Gene Expression Literature Summary

• Symbol: Itgav
• Name: integrin alpha V
• ID: MGI:96608

40 matching records from 40 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E4	E6.5	E7.5	E8.5	E9	E9.5	E10.5	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)			1	1			3	2	2	1	2	1	3	2	3	4	1	2	1	1		6
In situ RNA (section)						1			1		2		3		3	1	1	1		1		2
In situ RNA (whole mount)					1		1
Northern blot													1						1			1
Western blot								2									1					4
RT-PCR	2	1		1		1					2		2		2	1					1	4
cDNA clones													1						1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Itgav  integrin alpha V   (Synonyms: 1110004F14Rik, 2610028E01Rik, alphav-integrin, CD51, D430040G12Rik, vitronectin receptor alpha polypeptide (VNRA))
Results	Reference
1	J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040
1	J:53260 Anton ES, Kreidberg JA, Rakic P, Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migration and laminar organization of the cerebral cortex. Neuron. 1999 Feb;22(2):277-89
1	J:94436 Barbour W, Saika S, Miyamoto T, Ohkawa K, Utsunomiya H, Ohnishi Y, Expression patterns of beta1-related alpha integrin subunits in murine lens during embryonic development and wound healing. Curr Eye Res. 2004 Jul;29(1):1-10
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
3	J:201077 Boisset JC, Clapes T, Van Der Linden R, Dzierzak E, Robin C, Integrin alphaIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol Open. 2013 May 15;2(5):525-32
5*	J:52558 Bowen JA, Hunt JS, Expression of cell adhesion molecules in murine placentas and a placental cell line. Biol Reprod. 1999 Feb;60(2):428-34
3	J:49179 Brancaccio M, Cabodi S, Belkin AM, Collo G, Koteliansky VE, Tomatis D, Altruda F, Silengo L, Tarone G, Differential onset of expression of alpha 7 and beta 1D integrins during mouse heart and skeletal muscle development. Cell Adhes Commun. 1998 Mar;5(3):193-205
1*	J:97068 Cachaco AS, Pereira CS, Pardal RG, Bajanca F, Thorsteinsdottir S, Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse. Dev Dyn. 2005 Apr;232(4):1069-78
2	J:195350 Chaen T, Konno T, Egashira M, Bai R, Nomura N, Nomura S, Hirota Y, Sakurai T, Imakawa K, Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. PLoS One. 2012;7(11):e48933
1	J:84858 Chan CS, Weeber EJ, Kurup S, Sweatt JD, Davis RL, Integrin requirement for hippocampal synaptic plasticity and spatial memory. J Neurosci. 2003 Aug 6;23(18):7107-16
1	J:153959 Conti FJ, Monkley SJ, Wood MR, Critchley DR, Muller U, Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions. Development. 2009 Nov;136(21):3597-606
1	J:171226 Cullen M, Elzarrad MK, Seaman S, Zudaire E, Stevens J, Yang MY, Li X, Chaudhary A, Xu L, Hilton MB, Logsdon D, Hsiao E, Stein EV, Cuttitta F, Haines DC, Nagashima K, Tessarollo L, St Croix B, GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5759-64
1*	J:321982 De A, Morales JE, Chen Z, Sebastian S, McCarty JH, The beta8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development. Development. 2022 Mar 15;149(6):dev200472
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:346073 Farhat B, Bordeu I, Jagla B, Ibrahim S, Stefanovic S, Blanc H, Loulier K, Simons BD, Beaurepaire E, Livet J, Puceat M, Understanding the cell fate and behavior of progenitors at the origin of the mouse cardiac mitral valve. Dev Cell. 2024 Feb 5;59(3):339-350.e4
1	J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89
2	J:176262 Giros A, Grgur K, Gossler A, Costell M, alpha5beta1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice. PLoS One. 2011;6(7):e22002
7	J:21014 Hirsch E, Gullberg D, Balzac F, Altruda F, Silengo L, Tarone G, Alpha v integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development. Dev Dyn. 1994 Oct;201(2):108-20
1	J:152840 Hou SC, Chan LW, Chou YC, Su CY, Chen X, Shih YL, Tsai PC, Shen CK, Yan YT, Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis. FEBS Lett. 2009 Sep 3;583(17):2765-71
1	J:167708 Jung Y, Kissil JL, McCarty JH, beta8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart. Dev Dyn. 2011 Jan;240(1):271-7
1	J:170286 Kitase Y, Yamashiro K, Fu K, Richman JM, Shuler CF, Spatiotemporal localization of periostin and its potential role in epithelial-mesenchymal transition during palatal fusion. Cells Tissues Organs. 2011;193(1-2):53-63
3	J:306330 Le D, Lim S, Min KW, Park JW, Kim Y, Ha T, Moon KH, Wagner KU, Kim JW, Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity. Mol Cells. 2021 Mar 31;44(3):168-178
1*	J:61486 Littlewood Evans A, Muller U, Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Nat Genet. 2000 Apr;24(4):424-8
1	J:145990 Liu J, He X, Corbett SA, Lowry SF, Graham AM, Fassler R, Li S, Integrins are required for the differentiation of visceral endoderm. J Cell Sci. 2009 Jan 15;122(Pt 2):233-42
1	J:306850 Lu T, Lin X, Pan YH, Yang N, Ye S, Zhang Q, Wang C, Zhu R, Zhang T, Wisniewski TM, Cao Z, Ding BS, Dang S, Zhang W, ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation. iScience. 2020 Aug 20;23(9):101472
1	J:178484 Maddala R, Chauhan BK, Walker C, Zheng Y, Robinson ML, Lang RA, Rao PV, Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011 Dec 1;360(1):30-43
2	J:94376 McCarty JH, Lacy-Hulbert A, Charest A, Bronson RT, Crowley D, Housman D, Savill J, Roes J, Hynes RO, Selective ablation of {alpha}v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death. Development. 2005 Jan;132(1):165-176
1	J:291494 Mole MA, Galea GL, Rolo A, Weberling A, Nychyk O, De Castro SC, Savery D, Fassler R, Ybot-Gonzalez P, Greene NDE, Copp AJ, Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure. Dev Cell. 2020 Feb 10;52(3):321-334.e6
2*	J:306186 Pisko J, Spirkova A, Cikos S, Olexikova L, Kovarikova V, Sefcikova Z, Fabian D, Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres. Sci Rep. 2021 Apr 29;11(1):9228
8*	J:31158 Salmivirta K, Gullberg D, Hirsch E, Altruda F, Ekblom P, Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. Dev Dyn. 1996 Feb;205(2):104-13
3*	J:152946 Sferruzzi-Perri AN, Macpherson AM, Roberts CT, Robertson SA, Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice. Biol Reprod. 2009 Jul;81(1):207-21
1	J:177399 Sorocos K, Kostoulias X, Cullen-McEwen L, Hart AH, Bertram JF, Caruana G, Expression patterns and roles of periostin during kidney and ureter development. J Urol. 2011 Oct;186(4):1537-44
1	J:53320 Stepp MA, Alpha9 and beta8 integrin expression correlates with the merger of the developing mouse eyelids. Dev Dyn. 1999 Mar;214(3):216-28
1	J:222261 Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D, Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos. Biol Open. 2015;4(5):596-607
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
11	J:31981 Wada J, Kumar A, Liu Z, Ruoslahti E, Reichardt L, Marvaldi J, Kanwar YS, Cloning of mouse integrin alphaV cDNA and role of the alphaV-related matrix receptors in metanephric development. J Cell Biol. 1996 Mar;132(6):1161-76
1*	J:70388 Weinstein M, Monga SP, Liu Y, Brodie SG, Tang Y, Li C, Mishra L, Deng CX, Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development. Mol Cell Biol. 2001 Aug;21(15):5122-31
1*	J:60748 Yang J, Boerm M, McCarty M, Bucana C, Fidler IJ, Zhuang Y, Su B, Mekk3 is essential for early embryonic cardiovascular development. Nat Genet. 2000 Mar;24(3):309-13
1*	J:36764 Yang JT, Hynes RO, Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins. Mol Biol Cell. 1996 Nov;7(11):1737-48
2	J:352471 Yoshida S, Tsuneoka Y, Tsukada T, Nakakura T, Kawamura A, Kai W, Yoshida K, Primary Cilia are Required for Cell-Type Determination and Angiogenesis in Pituitary Development. Endocrinology. 2024 Jul 1;165(8)