Gene Expression Literature Summary

• Symbol: Gnai2
• Name: G protein subunit alpha i2
• ID: MGI:95772

31 matching records from 31 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3.5	E4	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)								1									6
In situ RNA (section)							2	5		2	2		2	1			12
Immunohistochemistry (whole mount)	1	1										1		1			2
In situ RNA (whole mount)									1
Northern blot	1	1		1		1									1		2
Western blot																	1
RT-PCR	1	1	1		1			2				2					6
cDNA clones																1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gnai2  G protein subunit alpha i2   (Synonyms: Galphai2, Gia, Gnai-2)
Results	Reference
1	J:187456 Berghard A, Hagglund AC, Bohm S, Carlsson L, Lhx2-dependent specification of olfactory sensory neurons is required for successful integration of olfactory, vomeronasal, and GnRH neurons. FASEB J. 2012 Aug;26(8):3464-72
4*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1	J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55
2	J:75436 Cloutier JF, Giger RJ, Koentges G, Dulac C, Kolodkin AL, Ginty DD, Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons. Neuron. 2002 Mar 14;33(6):877-92
1*	J:215434 Dietschi Q, Assens A, Challet L, Carleton A, Rodriguez I, Convergence of FPR-rs3-expressing neurons in the mouse accessory olfactory bulb. Mol Cell Neurosci. 2013 Sep;56:140-7
1*	J:331962 Dietschi Q, Tuberosa J, Fodoulian L, Boillat M, Kan C, Codourey J, Pauli V, Feinstein P, Carleton A, Rodriguez I, Clustering of vomeronasal receptor genes is required for transcriptional stability but not for choice. Sci Adv. 2022 Nov 18;8(46):eabn7450
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4	J:174520 Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 Controls the Differentiation of Vomeronasal Sensory Neurons in Mice. J Neurosci. 2011 Jul 13;31(28):10159-10173
2	J:110621 Fleischer J, Schwarzenbacher K, Besser S, Hass N, Breer H, Olfactory receptors and signalling elements in the Grueneberg ganglion. J Neurochem. 2006 Jul;98(2):543-54
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:238431 Hamada N, Negishi Y, Mizuno M, Miya F, Hattori A, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Tabata H, Saitoh S, Nagata KI, Role of a heterotrimeric G-protein, Gi2, in the corticogenesis: possible involvement in periventricular nodular heterotopia and intellectual disability. J Neurochem. 2017 Jan;140(1):82-95
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
2*	J:152814 Hornberg M, Gussing F, Berghard A, Bohm S, Retinoic acid selectively inhibits death of basal vomeronasal neurons during late stage of neural circuit formation. J Neurochem. 2009 Aug;110(4):1263-75
3	J:338698 Jarysta A, Tadenev ALD, Day M, Krawchuk B, Low BE, Wiles MV, Tarchini B, Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis. Elife. 2024 Apr 23;12
1	J:242405 Kask K, Ruisu K, Tikker L, Karis K, Saare M, Meier R, Karis A, Tonissoo T, Pooga M, Deletion of RIC8A in neural precursor cells leads to altered neurogenesis and neonatal lethality of mouse. Dev Neurobiol. 2015 Sep;75(9):984-1002
1	J:67679 Knoll B, Zarbalis K, Wurst W, Drescher U, A role for the EphA family in the topographic targeting of vomeronasal axons. Development. 2001 Mar;128(6):895-906
3	J:239974 Lacomme M, Tarchini B, Boudreau-Pinsonneault C, Monat C, Cayouette M, The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Development. 2016 Feb 15;143(4):575-81
1*	J:198109 Oeschger FM, Wang WZ, Lee S, Garcia-Moreno F, Goffinet AM, Arbones ML, Rakic S, Molnar Z, Gene expression analysis of the embryonic subplate. Cereb Cortex. 2012 Jun;22(6):1343-59
1	J:193170 Plummer NW, Spicher K, Malphurs J, Akiyama H, Abramowitz J, Nurnberg B, Birnbaumer L, Development of the mammalian axial skeleton requires signaling through the Galpha(i) subfamily of heterotrimeric G proteins. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21366-71
2	J:198564 Prince JE, Brignall AC, Cutforth T, Shen K, Cloutier JF, Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression. Development. 2013 Jun;140(11):2398-408
1	J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22
5	J:27182 Rambhatla L, Patel B, Dhanasekaran N, Latham KE, Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach. Mol Reprod Dev. 1995 Jul;41(3):314-24
3*	J:237701 Saare M, Lulla S, Tonissoo T, Meier R, Kask K, Ruisu K, Karis A, Salumets A, Pooga M, Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis. PLoS One. 2015;10(6):e0129131
4*	J:74178 Schuller U, Lamp EC, Schilling K, Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex. Histochem Cell Biol. 2001 Aug;116(2):149-59
2	J:48167 Suzuki Y, Shen T, Poyard M, Best-Belpomme M, Hanoune J, Defer N, Expression of adenylyl cyclase mRNAs in the denervated and in the developing mouse skeletal muscle. Am J Physiol. 1998 Jun;274(6 Pt 1):C1674-85
1	J:138609 Takatoh J, Kudoh H, Kondo S, Hanaoka K, Loss of short dystrophin isoform Dp71 in olfactory ensheathing cells causes vomeronasal nerve defasciculation in mouse olfactory system. Exp Neurol. 2008 Sep;213(1):36-47
1	J:214064 Tarchini B, Jolicoeur C, Cayouette M, A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. Dev Cell. 2013 Oct 14;27(1):88-102
1	J:172908 Traver S, Bidot C, Spassky N, Baltauss T, De Tand MF, Thomas JL, Zalc B, Janoueix-Lerosey I, Gunzburg JD, RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Biochem J. 2000 Aug 15;350 Pt 1:19-29
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
5*	J:34526 Williams CJ, Schultz RM, Kopf GS, G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23
3	J:126289 Zhao J, Izumi T, Nunomura K, Satoh S, Watanabe S, MARCKS-like protein, a membrane protein identified for its expression in developing neural retina, plays a role in regulating retinal cell proliferation. Biochem J. 2007 Nov 15;408(1):51-9