Gene Expression Literature Summary

• Symbol: Lmnb2
• Name: lamin B2
• ID: MGI:96796

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E2	E2.5	E3	E3.5	E6	E7.5	E8.5	E9.5	E10.5	E11.5	E12.5	E15.5	E16.5	E17.5	E18	E18.5	E19	E19.5	E	P
Immunohistochemistry (section)						1		1	1	1		1	1	1	2		4	1		1	5
Immunohistochemistry (whole mount)	1		1	1	1																1
In situ reporter (knock in)								1			1		1	1					1		2
Western blot			1		1							1			1	1	3	1		1	4
RT-PCR		1		1	1		1										2	1		1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lmnb2  lamin B2   (Synonyms: lamin B3)
Results	Reference
1*	J:307035 Chen NY, Kim PH, Tu Y, Yang Y, Heizer PJ, Young SG, Fong LG, Increased expression of LAP2beta eliminates nuclear membrane ruptures in nuclear lamin-deficient neurons and fibroblasts. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2107770118
1*	J:282806 Chen NY, Yang Y, Weston TA, Belling JN, Heizer P, Tu Y, Kim P, Edillo L, Jonas SJ, Weiss PS, Fong LG, Young SG, An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25870-25879
4	J:144707 Chiu SY, Asai N, Costantini F, Hsu W, SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages. PLoS Biol. 2008 Dec 16;6(12):e310
6	J:158610 Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG, Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81
7	J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93
3*	J:119954 Cui XS, Li XY, Shen XH, Bae YJ, Kang JJ, Kim NH, Transcription profile in mouse four-cell, morula, and blastocyst: Genes implicated in compaction and blastocoel formation. Mol Reprod Dev. 2007 Feb;74(2):133-43
1*	J:245014 Giacomini C, Mahajani S, Ruffilli R, Marotta R, Gasparini L, Lamin B1 protein is required for dendrite development in primary mouse cortical neurons. Mol Biol Cell. 2016 Jan 01;27(1):35-47
1	J:336184 Hayashi S, Oe S, Koike T, Seki-Omura R, Nakano Y, Hirahara Y, Tanaka S, Ito T, Yasukochi Y, Higasa K, Kitada M, OLIG2 is an in vivo bookmarking transcription factor in the developing neural tube in mouse. J Neurochem. 2023 May;165(3):303-317
2	J:16563 Hoger TH, Zatloukal K, Waizenegger I, Krohne G, Characterization of a second highly conserved B-type lamin present in cells previously thought to contain only a single B-type lamin [published erratum appears in Chromosoma 1990 Dec;100(1):67-9]. Chromosoma. 1990 Oct;99(6):379-90
1	J:117378 Hosoya-Ohmura S, Mochizuki N, Suzuki M, Ohneda O, Ohneda K, Yamamoto M, GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo. J Biol Chem. 2006 Oct 27;281(43):32820-30
7	J:289360 Houliston E, Guilly MN, Courvalin JC, Maro B, Expression of nuclear lamins during mouse preimplantation development. Development. 1988 Feb;102(2):271-8
9	J:197315 Jung HJ, Nobumori C, Goulbourne CN, Tu Y, Lee JM, Tatar A, Wu D, Yoshinaga Y, de Jong PJ, Coffinier C, Fong LG, Young SG, Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration. Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1923-32
1*	J:203004 Karunakaran DK, Congdon S, Guerrette T, Banday AR, Lemoine C, Chhaya N, Kanadia R, The expression analysis of Sfrs10 and Celf4 during mouse retinal development. Gene Expr Patterns. 2013 Dec;13(8):425-36
1	J:160544 Kim CE, Perez A, Perkins G, Ellisman MH, Dauer WT, A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9861-6
1	J:178993 Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y, Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science. 2011 Dec 23;334(6063):1706-10
1	J:309479 Lee JM, Jung HJ, Fong LG, Young SG, Do lamin B1 and lamin B2 have redundant functions?. Nucleus. 2014 Jul-Aug;5(4):287-92
4	J:220914 Lee JM, Tu Y, Tatar A, Wu D, Nobumori C, Jung HJ, Yoshinaga Y, Coffinier C, de Jong PJ, Fong LG, Young SG, Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2. Mol Biol Cell. 2014 May;25(10):1666-75
1	J:270627 Sakakibara I, Wurmser M, Dos Santos M, Santolini M, Ducommun S, Davaze R, Guernec A, Sakamoto K, Maire P, Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. Skelet Muscle. 2016;6(1):30
2	J:246890 Stroud MJ, Feng W, Zhang J, Veevers J, Fang X, Gerace L, Chen J, Nesprin 1alpha2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol. 2017 Jul 03;216(7):1915-1924
1	J:322322 Tanno N, Takemoto K, Takada-Horisawa Y, Shimada R, Fujimura S, Tani N, Takeda N, Araki K, Ishiguro KI, FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis. iScience. 2022 Apr 15;25(4):104008
1*	J:91473 Vergnes L, Peterfy M, Bergo MO, Young SG, Reue K, Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10428-33