, Melhado IG, Ohba S, He X, Huang Y, Wang C, McMahon AP, Jauch R, Chan D, Zhang MQ, Cheah KSE, Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions. PLoS Genet. 2018 Apr;14(4):e1007346
1	J:270543 Tanahashi H, Suzuki T, Deletion of Lrp4 increases the incidence of microphthalmia. Biochem Biophys Res Commun. 2018 Nov 30;506(3):478-484
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
4	J:199133 Tang M, Luo SX, Tang V, Huang EJ, Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development. Neural Dev. 2013;8:8
1*	J:186504 Tanimoto Y, Veistinen L, Alakurtti K, Takatalo M, Rice DP, Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2). J Biol Chem. 2012 Jun 15;287(25):21429-38
2	J:353308 Teng X, He H, Yu H, Zhang X, Xing J, Shen J, Li C, Wang M, Shao L, Wang Z, Yang H, Zhang Y, Wu Q, LncRNAs in the Dlk1-Dio3 Domain Are Essential for Mid-Embryonic Heart Development. Int J Mol Sci. 2024 Jul 26;25(15)
1	J:241596 Tian H, Feng J, Li J, Ho TV, Yuan Y, Liu Y, Brindopke F, Figueiredo JC, Magee W 3rd, Sanchez-Lara PA, Chai Y, Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate. Hum Mol Genet. 2017 Mar 01;26(5):860-872
1	J:308686 Tiu GC, Kerr CH, Forester CM, Krishnarao PS, Rosenblatt HD, Raj N, Lantz TC, Zhulyn O, Bowen ME, Shokat L, Attardi LD, Ruggero D, Barna M, A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies. Dev Cell. 2021 Jul 26;56(14):2089-2102.e11
3	J:309653 Tong Y, Park SH, Wu D, Xu W, Guillot SJ, Jin L, Li X, Wang Y, Lin CS, Fu Z, An essential role of intestinal cell kinase in lung development is linked to the perinatal lethality of human ECO syndrome. FEBS Lett. 2017 May;591(9):1247-1257
1*	J:55583 Tribioli C, Lufkin T, The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen. Development. 1999 Dec;126(24):5699-711
4	J:181006 Tuson M, He M, Anderson KV, Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube. Development. 2011 Nov;138(22):4921-30
1	J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63
3	J:309718 Veistinen LK, Mustonen T, Hasan MR, Takatalo M, Kobayashi Y, Kesper DA, Vortkamp A, Rice DP, Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets. Front Physiol. 2017;8:1036
1*	J:216502 Wainwright EN, Svingen T, Ng ET, Wicking C, Koopman P, Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice. Dev Biol. 2014 Nov 15;395(2):342-54
1*	J:178818 Wang B, Harrison W, Overbeek PA, Zheng H, Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct;138(20):4487-97
2	J:298139 Wang C, Chang JY, Yang C, Huang Y, Liu J, You P, McKeehan WL, Wang F, Li X, Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis. J Biol Chem. 2013 Jul 26;288(30):22174-83
1	J:249241 Wang C, Li J, Meng Q, Wang B, Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse. Dev Biol. 2017 Oct 1;430(1):156-165
2*	J:260445 Wang C, Li J, Takemaru KI, Jiang X, Xu G, Wang B, Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse. Development. 2018 Mar 15;145(6):dev164236
1	J:161408 Wang C, Pan Y, Wang B, Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development. 2010 Jun;137(12):2001-9
2	J:215769 Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF, Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. J Clin Invest. 2014 Sep 2;124(9):3767-80
1*	J:308819 Wang H, Yang C, Li Y, Zhao S, Ma P, Mao B, RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6. Biochem Biophys Res Commun. 2021 Jun 11;557:323-328
1	J:112545 Wang XP, Aberg T, James MJ, Levanon D, Groner Y, Thesleff I, Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth. J Dent Res. 2005 Feb;84(2):138-43
1*	J:149309 Ward RJ, Lee L, Graham K, Satkunendran T, Yoshikawa K, Ling E, Harper L, Austin R, Nieuwenhuis E, Clarke ID, Hui CC, Dirks PB, Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma. Cancer Res. 2009 Jun 1;69(11):4682-90
1	J:295894 Wei G, Gao N, Chen J, Fan L, Zeng Z, Gao G, Li L, Fang G, Hu K, Pang X, Fan HY, Clevers H, Liu M, Zhang X, Li D, Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation. Development. 2020 Sep 2;147(17):dev185678
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1	J:325905 Willnow D, Benary U, Margineanu A, Vignola ML, Konrath F, Pongrac IM, Karimaddini Z, Vigilante A, Wolf J, Spagnoli FM, Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche. Nature. 2021 Sep;597(7874):87-91
1	J:242833 Wu C, Li J, Peterson A, Tao K, Wang B, Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse. Hum Mol Genet. 2017 Jul 01;26(13):2386-2397
1*	J:203805 Wu SP, Dong XR, Regan JN, Su C, Majesky MW, Tbx18 regulates development of the epicardium and coronary vessels. Dev Biol. 2013 Nov 15;383(2):307-20
1	J:251890 Xiao X, Tang JJ, Peng C, Wang Y, Fu L, Qiu ZP, Xiong Y, Yang LF, Cui HW, He XL, Yin L, Qi W, Wong CC, Zhao Y, Li BL, Qiu WW, Song BL, Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling. Mol Cell. 2017 Apr 6;66(1):154-162.e10
1	J:240543 Xin D, Christopher KJ, Zeng L, Kong Y, Weatherbee SD, IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture. Development. 2017 Apr 15;144(8):1544-1553
1*	J:267206 Xu S, Liu Y, Meng Q, Wang B, Rab34 small GTPase is required for Hedgehog signaling and an early step of ciliary vesicle formation in mouse. J Cell Sci. 2018 Nov 8;131(21):jcs213710
2	J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34
1	J:335806 Yan L, Yin H, Mi Y, Wu Y, Zheng Y, Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos. Front Cell Dev Biol. 2023;11:1084245
1	J:325725 Yang G, Lu S, Jiang J, Weng J, Zeng X, Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway. Int J Mol Sci. 2022 May 27;23(11)
1	J:119916 Yang HS, Hinds PW, pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development. BMC Dev Biol. 2007;7:6
1	J:347414 Yang J, Zhu L, Pan H, Ueharu H, Toda M, Yang Q, Hallett SA, Olson LE, Mishina Y, A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis. J Clin Invest. 2024 Mar 11;134(8)
1*	J:49653 Yang Y, Guillot P, Boyd Y, Lyon MF, McMahon AP, Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development. 1998 Aug;125(16):3123-32
6	J:321577 Yin W, Liontos A, Koepke J, Ghoul M, Mazzocchi L, Liu X, Lu C, Wu H, Fysikopoulos A, Sountoulidis A, Seeger W, Ruppert C, Gunther A, Stainier DYR, Samakovlis C, An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea. Development. 2022 Feb 1;149(3):dev199804
2*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1	J:298652 Yoshida S, Aoki K, Fujiwara K, Nakakura T, Kawamura A, Yamada K, Ono M, Yogosawa S, Yoshida K, The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis. Elife. 2020 Aug 6;9:e57381
1	J:352471 Yoshida S, Tsuneoka Y, Tsukada T, Nakakura T, Kawamura A, Kai W, Yoshida K, Primary Cilia are Required for Cell-Type Determination and Angiogenesis in Pituitary Development. Endocrinology. 2024 Jul 1;165(8)
1	J:194893 Yu K, McGlynn S, Matise MP, Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord. Development. 2013 Apr;140(7):1594-604
1	J:153550 Yu W, Wang Y, McDonnell K, Stephen D, Bai CB, Patterning of ventral telencephalon requires positive function of Gli transcription factors. Dev Biol. 2009 Oct 1;334(1):264-75
1	J:280702 Yung T, Poon F, Liang M, Coquenlorge S, McGaugh EC, Hui CC, Wilson MD, Nostro MC, Kim TH, Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019 Oct 11;10(1):4647
1	J:352479 Zeng H, Ali S, Sebastian A, Ramos-Medero AS, Albert I, Dean C, Liu A, CPLANE protein INTU regulates growth and patterning of the mouse lungs through cilia-dependent Hh signaling. Dev Biol. 2024 Jul 17;515:92-101
4	J:339247 Zhang C, Li Y, Cao J, Yu B, Zhang K, Li K, Xu X, Guo Z, Liang Y, Yang X, Yang Z, Sun Y, Kaartinen V, Ding K, Wang J, Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation. Open Biol. 2021 Jun;11(6):210020
1	J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510
1	J:328469 Zhang J, Zhou Y, Guo J, Li L, Liu H, Lu C, Jiang Y, Cui S, MicroRNA-7a2 is Required for the Development of Pituitary Stem Cells. Stem Cells Dev. 2022 Jul;31(13-14):357-368
4	J:97242 Zhang XQ, Afink GB, Hu XR, Nister M, Forsberg-Nilsson K, Gli1 is not required for Pdgfralpha expression during mouse embryonic development. Differentiation. 2005 Mar;73(2-3):109-19
2	J:177881 Zhang Z, Wlodarczyk BJ, Niederreither K, Venugopalan S, Florez S, Finnell RH, Amendt BA, Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One. 2011;6(9):e24608
1	J:150793 Zhou S, Degan S, Potts EN, Foster WM, Sunday ME, NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11691-6
5	J:219584 Zhulyn O, Hui CC, Sufu and Kif7 in limb patterning and development. Dev Dyn. 2015 Mar;244(3):468-78
2	J:213417 Zhulyn O, Li D, Deimling S, Vakili NA, Mo R, Puviindran V, Chen MH, Chuang PT, Hopyan S, Hui CC, A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers. Dev Cell. 2014 Apr 28;29(2):241-9
1*	J:218166 Zhulyn O, Nieuwenhuis E, Liu YC, Angers S, Hui CC, Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development. Dev Biol. 2015 Jan 15;397(2):191-202
4*	J:70832 Zulch A, Becker MB, Gruss P, Expression pattern of Irx1 and Irx2 during mouse digit development. Mech Dev. 2001 Aug;106(1-2):159-62