Gene Expression Literature Summary

• Symbol: Hspd1
• Name: heat shock protein 1 (chaperonin)
• ID: MGI:96242

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E18	E18.5	P
Immunohistochemistry (section)						1					1	1
In situ RNA (section)				2	1	4	1	2	1		2	2
Immunohistochemistry (whole mount)	1											2
In situ RNA (whole mount)			1		1
Northern blot						1
Western blot	1	1	2	3		2			1	1		6
RT-PCR			1	1		1						3
cDNA clones			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hspd1  heat shock protein 1 (chaperonin)   (Synonyms: Hsp60)
Results	Reference
1	J:303084 Alsina D, Lytovchenko O, Schab A, Atanassov I, Schober FA, Jiang M, Koolmeister C, Wedell A, Taylor RW, Wredenberg A, Larsson NG, FBXL4 deficiency increases mitochondrial removal by autophagy. EMBO Mol Med. 2020 Jul 7;12(7):e11659
1	J:316661 Barallobre MJ, Perier C, Bove J, Laguna A, Delabar JM, Vila M, Arbones ML, DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease. Cell Death Dis. 2014 Jun 12;5:e1289
3*	J:94934 Challen GA, Martinez G, Davis MJ, Taylor DF, Crowe M, Teasdale RD, Grimmond SM, Little MH, Identifying the molecular phenotype of renal progenitor cells. J Am Soc Nephrol. 2004 Sep;15(9):2344-57
1	J:282096 Duan Y, Wang H, Mitchell-Silbaugh K, Cai S, Fan F, Li Y, Tang H, Wang G, Fang X, Liu J, Jia N, Jing R, Ouyang K, Heat shock protein 60 regulates yolk sac erythropoiesis in mice. Cell Death Dis. 2019 Oct 10;10(10):766
1*	J:324216 Gross I, Brandt N, Vonk D, Koper F, Wohlbrand L, Rabus R, Witt M, Heep A, Plosch T, Hipp MS, Brauer AU, Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination. Front Cell Neurosci. 2022;16:797588
1	J:125325 Huang L, Min JN, Masters S, Mivechi NF, Moskophidis D, Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption. Genesis. 2007 Aug;45(8):487-501
1	J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23
1	J:230728 Kumar V, Bouameur JE, Bar J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Loffler-Wirth H, Seibel P, Magin TM, A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
3	J:253948 Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD, Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016 Aug;97:1-14
1	J:261809 Mayer C, Hafemeister C, Bandler RC, Machold R, Batista Brito R, Jaglin X, Allaway K, Butler A, Fishell G, Satija R, Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462
1	J:333724 Park EJ, Kim HS, Lee DH, Kim SM, Yoon JS, Lee JM, Im SJ, Lee H, Lee MW, Lee CW, Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation. Nat Commun. 2023 Feb 25;14(1):1097
1	J:342544 Radzishevsky I, Odeh M, Bodner O, Zubedat S, Shaulov L, Litvak M, Esaki K, Yoshikawa T, Agranovich B, Li WH, Radzishevsky A, Gottlieb E, Avital A, Wolosker H, Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2302780120
1	J:331835 Salazar-Petres E, Pereira-Carvalho D, Lopez-Tello J, Sferruzzi-Perri AN, Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice. Biol Reprod. 2022 Jun 13;106(6):1292-1311
3*	J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265
4	J:347601 Shen T, Wang S, Huang C, Zhu S, Zhu X, Li N, Wang H, Huang L, Ren M, Han Z, Ge J, Chen Z, Ouyang K, Cardiac-specific deletion of heat shock protein 60 induces mitochondrial stress and disrupts heart development in mice. Biochem Biophys Res Commun. 2024 May 28;710:149883
2	J:317438 Sheng X, Liu C, Yan G, Li G, Liu J, Yang Y, Li S, Li Z, Zhou J, Zhen X, Zhang Y, Diao Z, Hu Y, Fu C, Yao B, Li C, Cao Y, Lu B, Yang Z, Qin Y, Sun H, Ding L, The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals. EBioMedicine. 2021 Dec 30;75:103790
7*	J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33
3	J:277380 Telley L, Agirman G, Prados J, Amberg N, Fievre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D, Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 2019 May 10;364(6440)
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
4*	J:83730 Wang G, Zhang J, Moskophidis D, Mivechi NF, Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis. 2003 May;36(1):48-61
1	J:353791 Xu L, Tan C, Barr J, Talaba N, Verheyden J, Chin JS, Gaboyan S, Kasaraneni N, Elgamal RM, Gaulton KJ, Lin G, Afshar K, Golts E, Meier A, Alexander LEC, Borok Z, Shen Y, Chung WK, McCulley DJ, Sun X, Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells. Cell Stem Cell. 2024 Aug 16;
1	J:223428 Yamamoto M, Arimura H, Fukushige T, Minami K, Nishizawa Y, Tanimoto A, Kanekura T, Nakagawa M, Akiyama S, Furukawa T, Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation. Mol Cell Biol. 2014 Mar;34(6):1077-84
1	J:255262 Yu C, Fan X, Sha QQ, Wang HH, Li BT, Dai XX, Shen L, Liu J, Wang L, Liu K, Tang F, Fan HY, CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes. Cell Rep. 2017 Aug 1;20(5):1161-1172