Gene Expression Literature Summary

• Symbol: Mertk
• Name: MER proto-oncogene tyrosine kinase
• ID: MGI:96965

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3	E3.5	E8.5	E9.5	E11.5	E13.5	E15	E15.5	E17.5	E18.5	P
Immunohistochemistry (section)									1	1
In situ RNA (section)					2	1		3	1	1	5
Northern blot											1
Western blot							1				3
RT-PCR	1	1	1	1		2		1	1		5
cDNA clones											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mertk  MER proto-oncogene tyrosine kinase   (Synonyms: Eyk, Mer, nmf12, Nyk, Tyro 12)
Results	Reference
1	J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040
2	J:312416 Bhattacharjee O, Ayyangar U, Kurbet AS, Lakshmanan V, Palakodeti D, Ginhoux F, Raghavan S, Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin. Front Immunol. 2021;12:718005
1*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1	J:271760 Gobe C, Elzaiat M, Meunier N, Andre M, Sellem E, Congar P, Jouneau L, Allais-Bonnet A, Naciri I, Passet B, Pailhoux E, Pannetier M, Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis. PLoS Genet. 2019 Feb;15(2):e1007909
9*	J:26233 Graham DK, Bowman GW, Dawson TL, Stanford WL, Earp HS, Snodgrass HR, Cloning and developmental expression analysis of the murine c-mer tyrosine kinase. Oncogene. 1995 Jun 15;10(12):2349-59
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:205051 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Sestan N, Gage FH, Lein ES, Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
1	J:229930 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G, The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5:e09584
2	J:141251 Pierce A, Bliesner B, Xu M, Nielsen-Preiss S, Lemke G, Tobet S, Wierman ME, Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. Mol Endocrinol. 2008 Nov;22(11):2481-95
3	J:306249 Rosin JM, Marsters CM, Malik F, Far R, Adnani L, Schuurmans C, Pittman QJ, Kurrasch DM, Embryonic Microglia Interact with Hypothalamic Radial Glia during Development and Upregulate the TAM Receptors MERTK and AXL following an Insult. Cell Rep. 2021 Jan 5;34(1):108587
2	J:220148 Salian-Mehta S, Xu M, Pierce A, Bliesner B, Tobet S, Wierman ME, Loss of Growth arrest specific gene 6 (Gas6) results in altered GnRH neuron migration, delayed vaginal opening and sexual maturation in mice. Mol Cell Endocrinol. 2014 Aug 5;393(1-2):164-70
2	J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:326953 Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, Frankel WN, McKhann GM 2nd, Sulzer D, Goldman JE, Tang G, Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex. Cell Rep. 2022 Jul 19;40(3):111085