Gene Expression Literature Summary

• Symbol: Hsp90aa1
• Name: heat shock protein 90, alpha (cytosolic), class A member 1
• ID: MGI:96250

32 matching records from 32 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E6.5	E7.5	E8	E8.5	E9	E9.5	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	E	P
Immunohistochemistry (section)		1	1	1	1	1	1	1		1		2		1		1		3		1				2	5
In situ RNA (section)			1		1			1	1			2	1	1	1	3	1		1	1	1		2		2
Northern blot														1
Western blot					1		1	1		1		1		2		1		1		2		1	2		6
RT-PCR	1						1	2			1							1							2
cDNA clones			2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hsp90aa1  heat shock protein 90, alpha (cytosolic), class A member 1   (Synonyms: hsp4, Hsp86-1, Hsp89, Hsp90, Hspca)
Results	Reference
1*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1	J:349721 Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosario M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC, Protein translation rate determines neocortical neuron fate. Nat Commun. 2024 Jun 7;15(1):4879
1	J:263707 Brown HM, Green ES, Tan TCY, Gonzalez MB, Rumbold AR, Hull ML, Norman RJ, Packer NH, Robertson SA, Thompson JG, Periconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaptation to pregnancy. Sci Rep. 2018 Feb 1;8(1):2114
2*	J:98076 Cai J, Ash D, Kotch LE, Jabs EW, Attie-Bitach T, Auge J, Mattei G, Etchevers H, Vekemans M, Korshunova Y, Tidwell R, Messina DN, Winston JB, Lovett M, Gene expression in pharyngeal arch 1 during human embryonic development. Hum Mol Genet. 2005 Apr 1;14(7):903-12
1*	J:277739 Chaves-Perez A, Yilmaz M, Perna C, de la Rosa S, Djouder N, URI is required to maintain intestinal architecture during ionizing radiation. Science. 2019 May 31;364(6443)
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:55460 Evrard L, Vanmuylder N, Dourov N, Glineur R, Louryan S, Cytochemical identification of HSP110 during early mouse facial development. J Craniofac Genet Dev Biol. 1999 Jan-Mar;19(1):24-32
1*	J:91051 Fiorenza MT, Bevilacqua A, Canterini S, Torcia S, Pontecorvi M, Mangia F, Early transcriptional activation of the hsp70.1 gene by osmotic stress in one-cell embryos of the mouse. Biol Reprod. 2004 Jun;70(6):1606-13
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:125325 Huang L, Min JN, Masters S, Mivechi NF, Moskophidis D, Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption. Genesis. 2007 Aug;45(8):487-501
5*	J:33469 Jaskoll T, Choy HA, Melnick M, The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-beta, and embryonic mouse lung development in vivo. Pediatr Res. 1996 May;39(5):749-59
1	J:50869 Ko MSH, Threat TA, Wang X, Horton JH, Cui Y, Pryor E, Paris J , Wells-Smith J , Kitchen JR , Rowe LB , Eppig J , Satoh T , Brant L , Fujiwara H , Yotsumoto S , Nakashima H, Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
1*	J:161796 Kumada T, Yamanaka Y, Kitano A, Shibata M, Awaya T, Kato T, Okawa K, Abe T, Oshima N, Nakahata T, Heike T, Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development. Dev Dyn. 2010 Aug;239(8):2233-45
1	J:329967 Li H, Li C, Zhai W, Zhang X, Li L, Wu B, Yu B, Zhang P, Li J, Cui CP, Zhang L, Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival. Cell Rep. 2022 Oct 4;41(1):111435
1*	J:52895 Loones MT, Morange M, Hsp and chaperone distribution during endochondral bone development in mouse embryo. Cell Stress Chaperones. 1998 Dec;3(4):237-44
2	J:126078 Merlet J, Racine C, Moreau E, Moreno SG, Habert R, Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3615-20
1	J:231873 Mohamed BA, Barakat AZ, Held T, Elkenani M, Muhlfeld C, Manner J, Adham IM, Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice. Am J Respir Cell Mol Biol. 2014 Apr;50(4):817-24
1	J:300057 Morishita H, Kanda Y, Kaizuka T, Chino H, Nakao K, Miki Y, Taketomi Y, Guan JL, Murakami M, Aiba A, Mizushima N, Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder. Cell Rep. 2020 Dec 8;33(10):108477
2	J:262221 Nakajima R, Okano H, Noce T, JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis. PLoS One. 2016;11(9):e0163466
1*	J:86720 Nayernia K, Vauti F, Meinhardt A, Cadenas C, Schweyer S, Meyer BI, Schwandt I, Chowdhury K, Engel W, Arnold HH, Inactivation of a testis-specific Lis1 transcript in mice prevents spermatid differentiation and causes male infertility. J Biol Chem. 2003 Nov 28;278(48):48377-85
1	J:301847 Ni L, Xie H, Tan L, Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models. Mol Reprod Dev. 2016 Dec;83(12):1060-1069
3	J:28424 Palis J, Kingsley PD, Differential gene expression during early murine yolk sac development. Mol Reprod Dev. 1995 Sep;42(1):19-27
1*	J:39331 Rallu M, Loones M, Lallemand Y, Morimoto R, Morange M, Mezger V, Function and regulation of heat shock factor 2 during mouse embryogenesis. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2392-7
1	J:185047 Sarkar AA, Zohn IE, Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme. J Cell Biol. 2012 Mar 19;196(6):789-800
3*	J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265
7*	J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33
14	J:80729 Vanmuylder N, Werry-Huet A, Rooze M, Louryan S, Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line. Anat Embryol (Berl). 2002 Jul;205(4):301-6
1*	J:58075 Voss AK, Thomas T, Gruss P, Mice lacking HSP90beta fail to develop a placental labyrinth. Development. 2000 Jan;127(1):1-11
8*	J:81589 Wada H, Kobayashi I, Yamaza H, Matsuo K, Kiyoshima T, Akhtar M, Sakai T, Koyano K, Sakai H, In situ expression of heat shock proteins, Hsc73, Hsj2 and Hsp86 in the developing tooth germ of mouse lower first molar. Histochem J. 2002 Mar-Apr;34(3-4):105-9
2	J:310647 Wang F, Wang Q, Liu B, Mei L, Ma S, Wang S, Wang R, Zhang Y, Niu C, Xiong Z, Zheng Y, Zhang Z, Shi J, Song X, The long noncoding RNA Synage regulates synapse stability and neuronal function in the cerebellum. Cell Death Differ. 2021 Sep;28(9):2634-2650
4*	J:83730 Wang G, Zhang J, Moskophidis D, Mivechi NF, Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis. 2003 May;36(1):48-61
2*	J:74152 Yamaza H, Matsuo K, Kiyoshima T, Shigemura N, Kobayashi I, Wada H, Akamime A, Sakai H, Detection of differentially expressed genes in the early developmental stage of the mouse mandible. Int J Dev Biol. 2001 Jun;45(4):675-80