Gene Expression Literature Summary

• Symbol: Prnp
• Name: prion protein
• ID: MGI:97769

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8	E8.5	E9.5	E10	E10.5	E11.5	E12	E12.5	E13.5	E14	E14.5	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)			1	2		2	2			1	1		1	1		1		1		2	2	1
In situ RNA (section)	1				1	1			2			2		5	4		3				1	4
Immunohistochemistry (whole mount)			1		1	1		1
In situ RNA (whole mount)		1	2	2	1
Western blot												1			1		1		1		1	2
RT-PCR									1		1	1		1	1		3		1		3	5
cDNA clones																	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Prnp  prion protein   (Synonyms: CD230, Prn-i, Prn-p, PrP, PrPC, PrPSc, Sinc)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
6*	J:174473 Benvegnu S, Poggiolini I, Legname G, Neurodevelopmental expression and localization of the cellular prion protein in the central nervous system of the mouse. J Comp Neurol. 2010 Jun 1;518(11):1879-91
2	J:187211 Bribian A, Fontana X, Llorens F, Gavin R, Reina M, Garcia-Verdugo JM, Torres JM, de Castro F, del Rio JA, Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS. PLoS One. 2012;7(4):e33872
1*	J:142800 Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS, Atlas of gene expression in the developing kidney at microanatomic resolution. (Erratum: Dev Cell 2009; 16:482). Dev Cell. 2008 Nov;15(5):781-91
1*	J:297073 Chen Z, Morales JE, Avci N, Guerrero PA, Rao G, Seo JH, McCarty JH, The vascular endothelial cell-expressed prion protein doppel promotes angiogenesis and blood-brain barrier development. Development. 2020 Sep 23;147(18):dev193094
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:124048 Hajj GN, Lopes MH, Mercadante AF, Veiga SS, da Silveira RB, Santos TG, Ribeiro KC, Juliano MA, Jacchieri SG, Zanata SM, Martins VR, Cellular prion protein interaction with vitronectin supports axonal growth and is compensated by integrins. J Cell Sci. 2007 Jun 1;120(Pt 11):1915-26
6*	J:159669 Hajj GN, Santos TG, Cook ZS, Martins VR, Developmental expression of prion protein and its ligands stress-inducible protein 1 and vitronectin. J Comp Neurol. 2009 Nov 20;517(3):371-84
10	J:170068 Hidaka K, Shirai M, Lee JK, Wakayama T, Kodama I, Schneider MD, Morisaki T, The cellular prion protein identifies bipotential cardiomyogenic progenitors. Circ Res. 2010 Jan 8;106(1):111-9
3*	J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27
1*	J:176496 Khalife M, Young R, Passet B, Halliez S, Vilotte M, Jaffrezic F, Marthey S, Beringue V, Vaiman D, Le Provost F, Laude H, Vilotte JL, Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis. PLoS One. 2011;6(8):e23253
8*	J:167050 Khan QE, Press CM, Sehic A, Landin MA, Risnes S, Osmundsen H, Expression of prion gene and presence of prion protein during development of mouse molar tooth germ. Eur J Oral Sci. 2010 Dec;118(6):559-65
9	J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139
2*	J:297547 Leca I, Phillips AW, Hofer I, Landler L, Ushakova L, Cushion TD, Durnberger G, Stejskal K, Mechtler K, Keays DA, A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse. PLoS Genet. 2020 Nov;16(11):e1009104
1	J:123441 Lopes MH, Hajj GN, Muras AG, Mancini GL, Castro RM, Ribeiro KC, Brentani RR, Linden R, Martins VR, Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways. J Neurosci. 2005 Dec 7;25(49):11330-9
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
5*	J:1109 Manson J, West JD, Thomson V, McBride P, Kaufman MH, Hope J, The prion protein gene: a role in mouse embryogenesis?. Development. 1992 May;115(1):117-22
2*	J:172286 Miranda A, Pericuesta E, Ramirez MA, Gutierrez-Adan A, Prion protein expression regulates embryonic stem cell pluripotency and differentiation. PLoS One. 2011;6(4):e18422
3*	J:141291 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H, Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:284147 Velecela V, Torres-Cano A, Garcia-Melero A, Ramiro-Pareta M, Muller-Sanchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martinez FO, Martinez-Estrada OM, Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4. Development. 2019 Oct 17;146(20):dev178723
1	J:235644 Wu Y, Wei FY, Kawarada L, Suzuki T, Araki K, Komohara Y, Fujimura A, Kaitsuka T, Takeya M, Oike Y, Suzuki T, Tomizawa K, Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. PLoS Genet. 2016 Sep;12(9):e1006355