Symbol Name ID |
Kitl
kit ligand MGI:96974 |
Age | E0.5 | E1 | E2 | E2.5 | E3 | E3.5 | E4 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19.5 | E20 | E | P |
Immunohistochemistry (section) | 1 | 2 | 1 | 5 | 1 | 3 | 4 | 4 | 1 | 1 | 3 | 2 | 1 | 4 | ||||||||||||||||||||
In situ RNA (section) | 1 | 2 | 3 | 2 | 4 | 1 | 5 | 4 | 11 | 1 | 8 | 1 | 12 | 14 | 3 | 3 | 1 | 3 | 1 | 10 | 1 | 1 | 18 | |||||||||||
Immunohistochemistry (whole mount) | 1 | 1 | 1 | 1 | ||||||||||||||||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | 3 | 1 | 2 | 1 | 1 | 1 | 1 | |||||||||||||||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | 1 | 1 | ||||||||||||||||||||||||||||
Northern blot | 1 | |||||||||||||||||||||||||||||||||
Western blot | 2 | 1 | 3 | 1 | 2 | |||||||||||||||||||||||||||||
RT-PCR | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 3 | 2 | 4 | 9 | 1 | 15 | 1 | 8 | 1 | 8 | 1 | 10 | 1 | 6 | 2 | 6 | 1 | 2 | 4 | 2 | 1 | 2 | 25 | ||||
cDNA clones | 1 |
Kitl kit ligand (Synonyms: blz, Gb, grizzle-belly, Kitlg, Mgf, SCF, SF, Sl, SLF, Steel, Steel factor, stem cell factor) | |
Results | Reference |
1* | J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95 |
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1* | J:19895 Ang SL, Rossant J, HNF-3 beta is essential for node and notochord formation in mouse development. Cell. 1994 Aug 26;78(4):561-74 |
5 | J:757 Arceci RJ, Pampfer S, Pollard JW, Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development. Dev Biol. 1992 May;151(1):1-8 |
1 | J:166319 Arnould C, Lelievre-Pegorier M, Ronco P, Lelongt B, MMP9 limits apoptosis and stimulates branching morphogenesis during kidney development. J Am Soc Nephrol. 2009 Oct;20(10):2171-80 |
2* | J:184980 Assimacopoulos S, Kao T, Issa NP, Grove EA, Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography. J Neurosci. 2012 May 23;32(21):7191-201 |
1* | J:109310 Ballow D, Meistrich ML, Matzuk M, Rajkovic A, Sohlh1 is essential for spermatogonial differentiation. Dev Biol. 2006 Jun 1;294(1):161-7 |
3 | J:23593 Bedell MA, Brannan CI, Evans EP, Copeland NG, Jenkins NA, Donovan PJ, DNA rearrangements located over 100 kb 5' of the Steel (Sl)-coding region in Steel-panda and Steel-contrasted mice deregulate Sl expression and cause female sterility by disrupting ovarian follicle development. Genes Dev. 1995 Feb 15;9(4):455-70 |
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1* | J:142800 Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS, Atlas of gene expression in the developing kidney at microanatomic resolution. (Erratum: Dev Cell 2009; 16:482). Dev Cell. 2008 Nov;15(5):781-91 |
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2 | J:225062 Chen SR, Zheng QS, Zhang Y, Gao F, Liu YX, Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration. BMC Biol. 2013;11:22 |
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1 | J:141453 Cheng J, Kang X, Zhang S, Yeh ET, SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell. 2007 Nov 2;131(3):584-95 |
1 | J:121300 Cholfin JA, Rubenstein JL, Patterning of frontal cortex subdivisions by Fgf17. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7652-7 |
5* | J:159378 Chou S, Lodish HF, Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7799-804 |
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1 | J:162165 Dudley B, Palumbo C, Nalepka J, Molyneaux K, BMP signaling controls formation of a primordial germ cell niche within the early genital ridges. Dev Biol. 2010 Jul 1;343(1-2):84-93 |
1* | J:13166 Duttlinger R, Manova K, Chu TY, Gyssler C, Zelenetz AD, Bachvarova RF, Besmer P, W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis. Development. 1993 Jul;118(3):705-17 |
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3* | J:138839 Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, Golden JA, Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet. 2008;17(23):3740-60 |
1 | J:217593 Garcia TX, Farmaha JK, Kow S, Hofmann MC, RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Development. 2014 Dec;141(23):4468-78 |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
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1 | J:241013 Grassmeyer J, Mukherjee M, deRiso J, Hettinger C, Bailey M, Sinha S, Visvader JE, Zhao H, Fogarty E, Surendran K, Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression. Dev Biol. 2017 Apr 01;424(1):77-89 |
1 | J:253278 Greig LC, Woodworth MB, Greppi C, Macklis JD, Ctip1 Controls Acquisition of Sensory Area Identity and Establishment of Sensory Input Fields in the Developing Neocortex. Neuron. 2016 Apr 20;90(2):261-77 |
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8 | J:147283 Gu Y, Runyan C, Shoemaker A, Surani A, Wylie C, Steel factor controls primordial germ cell survival and motility from the time of their specification in the allantois, and provides a continuous niche throughout their migration. Development. 2009 Apr;136(8):1295-303 |
6* | J:179622 Gu Y, Runyan C, Shoemaker A, Surani MA, Wylie C, Membrane-bound steel factor maintains a high local concentration for mouse primordial germ cell motility, and defines the region of their migration. PLoS One. 2011;6(10):e25984 |
7* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
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1 | J:96967 Hahn KL, Johnson J, Beres BJ, Howard S, Wilson-Rawls J, Lunatic fringe null female mice are infertile due to defects in meiotic maturation. Development. 2005 Feb;132(4):817-28 |
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1 | J:186529 He X, Yang WC, Wen XY, Tang D, Xiao L, Han J, Yu B, Zhang W, Mei F, Late embryonic and postnatal development of interstitial cells of cajal in mouse esophagus: distribution, proliferation and kit dependence. Cells Tissues Organs. 2012;196(2):175-88 |
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1 | J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41 |
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4* | J:202252 Jones RL, Pepling ME, KIT signaling regulates primordial follicle formation in the neonatal mouse ovary. Dev Biol. 2013 Oct 1;382(1):186-97 |
1 | J:277950 Kang HM, Huang S, Reidy K, Han SH, Chinga F, Susztak K, Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice. Cell Rep. 2016 Feb 2;14(4):861-871 |
1 | J:139007 Kataoka A, Shimogori T, Fgf8 controls regional identity in the developing thalamus. Development. 2008 Sep;135(17):2873-81 |
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1* | J:180844 Strauss TJ, Castrillon DH, Hammes SR, GATA-like protein-1 (GLP-1) is required for normal germ cell development during embryonic oogenesis. Reproduction. 2011 Feb;141(2):173-81 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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