Gene Expression Literature Summary

• Symbol: Ntf5
• Name: neurotrophin 5
• ID: MGI:97381

22 matching records from 22 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E10.5	E11.5	E12	E12.5	E13.5	E14	E14.5	E15.5	E16.5	E17	E17.5	E18.5	E19.5	P
Immunohistochemistry (section)					2	1		1				2	1		1
In situ RNA (section)		1	1			1		1	1				1		3
In situ RNA (whole mount)									1
In situ reporter (knock in)						1	1
Western blot				1	1										1
RT-PCR	1				1			2	1	4	1	1	2	1	7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ntf5  neurotrophin 5   (Synonyms: 2900040K06Rik, neurotrophin-4, NT-4, NT4, NT4/5, Ntf4, Ntf-5)
Results	Reference
3	J:160730 Alavian KN, Sgado P, Alberi L, Subramaniam S, Simon HH, Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression. Neural Dev. 2009;4:11
4*	J:157986 Childs AJ, Bayne RA, Murray AA, Martins Da Silva SJ, Collins CS, Spears N, Anderson RA, Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development. Dev Dyn. 2010 Feb 19;239(4):1211-1219
1	J:133953 Deppmann CD, Mihalas S, Sharma N, Lonze BE, Niebur E, Ginty DD, A model for neuronal competition during development. Science. 2008 Apr 18;320(5874):369-73
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
4	J:165547 Huang T, Krimm RF, Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system. Dev Dyn. 2010 Oct;239(10):2637-46
1	J:102289 Kablar B, Belliveau AC, Presence of neurotrophic factors in skeletal muscle correlates with survival of spinal cord motor neurons. Dev Dyn. 2005 Nov;234(3):659-69
1	J:126357 Kawamura K, Kawamura N, Fukuda J, Kumagai J, Hsueh AJ, Tanaka T, Regulation of preimplantation embryo development by brain-derived neurotrophic factor. Dev Biol. 2007 Nov 1;311(1):147-58
3	J:115894 Kim EY, Hong YB, Go SH, Lee B, Jung SC, Downregulation of neurotrophic factors in the brain of a mouse model of Gaucher disease; implications for neuronal loss in Gaucher disease. Exp Mol Med. 2006 Aug 31;38(4):348-56
1	J:192549 Liu Y, Rutlin M, Huang S, Barrick CA, Wang F, Jones KR, Tessarollo L, Ginty DD, Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland. Science. 2012 Dec 7;338(6112):1357-60
1*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1	J:57885 O'Connor R, Tessier-Lavigne M, Identification of maxillary factor, a maxillary process-derived chemoattractant for developing trigeminal sensory axons. Neuron. 1999 Sep;24(1):165-78
2	J:353621 Patel VN, Aure MH, Choi SH, Ball JR, Lane ED, Wang Z, Xu Y, Zheng C, Liu X, Martin D, Pailin JY, Prochazkova M, Kulkarni AB, van Kuppevelt TH, Ambudkar IS, Liu J, Hoffman MP, Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584
1	J:177268 Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X, A Shh/miR-206/BDNF Cascade Coordinates Innervation and Formation of Airway Smooth Muscle. J Neurosci. 2011 Oct 26;31(43):15407-15
2	J:93814 Reddy T, Kablar B, Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5(-/-):MyoD(-/-) and NT-3(-/-) embryos. Dev Dyn. 2004 Dec;231(4):683-92
1*	J:58028 Russo MA, Giustizieri ML, Favale A, Fantini MC, Campagnolo L, Konda D, Germano F, Farini D, Manna C, Siracusa G, Spatiotemporal patterns of expression of neurotrophins and neurotrophin receptors in mice suggest functional roles in testicular and epididymal morphogenesis. Biol Reprod. 1999 Oct;61(4):1123-32
1*	J:218012 Rutlin M, Ho CY, Abraira VE, Cassidy C, Woodbury CJ, Ginty DD, The cellular and molecular basis of direction selectivity of Adelta-LTMRs. Cell. 2014 Dec 18;159(7):1640-51
2*	J:85731 Spears N, Molinek MD, Robinson LL, Fulton N, Cameron H, Shimoda K, Telfer EE, Anderson RA, Price DJ, The role of neurotrophin receptors in female germ-cell survival in mouse and human. Development. 2003 Nov;130(22):5481-91
3	J:106341 Stephens HE, Belliveau AC, Gupta JS, Mirkovic S, Kablar B, The role of neurotrophins in the maintenance of the spinal cord motor neurons and the dorsal root ganglia proprioceptive sensory neurons. Int J Dev Neurosci. 2005 Nov;23(7):613-20
2	J:264123 Tanimizu N, Ichinohe N, Mitaka T, Intrahepatic bile ducts guide establishment of the intrahepatic nerve network in developing and regenerating mouse liver. Development. 2018 Apr 25;145(9):dev159095
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:197621 Ueno M, Fujita Y, Tanaka T, Nakamura Y, Kikuta J, Ishii M, Yamashita T, Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci. 2013 May;16(5):543-51