Symbol Name ID |
Plcg2
phospholipase C, gamma 2 MGI:97616 |
Age | E1 | E8.5 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14.5 | E15.5 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | ||||||||
In situ RNA (section) | 2 | |||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | ||||||||
Western blot | 1 | 1 | 2 | |||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 |
Plcg2 phospholipase C, gamma 2 (Synonyms: MGC:38590, Plcg-2, PLCgamma2) | |
Results | Reference |
3 | J:242531 Bedogni F, Cobolli Gigli C, Pozzi D, Rossi RL, Scaramuzza L, Rossetti G, Pagani M, Kilstrup-Nielsen C, Matteoli M, Landsberger N, Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms. Cereb Cortex. 2016 Jun;26(6):2517-2529 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:171969 He Y, Zhang H, Yu L, Gunel M, Boggon TJ, Chen H, Min W, Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal. 2010;3(116):ra26 |
1 | J:307823 Hoover C, Kondo Y, Shao B, McDaniel MJ, Lee R, McGee S, Whiteheart S, Bergmeier W, McEver RP, Xia L, Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin. Blood. 2021 May 20;137(20):2756-2769 |
6* | J:143529 Ichise H, Ichise T, Ohtani O, Yoshida N, Phospholipase C{gamma}2 is necessary for separation of blood and lymphatic vasculature in mice. Development. 2009 Jan;136(2):191-5 |
1 | J:348282 Ju H, Yu M, Du X, Xue S, Ye N, Sun L, Wu X, Xu H, Shen Q, Gestational diabetes mellitus induces congenital anomalies of the kidney and urinary tract in mice by altering RET/MAPK/ERK pathway. Biochem Biophys Res Commun. 2024 Jun 25;714:149959 |
1* | J:128289 Li Y, Chandrakanthan V, Day ML, O'Neill C, Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. Biol Reprod. 2007 Nov;77(5):813-21 |
2* | J:75316 Liao HJ, Kume T, McKay C, Xu MJ, Ihle JN, Carpenter G, Absence of Erythrogenesis and Vasculogenesis in Plcg1-deficient Mice. J Biol Chem. 2002 Mar 15;277(11):9335-41 |
1 | J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722 |
1 | J:154601 Seuntjens E, Nityanandam A, Miquelajauregui A, Debruyn J, Stryjewska A, Goebbels S, Nave KA, Huylebroeck D, Tarabykin V, Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci. 2009 Nov;12(11):1373-80 |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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