Gene Expression Literature Summary

• Symbol: Il7r
• Name: interleukin 7 receptor
• ID: MGI:96562

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E9	E10.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	E	P
Immunohistochemistry (section)					3	5		1		5		2	3	1
In situ RNA (section)						1
Immunohistochemistry (whole mount)					1		1		1		1	3	1		1
RT-PCR	1	1	1	2		2	1		1		1	1		1	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Il7r  interleukin 7 receptor   (Synonyms: CD127, IL-7Ralpha, IL-7 receptor alpha chain)
Results	Reference
2	J:45633 Adachi S, Yoshida H, Honda K, Maki K, Saijo K, Ikuta K, Saito T, Nishikawa SI, Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlage. Int Immunol. 1998 Jan;10(1):1-6
2	J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30
1*	J:74716 DeKoter RP, Lee HJ, Singh H, PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors. Immunity. 2002 Feb;16(2):297-309
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:150211 Downes M, Francois M, Ferguson C, Parton RG, Koopman P, Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation. Hum Mol Genet. 2009 Aug 1;18(15):2839-50
1	J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73
2	J:82631 Fukuda K, Yoshida H, Sato T, Furumoto TA, Mizutani-Koseki Y, Suzuki Y, Saito Y, Takemori T, Kimura M, Sato H, Taniguchi M, Nishikawa S, Nakayama T, Koseki H, Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs. Dev Biol. 2003 Mar 15;255(2):278-89
1	J:124645 Itoi M, Tsukamoto N, Yoshida H, Amagai T, Mesenchymal cells are required for functional development of thymic epithelial cells. Int Immunol. 2007 Aug;19(8):953-64
4*	J:26827 Jia GQ, Gutierrez-Ramos JC, Analysis of interleukin receptor gene expression in mouse fetal liver by quantitative polymerase chain reaction. Eur J Immunol. 1995 Jul;25(7):2096-100
1	J:355331 Mao Y, Meng Y, Zou K, Qin N, Wang Y, Yan J, Chen P, Cheng Y, Shi W, Zhou C, Chen H, Sheng J, Liu X, Pan J, Huang H, Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance. J Neuroinflammation. 2024 Oct 4;21(1):249
1*	J:12563 McClanahan T, Dalrymple S, Barkett M, Lee F, Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells [see comments]. Blood. 1993 Jun 1;81(11):2903-15
3*	J:36693 Michaelson MD, Mehler MF, Xu H, Gross RE, Kessler JA, Interleukin-7 is trophic for embryonic neurons and is expressed in developing brain. Dev Biol. 1996 Oct 10;179(1):251-63
2	J:160065 Reijmers RM, Vondenhoff MF, Roozendaal R, Kuil A, Li JP, Spaargaren M, Pals ST, Mebius RE, Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase. J Immunol. 2010 Apr 1;184(7):3656-64
1*	J:187054 Roberts NA, White AJ, Jenkinson WE, Turchinovich G, Nakamura K, Withers DR, McConnell FM, Desanti GE, Benezech C, Parnell SM, Cunningham AF, Paolino M, Penninger JM, Simon AK, Nitta T, Ohigashi I, Takahama Y, Caamano JH, Hayday AC, Lane PJ, Jenkinson EJ,Anderson G, Rank signaling links the development of invariant gammadelta T cell progenitors and Aire(+) medullary epithelium. Immunity. 2012 Mar 23;36(3):427-37
2	J:112368 Sato T, Endoh M, Yoshida H, Yasuo S, Katsuno T, Saito Y, Isono K, Koseki H, Mammalian Polycomb complexes are required for Peyer's patch development by regulating lymphoid cell proliferation. Gene. 2006 Sep 1;379:166-74
4*	J:184087 Sugiyama M, Nakato G, Jinnohara T, Akiba H, Okumura K, Ohno H, Yoshida H, Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development. Int Immunol. 2012 Jun;24(6):369-78
1	J:208884 van de Pavert SA, Ferreira M, Domingues RG, Ribeiro H, Molenaar R, Moreira-Santos L, Almeida FF, Ibiza S, Barbosa I, Goverse G, Labao-Almeida C, Godinho-Silva C, Konijn T, Schooneman D, O'Toole T, Mizee MR, Habani Y, Haak E, Santori FR, Littman DR, Schulte-Merker S, Dzierzak E, Simas JP, Mebius RE, Veiga-Fernandes H, Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature. 2014 Apr 3;508(7494):123-7
2	J:157747 van de Pavert SA, Olivier BJ, Goverse G, Vondenhoff MF, Greuter M, Beke P, Kusser K, Hopken UE, Lipp M, Niederreither K, Blomhoff R, Sitnik K, Agace WW, Randall TD, de Jonge WJ, Mebius RE, Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol. 2009 Nov;10(11):1193-9
1	J:232386 Van Nguyen T, Angkasekwinai P, Dou H, Lin FM, Lu LS, Cheng J, Chin YE, Dong C, Yeh ET, SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. Mol Cell. 2012 Jan 27;45(2):210-21
3	J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61
3	J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45
2	J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34
1	J:81255 Yilmaz ZB, Weih DS, Sivakumar V, Weih F, RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J. 2003 Jan 2;22(1):121-30
2*	J:43157 Yoder MC, Hiatt K, Dutt P, Mukherjee P, Bodine DM, Orlic D, Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity. 1997 Sep;7(3):335-44
2	J:55393 Yoshida H, Honda K, Shinkura R, Adachi S, Nishikawa S, Maki K, Ikuta K, Nishikawa SI, IL-7 receptor alpha+ CD3(-) cells in the embryonic intestine induces the organizing center of Peyer's patches. Int Immunol. 1999 May;11(5):643-55