Gene Expression Literature Summary

• Symbol: Kcne1
• Name: potassium voltage-gated channel, Isk-related subfamily, member 1
• ID: MGI:96673

26 matching records from 26 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E19.5	P
Immunohistochemistry (section)										2		2						2
In situ RNA (section)						1		2			1							1
In situ RNA (whole mount)	1		2	2		1	1	1	1						1
In situ reporter (knock in)	1	1	2	2	1	2	1	2			1							3
Northern blot									1	1				1			1	2
RT-PCR	1		1	2		2	2	1	2	1			1	1	1	1		10
RNase protection																		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kcne1  potassium voltage-gated channel, Isk-related subfamily, member 1   (Synonyms: Isk, MinK, nmf190)
Results	Reference
2	J:156955 Alaynick WA, Way JM, Wilson SA, Benson WG, Pei L, Downes M, Yu R, Jonker JW, Holt JA, Rajpal DK, Li H, Stuart J, McPherson R, Remlinger KS, Chang CY, McDonnell DP, Evans RM, Billin AN, ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. Mol Endocrinol. 2010 Feb;24(2):299-309
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:225226 Dykes IM, van Bueren KL, Ashmore RJ, Floss T, Wurst W, Szumska D, Bhattacharya S, Scambler PJ, HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region. Circ Res. 2014 Jun 20;115(1):23-31
3*	J:20434 Felipe A, Knittle TJ, Doyle KL, Snyders DJ, Tamkun MM, Differential expression of Isk mRNAs in mouse tissue during development and pregnancy. Am J Physiol. 1994 Sep;267(3 Pt 1):C700-5
10*	J:74171 Franco D, Demolombe S, Kupershmidt S, Dumaine R, Dominguez JN, Roden D, Antzelevitch C, Escande D, Moorman AF, Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 2001 Oct;52(1):65-75
3*	J:80501 Gitton Y, Dahmane N, Baik S, Ruiz I Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML, A gene expression map of human chromosome 21 orthologues in the mouse. Nature. 2002 Dec 5;420(6915):586-90
1	J:355142 Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terren M, Benguria A, Simon-Chica A, Queiro-Palou A, Dopazo A, Sanchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Munoz-Canoves P, Redondo JM, The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun. 2024 Oct 4;15(1):8602
2*	J:119550 Harrell MD, Harbi S, Hoffman JF, Zavadil J, Coetzee WA, Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
1	J:224301 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV, MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol. 2015 Feb;35(4):649-61
3	J:89216 Jay PY, Harris BS, Maguire CT, Buerger A, Wakimoto H, Tanaka M, Kupershmidt S, Roden DM, Schultheiss TM, O'Brien TX, Gourdie RG, Berul CI, Izumo S, Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system. J Clin Invest. 2004 Apr;113(8):1130-7
3	J:108906 Koay G, Heffner R, Heffner H, Behavioral audiograms of homozygous med(J) mutant mice with sodium channel deficiency and unaffected controls. Hear Res. 2002 Sep;171(1-2):111-118
8*	J:84141 Kondo RP, Anderson RH, Kupershmidt S, Roden DM, Evans SM, Development of the cardiac conduction system as delineated by minK-lacZ. J Cardiovasc Electrophysiol. 2003 Apr;14(4):383-91
6*	J:2710 Lesage F, Attali B, Lazdunski M, Barhanin J, Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells. FEBS Lett. 1992 Sep 28;310(2):162-6
2*	J:91511 Mai W, Janier MF, Allioli N, Quignodon L, Chuzel T, Flamant F, Samarut J, Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10332-7
1	J:237617 Menendez-Montes I, Escobar B, Palacios B, Gomez MJ, Izquierdo-Garcia JL, Flores L, Jimenez-Borreguero LJ, Aragones J, Ruiz-Cabello J, Torres M, Martin-Puig S, Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation. Dev Cell. 2016 Dec 19;39(6):724-739
5	J:122971 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE, A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29;129(7):1365-76
1*	J:293579 Moumne O, Chowdhurry R, Doll C, Pereira N, Hashimi M, Grindrod T, Dollar JJ, Riva A, Kasahara H, Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies. Front Cardiovasc Med. 2018;5:100
2	J:77375 Nguyen-Tran VT, Kubalak SW, Minamisawa S, Fiset C, Wollert KC, Brown AB, Ruiz-Lozano P, Barrere-Lemaire S, Kondo R, Norman LW, Gourdie RG, Rahme MM, Feld GK, Clark RB, Giles WR, Chien KR, A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages. Cell. 2000 Sep 1;102(5):671-82
3	J:108905 Nicolas M, Dememes D, Martin A, Kupershmidt S, Barhanin J, KCNQ1/KCNE1 potassium channels in mammalian vestibular dark cells. Hear Res. 2001 Mar;153(1-2):132-45
1*	J:167169 Park CY, Pierce SA, von Drehle M, Ivey KN, Morgan JA, Blau HM, Srivastava D, skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20750-5
6*	J:80502 Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A, Human chromosome 21 gene expression atlas in the mouse. Nature. 2002 Dec 5;420(6915):582-6
1	J:354224 Van Wauwe J, Mahy A, Craps S, Ekhteraei-Tousi S, Vrancaert P, Kemps H, Dheedene W, Donate Puertas R, Trenson S, Roderick HL, Beerens M, Luttun A, PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates. Life Sci Alliance. 2024 Dec;7(12)
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:354242 Wu Y, Chen S, Huang G, Zhang L, Zhong L, Feng Y, Wen P, Liu J, Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system. Theranostics. 2024;14(12):4894-4915
1	J:150452 Zhou B, Ma Q, Kong SW, Hu Y, Campbell PH, McGowan FX, Ackerman KG, Wu B, Zhou B, Tevosian SG, Pu WT, Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart. J Clin Invest. 2009 Jun;119(6):1462-76
1	J:336753 Zinina VV, Sauer M, Nigmatullina L, Kreim N, Soshnikova N, TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine. Cells. 2023 May 23;12(11)