Gene Expression Literature Summary

• Symbol: Lgals1
• Name: lectin, galactose binding, soluble 1
• ID: MGI:96777

30 matching records from 30 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E2.5	E3.5	E4.5	E5.5	E6.5	E7.5	E8.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E13	E13.5	E14	E14.5	E15.5	E16	E16.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)			1	5			1			1		3	2		1				3		2			1	1	6
In situ RNA (section)	1	1	1	1	1	1	1			1		3	2	3	1	1	1	7	3	1	1		1	1	1	5
In situ RNA (whole mount)									1	1	1	2			1	2									1
Northern blot										1		1	1	1		1		1				1				2
Western blot																										4
RT-PCR								1									1			1				1		2
cDNA clones							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lgals1  lectin, galactose binding, soluble 1   (Synonyms: Gal-1, Galbp, galectin-1, L14, Lect14)
Results	Reference
1*	J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
1	J:235148 Anderson DM, Cannavino J, Li H, Anderson KM, Nelson BR, McAnally J, Bezprozvannaya S, Liu Y, Lin W, Liu N, Bassel-Duby R, Olson EN, Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4494-503
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
2	J:130208 Blois SM, Ilarregui JM, Tometten M, Garcia M, Orsal AS, Cordo-Russo R, Toscano MA, Bianco GA, Kobelt P, Handjiski B, Tirado I, Markert UR, Klapp BF, Poirier F, Szekeres-Bartho J, Rabinovich GA, Arck PC, A pivotal role for galectin-1 in fetomaternal tolerance. Nat Med. 2007 Dec;13(12):1450-7
2	J:70006 Brennan J, Lu CC, Norris DP, Rodriguez TA, Beddington RS, Robertson EJ, Nodal signalling in the epiblast patterns the early mouse embryo. Nature. 2001 Jun 21;411(6840):965-9
1	J:353339 Butts JC, Wu SR, Durham MA, Dhindsa RS, Revelli JP, Ljungberg MC, Saulnier O, McLaren ME, Taylor MD, Zoghbi HY, A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain. Dev Cell. 2024 Aug 19;59(16):2171-2188.e7
3	J:332918 Cai S, Si N, Wang Y, Yin N, Transcriptomic analysis of the upper lip and primary palate development in mice. Front Genet. 2022;13:1039850
2	J:47227 Colnot C, Fowlis D, Ripoche MA, Bouchaert I, Poirier F, Embryonic implantation in galectin 1/galectin 3 double mutant mice. Dev Dyn. 1998 Apr;211(4):306-13
2	J:31899 Colnot C, Ripoche MA, Scaerou F, Foulis D, Poirier F, Galectins in mouse embryogenesis. Biochem Soc Trans. 1996 Feb;24(1):141-6
1*	J:148410 Combes AN, Lesieur E, Harley VR, Sinclair AH, Little MH, Wilhelm D, Koopman P, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn. 2009 May;238(5):1033-41
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:47784 Dragatsis I, Efstratiadis A, Zeitlin A, Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues. Development. 1998 Apr;125(8):1529-39
5*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:50869 Ko MSH, Threat TA, Wang X, Horton JH, Cui Y, Pryor E, Paris J , Wells-Smith J , Kitchen JR , Rowe LB , Eppig J , Satoh T , Brant L , Fujiwara H , Yotsumoto S , Nakashima H, Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
2	J:54886 Lasserre C, Colnot C, Brechot C, Poirier F, HIP/PAP gene, encoding a C-type lectin overexpressed in primary liver cancer, is expressed in nervous system as well as in intestine and pancreas of the postimplantation mouse embryo. Am J Pathol. 1999 May;154(5):1601-10
4	J:300509 Liu Y, Zhou X, Hu N, Wang C, Zhao L, P311 regulates distal lung development via its interaction with several binding proteins. Mech Dev. 2020 Sep;163:103633
1	J:40596 McClatchey AI, Saotome I, Ramesh V, Gusella JF, Jacks T, The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes Dev. 1997 May 15;11(10):1253-65
1*	J:241850 Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A, Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
2	J:251979 Pasquini JM, Barrantes FJ, Quinta HR, Normal development of spinal axons in early embryo stages and posterior locomotor function is independent of GAL-1. J Comp Neurol. 2017 Sep 1;525(13):2861-2875
6	J:35047 Phillips B, Knisley K, Weitlauf KD, Dorsett J, Lee V, Weitlauf H, Differential expression of two beta-galactoside-binding lectins in the reproductive tracts of pregnant mice. Biol Reprod. 1996 Sep;55(3):548-58
4	J:16245 Poirier F, Robertson EJ, Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin. Development. 1993 Dec;119(4):1229-36
21	J:1106 Poirier F, Timmons PM, Chan CT, Guenet JL, Rigby PW, Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre- and post-implantation development. Development. 1992 May;115(1):143-55
2	J:343286 Queen R, Crosier M, Eley L, Kerwin J, Turner JE, Yu J, Alqahtani A, Dhanaseelan T, Overman L, Soetjoadi H, Baldock R, Coxhead J, Boczonadi V, Laude A, Cockell SJ, Kane MA, Lisgo S, Henderson DJ, Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves. PLoS Genet. 2023 Nov;19(11):e1010777
8*	J:153078 Shoji H, Deltour L, Nakamura T, Tajbakhsh S, Poirier F, Expression pattern and role of Galectin1 during early mouse myogenesis. Dev Growth Differ. 2009 Sep;51(7):607-15
4*	J:105234 Tenne-Brown J, Puche AC, Key B, Expression of galectin-1 in the mouse olfactory system. Int J Dev Biol. 1998 Sep;42(6):791-9
1	J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
7	J:74242 Timmons PM, Rigby PW, Poirier F, The murine seminiferous epithelial cycle is pre-figured in the Sertoli cells of the embryonic testis. Development. 2002 Feb;129(3):635-47
2	J:194044 Walcher T, Xie Q, Sun J, Irmler M, Beckers J, Ozturk T, Niessing D, Stoykova A, Cvekl A, Ninkovic J, Gotz M, Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation. Development. 2013 Mar;140(5):1123-36