Gene Expression Literature Summary

• Symbol: Polb
• Name: polymerase (DNA directed), beta
• ID: MGI:97740

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E13.5	E14.5	E18.5	P
Immunohistochemistry (section)									1
In situ RNA (section)							2
Western blot						1			2
RT-PCR	1	1	1	1	2	1		1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Polb  polymerase (DNA directed), beta   (Synonyms: A430088C08Rik, Pol beta)
Results	Reference
1	J:228779 Alpern D, Langer D, Ballester B, Le Gras S, Romier C, Mengus G, Davidson I, TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation. Elife. 2014;3:e03613
2*	J:279805 Baleriola J, Alvarez-Lindo N, de la Villa P, Bernad A, Blanco L, Suarez T, de la Rosa EJ, Increased neuronal death and disturbed axonal growth in the Polmu-deficient mouse embryonic retina. Sci Rep. 2016 May 13;6:25928
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:70848 Gonda H, Sugai M, Katakai T, Sugo N, Aratani Y, Koyama H, Mori KJ, Shimizu A, DNA polymerase beta is not essential for the formation of palindromic (P) region of T cell receptor gene. Immunol Lett. 2001 Aug 1;78(1):45-9
2	J:286844 Kim J, Kim K, Mo JS, Lee Y, Atm deficiency in the DNA polymerase beta null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation. Nucleic Acids Res. 2020 Apr 17;48(7):3678-3691
1	J:195178 Linke M, May A, Reifenberg K, Haaf T, Zechner U, The impact of ovarian stimulation on the expression of candidate reprogramming genes in mouse preimplantation embryos. Cytogenet Genome Res. 2013;139(2):71-9
1	J:161421 Mann W, Haaf T, Single cell RT-PCR on mouse embryos: a general approach for developmental biology. Methods Mol Biol. 2010;630:3-12
4*	J:145796 May A, Kirchner R, Muller H, Hartmann P, El Hajj N, Tresch A, Zechner U, Mann W, Haaf T, Multiplex rt-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres. Biol Reprod. 2009 Jan;80(1):194-202
1	J:118190 Sugo N, Niimi N, Aratani Y, Masutani M, Suzuki H, Koyama H, Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase beta-deficient mice. Biochem Biophys Res Commun. 2007 Mar 16;354(3):656-61
1	J:299668 Uyeda A, Onishi K, Hirayama T, Hattori S, Miyakawa T, Yagi T, Yamamoto N, Sugo N, Suppression of DNA Double-Strand Break Formation by DNA Polymerase beta in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons. J Neurosci. 2020 Nov 18;40(47):9012-9027