Gene Expression Literature Summary

• Symbol: Htt
• Name: huntingtin
• ID: MGI:96067

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E12	E12.5	E14.5	E15	E16.5	E17	E18.5	P
Immunohistochemistry (section)					1				1			1	1	1		3
In situ RNA (section)	1	1	1	2						1	1					1
In situ RNA (whole mount)		2		2		1		1
Northern blot											1				1	1
Western blot							1		1			1		1		3
RT-PCR				1												2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Htt  huntingtin   (Synonyms: C430023I11Rik, HD, Hdh, htt, huntingtin, IT15)
Results	Reference
9	J:34936 Bhide PG, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young AB, Penney J, Golden J, Aronin N, DiFiglia M, Expression of normal and mutant huntingtin in the developing brain. J Neurosci. 1996 Sep 1;16(17):5523-35
1*	J:76174 Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR, Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. Hum Mol Genet. 2002 Apr 15;11(8):945-59
1*	J:90356 Dixon KT, Cearley JA, Hunter JM, Detloff PJ, Mouse Huntington's disease homolog mRNA levels: variation and allele effects. Gene Expr. 2004;11(5-6):221-31
4*	J:47784 Dragatsis I, Efstratiadis A, Zeitlin A, Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues. Development. 1998 Apr;125(8):1529-39
1*	J:27183 Duyao MP, Auerbach AB, Ryan A, Persichetti F, Barnes GT, McNeil SM, Ge P, Vonsattel JP, Gusella JF, Joyner AL, MacDonald ME, Inactivation of the mouse Huntington's disease gene homolog Hdh. Science. 1995 Jul 21;269(5222):407-10
1	J:309675 Elias S, Thion MS, Yu H, Sousa CM, Lasgi C, Morin X, Humbert S, Huntingtin regulates mammary stem cell division and differentiation. Stem Cell Reports. 2014 Apr 8;2(4):491-506
1	J:263646 Horiuchi K, Perez-Cerezales S, Papasaikas P, Ramos-Ibeas P, Lopez-Cardona AP, Laguna-Barraza R, Fonseca Balvis N, Pericuesta E, Fernandez-Gonzalez R, Planells B, Viera A, Suja JA, Ross PJ, Alen F, Orio L, Rodriguez de Fonseca F, Pintado B, Valcarcel J, Gutierrez-Adan A, Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice. Cell Rep. 2018 Apr 3;23(1):143-155
4*	J:41317 MacDonald ME, Duyao M, Calzonetti T, Auerbach A, Ryan A, Barnes G , White JK , Auerbach W , Vonsattel JP , Gusella JF , Joyner AL, Targeted inactivation of the mouse Huntington's disease gene homolog Hdh. Cold Spring Harb Symp Quant Biol. 1996;61:627-38
2*	J:274711 Niewiadomska-Cimicka A, Krzyzosiak A, Ye T, Podlesny-Drabiniok A, Dembele D, Dolle P, Krezel W, Genome-wide Analysis of RARbeta Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders. Mol Neurobiol. 2017 Jul;54(5):3859-3878
6*	J:26500 Schmitt I, Bachner D, Megow D, Henklein P, Hameister H, Epplen JT, Riess O, Expression of the Huntington disease gene in rodents: cloning the rat homologue and evidence for downregulation in non-neuronal tissues during development. Hum Mol Genet. 1995 Jul;4(7):1173-82
4	J:29267 Zeitlin S, Liu JP, Chapman DL, Papaioannou VE, Efstratiadis A, Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nat Genet. 1995 Oct;11(2):155-63
1	J:242134 Zhao Z, Cao L, Reece EA, Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4489-4494