Gene Expression Literature Summary

• Symbol: Myl1
• Name: myosin, light polypeptide 1
• ID: MGI:97269

35 matching records from 35 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E19	P
Immunohistochemistry (section)															1							1
In situ RNA (section)			1		1	1	2	1	2	1	4	1	1	1	5		2	1	2	2	1	2	1	1
In situ RNA (whole mount)	2	1	3	1	4		3		1		1		1		2							1		1
Northern blot																								4
Western blot											1													1
RT-PCR	1		1		2	1		1	1		4		2	2	1					2		3		3
cDNA clones					1		1
RNase protection											1				1				1			1		2
Nuclease S1																1					1			1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Myl1  myosin, light polypeptide 1   (Synonyms: MLC1f, MLC3f, Mylf)
Results	Reference
4*	J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000
2*	J:216142 Amann R, Wyder S, Slavotinek AM, Trueb B, The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41
3*	J:70450 Barton PJ, Harris AJ, Buckingham ME, Myosin light chain gene expression in developing and denervated fetal muscle in the mouse. Development. 1989 Dec;107(4):819-24
1*	J:24360 Braun T, Arnold HH, Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development. EMBO J. 1995 Mar 15;14(6):1176-86
1	J:279139 Cibi DM, Mia MM, Guna Shekeran S, Yun LS, Sandireddy R, Gupta P, Hota M, Sun L, Ghosh S, Singh MK, Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate. Elife. 2019 Jun 26;8:e45418
1	J:181488 Delgado-Olguin P, Huang Y, Li X, Christodoulou D, Seidman CE, Seidman JG, Tarakhovsky A, Bruneau BG, Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. Nat Genet. 2012;44(3):343-7
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:74051 Franco D, Campione M, Kelly R, Zammit PS, Buckingham M, Lamers WH, Moorman AF, Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart. Circ Res. 2000 Nov 24;87(11):984-91
1	J:287413 Gerber SD, Beauchamp P, Zhuang L, Villiger PM, Trueb B, Functional domains of the FgfrL1 receptor. Dev Biol. 2020 May 1;461(1):43-54
3	J:93818 Golding JP, Partridge TA, Beauchamp JR, King T, Brown NA, Gassmann M, Zammit PS, Mouse myotomes pairs exhibit left-right asymmetric expression of MLC3F and alpha-skeletal actin. Dev Dyn. 2004 Dec;231(4):795-800
1	J:191565 Grote P, Wittler L, Hendrix D, Koch F, Wahrisch S, Beisaw A, Macura K, Blass G, Kellis M, Werber M, Herrmann BG, The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse. Dev Cell. 2013 Jan 28;24(2):206-14
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:204470 Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T, Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis. Mech Dev. 2013 Nov-Dec;130(11-12):519-31
1	J:108465 Issa LL, Palmer SJ, Guven KL, Santucci N, Hodgson VR, Popovic K, Joya JE, Hardeman EC, MusTRD can regulate postnatal fiber-specific expression. Dev Biol. 2006 May 1;293(1):104-15
3	J:245044 Janssen L, Dupont L, Bekhouche M, Noel A, Leduc C, Voz M, Peers B, Cataldo D, Apte SS, Dubail J, Colige A, ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis. Angiogenesis. 2016 Jan;19(1):53-65
7*	J:77516 Jiang P, Song J, Gu G, Slonimsky E, Li E, Rosenthal N, Targeted deletion of the MLC1f/3f downstream enhancer results in precocious MLC expression and mesoderm ablation. Dev Biol. 2002 Mar 15;243(2):281-93
4*	J:24348 Kelly R, Alonso S, Tajbakhsh S, Cossu G, Buckingham M, Myosin light chain 3F regulatory sequences confer regionalized cardiac and skeletal muscle expression in transgenic mice. J Cell Biol. 1995 Apr;129(2):383-96
13*	J:49387 Kelly RG, Zammit PS, Mouly V, Butler-Browne G, Buckingham ME, Dynamic left/right regionalisation of endogenous myosin light chain 3F transcripts in the developing mouse heart. J Mol Cell Cardiol. 1998 Jun;30(6):1067-81
1	J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722
1	J:32267 Lyons GE, Buckingham ME, Tweedie S, Edwards YH, Carbonic anhydrase III, an early mesodermal marker, is expressed in embryonic mouse skeletal muscle and notochord. Development. 1991 Jan;111(1):233-44
7*	J:31856 Lyons GE, Ontell M, Cox R, Sassoon D, Buckingham M, The expression of myosin genes in developing skeletal muscle in the mouse embryo. J Cell Biol. 1990 Oct;111(4):1465-76
6*	J:34383 McGrew MJ, Bogdanova N, Hasegawa K, Hughes SH, Kitsis RN, Rosenthal N, Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus. Mol Cell Biol. 1996 Aug;16(8):4524-34
2	J:65651 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev. 2000 Nov;98(1-2):77-94
2	J:156719 Niro C, Demignon J, Vincent S, Liu Y, Giordani J, Sgarioto N, Favier M, Guillet-Deniau I, Blais A, Maire P, Six1 and Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotome. Dev Biol. 2010 Feb 15;338(2):168-82
7*	J:11854 Ontell M, Ontell MP, Sopper MM, Mallonga R, Lyons G, Buckingham M, Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles. Development. 1993 Apr;117(4):1435-44
4*	J:16215 Ontell MP, Sopper MM, Lyons G, Buckingham M, Ontell M, Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity. Dev Dyn. 1993 Nov;198(3):203-13
4*	J:29279 Patapoutian A, Yoon JK, Miner JH, Wang S, Stark K, Wold B, Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome. Development. 1995 Oct;121(10):3347-58
2	J:212185 Petchey LK, Risebro CA, Vieira JM, Roberts T, Bryson JB, Greensmith L, Lythgoe MF, Riley PR, Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9515-20
1*	J:317550 Sakamoto T, Matsuura TR, Wan S, Ryba DM, Kim JU, Won KJ, Lai L, Petucci C, Petrenko N, Musunuru K, Vega RB, Kelly DP, A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation. Circ Res. 2020 Jun 5;126(12):1685-1702
2	J:205050 Swinehart IT, Schlientz AJ, Quintanilla CA, Mortlock DP, Wellik DM, Hox11 genes are required for regional patterning and integration of muscle, tendon and bone. Development. 2013 Nov;140(22):4574-82
2*	J:141291 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H, Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511
1	J:186268 Vincent SD, Mayeuf A, Niro C, Saitou M, Buckingham M, Non conservation of function for the evolutionarily conserved prdm1 protein in the control of the slow twitch myogenic program in the mouse embryo. Mol Biol Evol. 2012 Oct;29(10):3181-91
1*	J:31611 Wang Y, Schnegelsberg PN, Dausman J, Jaenisch R, Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin. Nature. 1996 Feb 29;379(6568):823-5
2	J:206319 Welcker JE, Hernandez-Miranda LR, Paul FE, Jia S, Ivanov A, Selbach M, Birchmeier C, Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors. Development. 2013 Dec;140(24):4947-58
3	J:130500 Zammit PS, Cohen A, Buckingham ME, Kelly RG, Integration of embryonic and fetal skeletal myogenic programs at the myosin light chain 1f/3f locus. Dev Biol. 2008 Jan 1;313(1):420-33