Gene Expression Literature Summary

• Symbol: Gnaq
• Name: guanine nucleotide binding protein, alpha q polypeptide
• ID: MGI:95776

17 matching records from 17 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3.5	E4	E8.5	E9.5	E11.5	E12.5	E13.5	E14.5	E15.5	E17.5	E18.5	E	P
Immunohistochemistry (section)																	1
In situ RNA (section)									1			2	1				1
In situ RNA (whole mount)										1
Northern blot	1	1		1		1											1
Western blot										1	2				1		4
RT-PCR	1	1	1		1		1	1				2	1	1	1		2
cDNA clones																1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gnaq  guanine nucleotide binding protein, alpha q polypeptide   (Synonyms: 1110005L02Rik, 6230401I02Rik, Dsk1, Dsk10, G alpha q, Galphaq, Gq, GqI)
Results	Reference
3	J:242531 Bedogni F, Cobolli Gigli C, Pozzi D, Rossi RL, Scaramuzza L, Rossetti G, Pagani M, Kilstrup-Nielsen C, Matteoli M, Landsberger N, Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms. Cereb Cortex. 2016 Jun;26(6):2517-2529
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:104550 Dettlaff-Swiercz DA, Wettschureck N, Moers A, Huber K, Offermanns S, Characteristic defects in neural crest cell-specific Galphaq/Galpha11- and Galpha12/Galpha13-deficient mice. Dev Biol. 2005 Jun 1;282(1):174-82
1	J:77728 Gu JL, Muller S, Mancino V, Offermanns S, Simon MI, Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9352-7
1*	J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26
1	J:345823 Izquierdo-Villalba I, Mirra S, Manso Y, Parcerisas A, Rubio J, Del Valle J, Gil-Bea FJ, Ulloa F, Herrero-Lorenzo M, Verdaguer E, Beninca C, Castro-Torres RD, Rebollo E, Marfany G, Auladell C, Navarro X, Enriquez JA, Lopez de Munain A, Soriano E, Aragay AM, A mammalian-specific Alex3/Galpha(q) protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival. Sci Signal. 2024 Feb 6;17(822):eabq1007
1	J:316188 Lee MJ, Kim DE, Zakrzewska A, Yoo YD, Kim SH, Kim ST, Seo JW, Lee YS, Dorn GW 2nd, Oh U, Kim BY, Kwon YT, Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes. J Biol Chem. 2012 Jul 6;287(28):24043-52
2*	J:102474 Lee MJ, Tasaki T, Moroi K, An JY, Kimura S, Davydov IV, Kwon YT, RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15030-5
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:86589 McClive PJ, Hurley TM, Sarraj MA, van den Bergen JA, Sinclair AH, Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad. Genesis. 2003 Oct;37(2):84-90
1	J:50566 Offermanns S, Mancino V, Revel JP, Simon MI, Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science. 1997 Jan 24;275(5299):533-6
2*	J:49140 Offermanns S, Zhao LP, Gohla A, Sarosi I, Simon MI, Wilkie TM, Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice. EMBO J. 1998 Aug 3;17(15):4304-12
5	J:27182 Rambhatla L, Patel B, Dhanasekaran N, Latham KE, Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach. Mol Reprod Dev. 1995 Jul;41(3):314-24
4*	J:74178 Schuller U, Lamp EC, Schilling K, Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex. Histochem Cell Biol. 2001 Aug;116(2):149-59
1	J:172908 Traver S, Bidot C, Spassky N, Baltauss T, De Tand MF, Thomas JL, Zalc B, Janoueix-Lerosey I, Gunzburg JD, RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Biochem J. 2000 Aug 15;350 Pt 1:19-29
1	J:339551 Wetzel-Strong SE, Galeffi F, Benavides C, Patrucco M, Bullock JL, Gallione CJ, Lee HK, Marchuk DA, Developmental expression of the Sturge-Weber syndrome-associated genetic mutation in Gnaq: a formal test of Happle's paradominant inheritance hypothesis. Genetics. 2023 Aug 9;224(4)
5*	J:34526 Williams CJ, Schultz RM, Kopf GS, G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23