Gene Expression Literature Summary

• Symbol: Grb2
• Name: growth factor receptor bound protein 2
• ID: MGI:95805

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E8.5	E9.5	E10.5	E13.5	E15	E15.5	E16	E16.5	E17.5	E18.5	E	P
In situ RNA (section)			1						1	1		1	1
Immunohistochemistry (whole mount)	1
In situ RNA (whole mount)							1
Northern blot		1									1	1	1
Western blot			1	1						1		1	4
RT-PCR			1		1	1		1				1	2
cDNA clones			1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Grb2  growth factor receptor bound protein 2
Results	Reference
1*	J:74283 Chan R, Hardy WR, Laing MA, Hardy SE, Muller WJ, The Catalytic Activity of the ErbB-2 Receptor Tyrosine Kinase Is Essential for Embryonic Development. Mol Cell Biol. 2002 Feb;22(4):1073-8
3	J:288966 Chang S, Lu X, Wang S, Wang Z, Huo J, Huang J, Shangguan S, Li S, Zou J, Bao Y, Guo J, Wang F, Niu B, Zhang T, Qiu Z, Wu J, Wang L, The effect of folic acid deficiency on FGF pathway via Brachyury regulation in neural tube defects. FASEB J. 2019 Apr;33(4):4688-4702
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:97750 Jamora C, Lee P, Kocieniewski P, Azhar M, Hosokawa R, Chai Y, Fuchs E, A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol. 2005 Jan;3(1):e11
1	J:104361 Jiang ST, Chiou YY, Wang E, Lin HK, Lin YT, Chi YC, Wang CK, Tang MJ, Li H, Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of pkd1. Am J Pathol. 2006 Jan;168(1):205-20
2	J:272613 Koutelou E, Wang L, Schibler AC, Chao HP, Kuang X, Lin K, Lu Y, Shen J, Jeter CR, Salinger A, Wilson M, Chen YC, Atanassov BS, Tang DG, Dent SYR, USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037
2	J:233610 Peng Y, Lu Z, Li G, Piechowicz M, Anderson M, Uddin Y, Wu J, Qiu S, The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain. Mol Psychiatry. 2016 Jul;21(7):925-35
1*	J:66508 Sakai R, Henderson JT, O'Bryan JP, Elia AJ, Saxton TM, Pawson T, The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons. Neuron. 2000 Dec;28(3):819-33
1	J:69138 Saxton TM, Cheng AM, Ong SH, Lu Y, Sakai R, Cross JC, Pawson T, Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis. Curr Biol. 2001 May 1;11(9):662-70
2	J:35493 Stein E, Cerretti DP, Daniel TO, Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells. J Biol Chem. 1996 Sep 20;271(38):23588-93
9*	J:14183 Suen KL, Bustelo XR, Pawson T, Barbacid M, Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors. Mol Cell Biol. 1993 Sep;13(9):5500-12
1	J:98531 Xie Y, Wang Y, Sun T, Wang F, Trostinskaia A, Puscheck E, Rappolee DA, Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells. Mol Reprod Dev. 2005 May;71(1):1-11