Gene Expression Literature Summary

• Symbol: Hprt1
• Name: hypoxanthine phosphoribosyltransferase 1
• ID: MGI:96217

36 matching records from 36 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E3	E3.5	E4.5	E6.5	E7.5	E8.5	E9.5	E10.5	E11.5	E12.5	E13	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)																1			1		1		1
In situ RNA (section)									1				1				2	1					1
In situ RNA (whole mount)		1							1
In situ reporter (knock in)							1				1	1	1	1		1							1
Northern blot	1													1									1
Western blot												1				1			1		1		1
RT-PCR	2	1	1	1	1			2	4	3	6	4	1	6	1		2	2	3	1	1	1	8
Primer Extension						1			1														1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hprt1  hypoxanthine phosphoribosyltransferase 1   (Synonyms: Hprt)
Results	Reference
1	J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365
4	J:266054 Barratt KS, Diamand KEM, Arkell RM, Identification of reference genes suitable for RT-qPCR studies of murine gastrulation and patterning. Mamm Genome. 2018 Oct;29(9-10):656-662
2*	J:142334 Blewitt ME, Gendrel AV, Pang Z, Sparrow DB, Whitelaw N, Craig JM, Apedaile A, Hilton DJ, Dunwoodie SL, Brockdorff N, Kay GF, Whitelaw E, SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet. 2008 May;40(5):663-9
2*	J:35234 Carrel L, Hunt PA, Willard HF, Tissue and lineage-specific variation in inactive X chromosome expression of the murine Smcx gene. Hum Mol Genet. 1996 Sep;5(9):1361-6
8	J:31593 Cereghini S, Ott MO, Power S, Maury M, Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles. Development. 1992 Nov;116(3):783-97
2	J:148744 Chiba H, Hirasawa R, Kaneda M, Amakawa Y, Li E, Sado T, Sasaki H, De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes. Genesis. 2008 Dec;46(12):768-74
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:204566 Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N, Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
3*	J:324293 Gindi N, Grossman H, Bar-Joseph H, Miller I, Nemerovsky L, Hadas R, Nevo N, Galiani D, Dekel N, Shalgi R, Fyn and argonaute 2 participate in maternal-mRNA degradation during mouse oocyte maturation. Cell Cycle. 2022 Apr;21(8):792-804
1	J:267576 Gontan C, Mira-Bontenbal H, Magaraki A, Dupont C, Barakat TS, Rentmeester E, Demmers J, Gribnau J, REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in mice. Nat Commun. 2018 Nov 12;9(1):4752
5	J:308478 Haramoto Y, Sakata M, Kobayashi S, Visualization of X chromosome reactivation in mouse primordial germ cells in vivo. Biol Open. 2021 Apr 15;10(4):bio058602
1	J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6
1	J:173577 Hoki Y, Ikeda R, Mise N, Sakata Y, Ohhata T, Sasaki H, Abe K, Sado T, Incomplete X-inactivation initiated by a hypomorphic Xist allele in the mouse. Development. 2011 Jul;138(13):2649-59
2	J:142921 Hoki Y, Kimura N, Kanbayashi M, Amakawa Y, Ohhata T, Sasaki H, Sado T, A proximal conserved repeat in the Xist gene is essential as a genomic element for X-inactivation in mouse. Development. 2009 Jan;136(1):139-46
1	J:96358 Isono K, Mizutani-Koseki Y, Komori T, Schmidt-Zachmann MS, Koseki H, Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. Genes Dev. 2005 Mar 1;19(5):536-41
1	J:53312 Kaestner KH, Katz J, Liu Y, Drucker DJ, Schutz G, Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev. 1999 Feb 15;13(4):495-504
1	J:115851 Kalantry S, Magnuson T, The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation. PLoS Genet. 2006 May;2(5):e66
5	J:190424 Kraemer N, Neubert G, Issa L, Ninnemann O, Seiler AE, Kaindl AM, Reference genes in the developing murine brain and in differentiating embryonic stem cells. Neurol Res. 2012 Sep;34(7):664-8
3	J:157314 Ling KH, Hewitt CA, Beissbarth T, Hyde L, Banerjee K, Cheah PS, Cannon PZ, Hahn CN, Thomas PQ, Smyth GK, Tan SS, Thomas T, Scott HS, Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Genome Biol. 2009;10(10):R104
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:61969 Miyoshi N, Wagatsuma H, Wakana S, Shiroishi T, Nomura M, Aisaka K, Kohda T, Surani MA, Kaneko-Ishino T, Ishino F, Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q. Genes Cells. 2000 Mar;5(3):211-20
9	J:341495 Mizukoshi T, Yamada S, Sakakibara SI, Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development. eNeuro. 2023 Oct;10(10):ENEURO.0159-23.2023
2	J:176132 O'Leary J, Osborne LR, Global analysis of gene expression in the developing brain of gtf2ird1 knockout mice. PLoS One. 2011;6(8):e23868
1	J:25651 Perkins AC, Sharpe AH, Orkin SH, Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature. 1995 May 25;375(6529):318-22
1	J:243417 Sakata Y, Nagao K, Hoki Y, Sasaki H, Obuse C, Sado T, Defects in dosage compensation impact global gene regulation in the mouse trophoblast. Development. 2017 Aug 01;144(15):2784-2797
4	J:112954 Savarese F, Flahndorfer K, Jaenisch R, Busslinger M, Wutz A, Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Mol Cell Biol. 2006 Oct;26(19):7167-77
1*	J:208718 Selmi-Ruby S, Bouazza L, Obregon MJ, Conscience A, Flamant F, Samarut J, Borson-Chazot F, Rousset B, The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production. Endocrinology. 2014 Feb;155(2):635-46
1	J:80260 Son WY, Han CT, Lee JH, Jung KY, Lee HM, Choo YK, Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice. Dev Growth Differ. 2002 Jun;44(3):181-90
3	J:53707 Sturm K, Lafferty M, Tam PP, Pgk1 and Hprt gene activity in the peri-implantation mouse embryo is influenced by the parental origin of the X-chromosome. Int J Dev Biol. 1999 Jan;43(1):69-73
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
2	J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:40650 Wang Q, Latham KE, Requirement for protein synthesis during embryonic genome activation in mice. Mol Reprod Dev. 1997 Jul;47(3):265-70
1	J:346696 Wei C, Kesner B, Yin H, Lee JT, Imprinted X chromosome inactivation at the gamete-to-embryo transition. Mol Cell. 2024 Feb 29;
1	J:48502 Yagi H, Deguchi K, Aono A, Tani Y, Kishimoto T, Komori T, Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice. Blood. 1998 Jul 1;92(1):108-17
1	J:184585 Yamamoto M, Matsuzaki T, Takahashi R, Adachi E, Maeda Y, Yamaguchi S, Kitayama H, Echizenya M, Morioka Y, Alexander DB, Yagi T, Itohara S, Nakamura T, Akiyama H, Noda M, The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs. Biol Open. 2012;1(5):458-466